Publications by authors named "Stuart Cain"

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Chronic pregabalin treatment protects against spreading depolarization and alters hippocampal synaptic characteristics in a model of familial hemiplegic migraine-type 1.
Stuart M Cain, Sascha R A Alles, Ray Gopaul, Louis-Philippe Bernier, Andrew C Yung

Mol Brain· November 2023

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Image-Based Dosimetry in Dogs and Cross-Reactivity with Human Tissues of IGF2R-Targeting Human Antibody.
Kevin J H Allen, Ohyun Kwon, Matthew R Hutcheson, Joseph J Grudzinski, Stuart M Cain

Pharmaceuticals (Basel)· July 2023

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ADAMTS6 cleaves the large latent TGFβ complex and increases the mechanotension of cells to activate TGFβ.
Stuart A Cain, Steven Woods, Mukti Singh, Susan J Kimber, Clair Baldock

Matrix Biol· December 2022

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The type 1 cannabinoid receptor positive allosteric modulators GAT591 and GAT593 reduce spike-and-wave discharges in Genetic Absence Epilepsy Rats from Strasbourg.
Dan L McElroy, Andrew J Roebuck, Quentin Greba, Sumanta Garai, Asher L Brandt, Stuart M Cain

IBRO Neurosci Rep· June 2022

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Development of human cartilage circadian rhythm in a stem cell-chondrogenesis model.
Mark A Naven, Leo A H Zeef, Shiyang Li, Paul A Humphreys, Christopher A Smith, Stuart Cain

Theranostics· June 2022

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SIRT1 activity orchestrates ECM expression during hESC-chondrogenic differentiation.
Christopher A Smith, Paul A Humphreys, Nicola Bates, Mark A Naven, Stuart A Cain

FASEB J· May 2022

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Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.
Timothy J Mead, Daniel R Martin, Lauren W Wang, Stuart A Cain, Cagri Gulec

Elife· May 2022

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Latent TGFβ complexes are transglutaminase cross-linked to fibrillin to facilitate TGFβ activation.
Michael P Lockhart-Cairns, Stuart A Cain, Rana Dajani, Ruth Steer, Jennifer Thomson

Matrix Biol· March 2022

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Dissociable changes in spike and wave discharges following exposure to injected cannabinoids and smoked cannabis in Genetic Absence Epilepsy Rats from Strasbourg.
Andrew J Roebuck, Quentin Greba, Timothy J Onofrychuk, Dan L McElroy, Thaísa M Sandini, Stuart M Cain

Eur J Neurosci· February 2022

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Hyperexcitable superior colliculus and fatal brainstem spreading depolarization in a model of Sudden Unexpected Death in Epilepsy.
Stuart M Cain, Louis-Philippe Bernier, Yiming Zhang, Andrew C Yung, Jennifer Kass

Brain Commun· January 2022

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Delineation of a new fibrillin-2-opathy with evidence for a role of in the pathogenesis of carpal tunnel syndrome.
Silke Peeters, Arne Decramer, Stuart Alan Cain, Peter Houpt, Frederik Verstreken

J Med Genet· November 2021

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Autosomal Recessive Cutis Laxa 1C Mutations Disrupt the Structure and Interactions of Latent TGFβ Binding Protein-4.
Yasmene F Alanazi, Michael P Lockhart-Cairns, Stuart A Cain, Thomas A Jowitt, Anthony S Weiss

Front Genet· September 2021

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Positive allosteric modulation of type 1 cannabinoid receptors reduces spike-and-wave discharges in Genetic Absence Epilepsy Rats from Strasbourg.
Andrew J Roebuck, Quentin Greba, Anna-Maria Smolyakova, Mariam Alaverdashvili, Wendie N Marks, Stuart M Cain

Neuropharmacology· June 2021

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Regulation of TGFβ Signalling by TRPV4 in Chondrocytes.
Steven Woods, Paul A Humphreys, Nicola Bates, Sophie Alice Richardson, Shweta Yogesh Kuba, Stuart A Cain

Cells· March 2021

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Tropoelastin and Elastin Assembly.
Jazmin Ozsvar, Chengeng Yang, Stuart A Cain, Clair Baldock, Anna Tarakanova

Front Bioeng Biotechnol· February 2021

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Optogenetic Control of the BMP Signaling Pathway.
Paul A Humphreys, Steven Woods, Christopher A Smith, Nicola Bates, Stuart A Cain

ACS Synth Biol· November 2020

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Molecular Cloning, Lentiviral Transduction, and Expression of Recombinant ADAMTSL2 and ADAMTSL4.
Mukti Singh, Stuart A Cain, Clair Baldock

Methods Mol Biol· April 2020

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Pregabalin as a Pain Therapeutic: Beyond Calcium Channels.
Sascha R A Alles, Stuart M Cain, Terrance P Snutch

Front Cell Neurosci· April 2020

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The role of fibrillin and microfibril binding proteins in elastin and elastic fibre assembly.
Alan R F Godwin, Mukti Singh, Michael P Lockhart-Cairns, Yasmene F Alanazi, Stuart A Cain

Matrix Biol· November 2019

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Patient-Specific iPSC Model of a Genetic Vascular Dementia Syndrome Reveals Failure of Mural Cells to Stabilize Capillary Structures.
Joseph Kelleher, Adam Dickinson, Stuart Cain, Yanhua Hu, Nicola Bates

Stem Cell Reports· November 2019

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The X-Linked Intellectual Disability Gene Zdhhc9 Is Essential for Dendrite Outgrowth and Inhibitory Synapse Formation.
Jordan J Shimell, Bhavin S Shah, Stuart M Cain, Samrat Thouta, Naila Kuhlmann

Cell Rep· November 2019

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The T-type calcium channel blocker Z944 reduces conditioned fear in Genetic Absence Epilepsy Rats from Strasbourg and the non-epileptic control strain.
Wendie N Marks, Nadine K Zabder, Quentin Greba, Stuart M Cain, Terrance P Snutch

Eur J Neurosci· September 2019

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The T-type calcium channel antagonist, Z944, alters social behavior in Genetic Absence Epilepsy Rats from Strasbourg.
Wendie N Marks, Nadine K Zabder, Stuart M Cain, Terrance P Snutch, John G Howland

Behav Brain Res· April 2019

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Effect of Topography and Physical Stimulus on hMSC Phenotype Using a 3D In Vitro Model.
Deepak Kumar, Stuart A Cain, Lucy A Bosworth

Nanomaterials (Basel)· April 2019

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Brainstem spreading depolarization and cortical dynamics during fatal seizures in Cacna1a S218L mice.
Inge C M Loonen, Nico A Jansen, Stuart M Cain, Maarten Schenke, Rob A Voskuyl

Brain· February 2019

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