Publications by authors named "Steven Ansell"

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The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs.
Akin Akinc, Martin A Maier, Muthiah Manoharan, Kevin Fitzgerald, Muthusamy Jayaraman, Steven Ansell

Nat Nanotechnol· December 2019

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Influence of Polyethylene Glycol Lipid Desorption Rates on Pharmacokinetics and Pharmacodynamics of siRNA Lipid Nanoparticles.
Barbara L Mui, Ying K Tam, Muthusamy Jayaraman, Steven M Ansell, Xinyao Du

Mol Ther Nucleic Acids· December 2013

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Biodegradable lipids enabling rapidly eliminated lipid nanoparticles for systemic delivery of RNAi therapeutics.
Martin A Maier, Muthusamy Jayaraman, Shigeo Matsuda, Ju Liu, Scott Barros, Steven M Ansell

Mol Ther· August 2013

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Small molecule ligands for enhanced intracellular delivery of lipid nanoparticle formulations of siRNA.
Yuen Yi C Tam, Sam Chen, Josh Zaifman, Ying K Tam, Paulo J C Lin, Steven Ansell

Nanomedicine· July 2013

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Effects of block copolymer properties on nanocarrier protection from in vivo clearance.
Suzanne M D'Addio, Walid Saad, Steven M Ansell, John J Squiers, Douglas H Adamson

J Control Release· August 2012

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Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo.
Muthusamy Jayaraman, Steven M Ansell, Barbara L Mui, Ying K Tam, Jianxin Chen

Angew Chem Int Ed Engl· August 2012

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The use of radioactive marker as a tool to evaluate the drug release in plasma and particle biodistribution of block copolymer nanoparticles.
Sharon Johnstone, Steven Ansell, Sherwin Xie, Lawrence Mayer, Paul Tardi

J Drug Deliv· November 2011

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Modulating the therapeutic activity of nanoparticle delivered paclitaxel by manipulating the hydrophobicity of prodrug conjugates.
Steven M Ansell, Sharon A Johnstone, Paul G Tardi, Lily Lo, Sherwin Xie

J Med Chem· June 2008

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Micelles as intermediates in the preparation of protein-liposome conjugates.
Jennifer Takasaki, Steven M Ansell

Bioconjug Chem· July 2006

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Methods for the preparation of protein-oligonucleotide-lipid constructs.
Jennifer Takasaki, Sameersingh G Raney, Ghania Chikh, Laura Sekirov, Irina Brodsky, Steven M Ansell

Bioconjug Chem· July 2006

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Immunogenicity and rapid blood clearance of liposomes containing polyethylene glycol-lipid conjugates and nucleic Acid.
Sean C Semple, Troy O Harasym, Kathy A Clow, Steven M Ansell, Sandra K Klimuk

J Pharmacol Exp Ther· March 2005

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Hormone replacement therapy and risk of non-hodgkin lymphoma and chronic lymphocytic leukemia.
James R Cerhan, Celine M Vachon, Thomas M Habermann, Steven M Ansell, Thomas E Witzig

Cancer Epidemiol Biomarkers Prev· November 2002

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