Publications by authors named "Steven Angus"

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The impact and ethical consequences of tuition-free medical schools on improving diversity in health care.
Albert E Zhou, Trevor Sutton, Jeffrey Hines, Steven Angus, Hao Feng

Clin Dermatol· December 2025

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Intra-tumoral hypoxia promotes CD8 T cell dysfunction via chronic activation of integrated stress response transcription factor ATF4.
Coral Del Mar Alicea Pauneto, Brian P Riesenberg, Evelyn J Gandy, Andrew S Kennedy, Genevieve T Clutton, Steven P Angus

Immunity· October 2025

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A haploinsufficiency restoration strategy corrects neurobehavioral deficits in Nf1+/- mice.
Su Jung Park, Jodi L Lukkes, Ka-Kui Chan, Hayley P Drozd, Callie B Burgin, Steven P Angus

J Clin Invest· July 2025

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TGFβ-dependent signaling drives tumor growth and aberrant extracellular matrix dynamics in NF1-associated plexiform neurofibroma.
Mohannad Abu-Sultanah, Zhuan Zhou, Chunhui Jiang, Dana K Mitchell, Waylan K Bessler, Steven P Angus

Sci Adv· June 2025

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Identifying and exploiting combinatorial synthetic lethality by characterizing adaptive kinome rewiring of EGFRvIII-driven glioblastoma.
Benjamin Lin, Abigail K Shelton, Erin Smithberger, Julia Ziebro, Kasey R Skinner, Steven P Angus

Acta Neuropathol Commun· June 2025

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An induced pluripotent stem cell model of Schwann cell differentiation reveals NF2- related gene regulatory networks.
Olivia Lazaro, Sihong Li, William Carter, Jake Smiley, Oluwamayowa Awosika, Steven P Angus

Res Sq· June 2025

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DLK1 Distinguishes Subsets of NF1-Associated Malignant Peripheral Nerve Sheath Tumors with Divergent Molecular Signatures.
Dana K Mitchell, Kylee Brewster, Stavriani C Makri, Jaffar Khan, Eric A Albright, Steven P Angus

Clin Cancer Res· May 2025

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Diversity Recruitment in Cardiovascular Specialties: Barriers and Opportunities in Postgraduate Training Programs.
Maria Guerrero, Edmund T Takata, Ervin Ham, Laura Hohenstein, Taylor Amore, Steven Angus

JACC Adv· February 2025

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Selumetinib in adults with NF1 and inoperable plexiform neurofibroma: a phase 2 trial.
Andrea M Gross, Geraldine O'Sullivan Coyne, Eva Dombi, Cecilia Tibery, William G Herrick, Steven P Angus

Nat Med· January 2025

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Hydroxychloroquine prevents resistance and potentiates the antitumor effect of SHP2 inhibition in NF1-associated malignant peripheral nerve sheath tumors.
Sameer Farouk Sait, Kwan Ho Tang, Steven P Angus, Rebecca Brown, Daochun Sun

Proc Natl Acad Sci U S A· January 2025

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Ethics of residency programs and fellowships that electively withdraw from the National Resident Matching Program.
Albert E Zhou, Bryan Carmody, Christian Gronbeck, Steven Angus, Brett Sloan

Clin Dermatol· December 2024

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Efficacy of the Allosteric MEK Inhibitor Trametinib in Relapsed and Refractory Juvenile Myelomonocytic Leukemia: a Report from the Children's Oncology Group.
Elliot Stieglitz, Alex G Lee, Steven P Angus, Christopher Davis, Donald A Barkauskas

Cancer Discov· September 2024

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Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK.
Long-Sheng Chang, Janet L Oblinger, Abbi E Smith, Marc Ferrer, Steven P Angus

PLoS One· July 2024

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A novel induced pluripotent stem cell model of Schwann cell differentiation reveals - related gene regulatory networks of the extracellular matrix.
Olivia Lazaro, Sihong Li, William Carter, Oluwamayowa Awosika, Sylvia Robertson, Steven P Angus

bioRxiv· July 2024

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Oxygen tension-dependent variability in the cancer cell kinome impacts signaling pathways and response to targeted therapies.
Adedeji K Adebayo, Poornima Bhat-Nakshatri, Christopher Davis, Steven P Angus, Cihat Erdogan

iScience· June 2024

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Correction: Combined CDK4/6 and ERK1/2 Inhibition Enhances Antitumor Activity in NF1-Associated Plexiform Neurofibroma.
Alyssa C Flint, Dana K Mitchell, Steven P Angus, Abbi E Smith, Waylan Bessler

Clin Cancer Res· May 2024

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Neratinib, a pan ERBB/HER inhibitor, restores sensitivity of -null, melanoma to BRAF/MEK inhibition.
Evan DuBose, Samantha M Bevill, Dana K Mitchell, Noah Sciaky, Brian T Golitz, Steven P Angus

Front Oncol· May 2024

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Spatial Gene-Expression Profiling Unveils Immuno-oncogenic Programs of NF1-Associated Peripheral Nerve Sheath Tumor Progression.
Dana K Mitchell, Breanne Burgess, Emily E White, Abbi E Smith, Elizabeth A Sierra Potchanant, Steven P Angus

Clin Cancer Res· March 2024

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Combined CDK4/6 and ERK1/2 Inhibition Enhances Antitumor Activity in NF1-Associated Plexiform Neurofibroma.
Alyssa C Flint, Dana K Mitchell, Steven P Angus, Abbi E Smith, Waylan Bessler

Clin Cancer Res· September 2023

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Ravidomycin Analogs from sp. Exhibit Altered Antimicrobial and Cytotoxic Selectivity.
Kyoung Jin Park, Sarah Maier, Chengqian Zhang, Shelley A H Dixon, Douglas B Rusch, Steven P Angus

J Nat Prod· August 2023

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The Undergraduate to Graduate Medical Education Transition as a Systems Problem: A Root Cause Analysis.
Jennifer L Swails, Steven Angus, Michael A Barone, Jessica Bienstock, Jesse Burk-Rafel

Acad Med· February 2023

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Rates of Adverse Events in Hospitalized Patients After Summer-Time Resident Changeover in the United States: Is There a July Effect?
Mark L Metersky, Noel Eldridge, Yun Wang, Sheila Eckenrode, Deron Galusha, Steven Angus

J Patient Saf· April 2022

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High-content image-based analysis and proteomic profiling identifies Tau phosphorylation inhibitors in a human iPSC-derived glutamatergic neuronal model of tauopathy.
Chialin Cheng, Surya A Reis, Emily T Adams, Daniel M Fass, Steven P Angus

Sci Rep· August 2021

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FOXA1 and adaptive response determinants to HER2 targeted therapy in TBCRC 036.
Steven P Angus, Timothy J Stuhlmiller, Gaurav Mehta, Samantha M Bevill, Daniel R Goulet

NPJ Breast Cancer· May 2021

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SOX4 and SMARCA4 cooperatively regulate PI3k signaling through transcriptional activation of TGFBR2.
Gaurav A Mehta, Steven P Angus, Christen A Khella, Kevin Tong, Pooja Khanna

NPJ Breast Cancer· April 2021

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