Publications by authors named "Steven Bryce"

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Application of Biological Modifiers to a Multiplexed, Human Cell-Based DNA Damage Assay Provides Mechanistic Information on Genotoxicity and Molecular Targets.
Steven M Bryce, Svetlana L Avlasevich, Adam Conrad, Nikki E Hall, Kyle Tichenor

Environ Mol Mutagen· June 2025

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Mitigation of Volatile Chemicals' Effect on Adjacent Microtiter Plate Wells.
Svetlana L Avlasevich, Erica Briggs, Kyle Tichenor, Adam Conrad, Nikki Hall, Steven M Bryce

Environ Mol Mutagen· March 2025

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Visualization strategies to aid interpretation of high-dimensional genotoxicity data.
Stephen D Dertinger, Erica Briggs, Yusuf Hussien, Steven M Bryce, Svetlana L Avlasevich

Environ Mol Mutagen· June 2024

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In vitro human cell-based aneugen molecular mechanism assay.
Nikki E Hall, Kyle Tichenor, Steven M Bryce, Jeffrey C Bemis, Stephen D Dertinger

Environ Mol Mutagen· March 2022

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Biomarkers of DNA damage response improve in vitro micronucleus assays by revealing genotoxic mode of action and reducing the occurrence of irrelevant positive results.
Svetlana Avlasevich, Tina Pellegrin, Manali Godse, Steven Bryce, Jeffrey Bemis

Mutagenesis· November 2021

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Kinetics of γH2AX and phospho-histone H3 following pulse treatment of TK6 cells provides insights into clastogenic activity.
Steven M Bryce, Stephen D Dertinger, Jeffrey C Bemis

Mutagenesis· July 2021

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The use of benchmark dose uncertainty measurements for robust comparative potency analyses.
Ryan P Wheeldon, Stephen D Dertinger, Steven M Bryce, Jeffrey C Bemis, George E Johnson

Environ Mol Mutagen· March 2021

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Benchmark Dose Analysis of DNA Damage Biomarker Responses Provides Compound Potency and Adverse Outcome Pathway Information for the Topoisomerase II Inhibitor Class of Compounds.
Ryan P Wheeldon, Derek T Bernacki, Stephen D Dertinger, Steven M Bryce, Jeffrey C Bemis

Environ Mol Mutagen· April 2020

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3Rs-friendly approach to exogenous metabolic activation that supports high-throughput genetic toxicology testing.
Shuchang Tian, Aiyana Cyr, Karen Zeise, Steven M Bryce, Nikki Hall

Environ Mol Mutagen· April 2020

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Application of the adverse outcome pathway framework to genotoxic modes of action.
Jennifer C Sasaki, Ashley Allemang, Steven M Bryce, Laura Custer, Kerry L Dearfield

Environ Mol Mutagen· January 2020

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Evidence for an Aneugenic Mechanism of Action for Micronucleus Induction by Black Cohosh Extract.
Derek T Bernacki, Steven M Bryce, Jeffrey C Bemis, Stephen D Dertinger, Kristine L Witt

Environ Mol Mutagen· December 2019

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Aneugen Molecular Mechanism Assay: Proof-of-Concept With 27 Reference Chemicals.
Derek T Bernacki, Steven M Bryce, Jeffrey C Bemis, Stephen D Dertinger

Toxicol Sci· August 2019

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Predictions of genotoxic potential, mode of action, molecular targets, and potency via a tiered multiflow® assay data analysis strategy.
Stephen D Dertinger, Andrew R Kraynak, Ryan P Wheeldon, Derek T Bernacki, Steven M Bryce

Environ Mol Mutagen· July 2019

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TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence.
Thomas G Bird, Miryam Müller, Luke Boulter, David F Vincent, Rachel A Ridgway, Steven Bryce

Sci Transl Med· August 2018

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Black cohosh extracts and powders induce micronuclei, a biomarker of genetic damage, in human cells.
Stephanie L Smith-Roe, Carol D Swartz, Kim G Shepard, Steven M Bryce, Stephen D Dertinger

Environ Mol Mutagen· June 2018

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Comparative Genotoxicity of TEMPO and 3 of Its Derivatives in Mouse Lymphoma Cells.
Xiaoqing Guo, Ji-Eun Seo, Steven M Bryce, Jenna A Tan, Qiangen Wu

Toxicol Sci· May 2018

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Investigating the Generalizability of the MultiFlow ® DNA Damage Assay and Several Companion Machine Learning Models With a Set of 103 Diverse Test Chemicals.
Steven M Bryce, Derek T Bernacki, Stephanie L Smith-Roe, Kristine L Witt, Jeffrey C Bemis

Toxicol Sci· March 2018

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Interlaboratory evaluation of a multiplexed high information content in vitro genotoxicity assay.
Steven M Bryce, Derek T Bernacki, Jeffrey C Bemis, Richard A Spellman, Maria E Engel

Environ Mol Mutagen· April 2017

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γH2AX and p53 responses in TK6 cells discriminate promutagens and nongenotoxicants in the presence of rat liver S9.
Derek T Bernacki, Steven M Bryce, Jeffrey C Bemis, David Kirkland, Stephen D Dertinger

Environ Mol Mutagen· August 2016

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Comparison of in vitro and in vivo clastogenic potency based on benchmark dose analysis of flow cytometric micronucleus data.
Jeffrey C Bemis, John W Wills, Steven M Bryce, Dorothea K Torous, Stephen D Dertinger

Mutagenesis· May 2016

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Flow cytometric evaluation of the contribution of ionic silver to genotoxic potential of nanosilver in human liver HepG2 and colon Caco2 cells.
Saura C Sahu, Joyce Njoroge, Steven M Bryce, Jiwen Zheng, John Ihrie

J Appl Toxicol· April 2016

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Genotoxic mode of action predictions from a multiplexed flow cytometric assay and a machine learning approach.
Steven M Bryce, Derek T Bernacki, Jeffrey C Bemis, Stephen D Dertinger

Environ Mol Mutagen· April 2016

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ACKR4 on Stromal Cells Scavenges CCL19 To Enable CCR7-Dependent Trafficking of APCs from Inflamed Skin to Lymph Nodes.
Steven A Bryce, Ruairi A M Wilson, Eleanor M Tiplady, Darren L Asquith, Shannon K Bromley

J Immunol· April 2016

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Mouse Pig-a and micronucleus assays respond to N-ethyl-N-nitrosourea, benzo[a]pyrene, and ethyl carbamate, but not pyrene or methyl carbamate.
Carson Labash, Svetlana L Avlasevich, Kristine Carlson, Ariel Berg, Dorothea K Torous, Steven M Bryce

Environ Mol Mutagen· January 2016

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Best practices for application of attachment cells to in vitro micronucleus assessment by flow cytometry.
Jeffrey C Bemis, Steven M Bryce, Marlies Nern, Marian Raschke, Andreas Sutter

Mutat Res Genet Toxicol Environ Mutagen· January 2016

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