Publications by authors named "Stuart Farrow"

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Pancreatic CAF-Derived Autotaxin Drives Autocrine CTGF Expression to Modulate Protumorigenic Signaling.
Fanny Volat, Ragini Medhi, Lauren Z Maggs, Marcel A Deken, Alice Price, Stuart Farrow

Mol Cancer Ther· February 2025

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MAP3K8 is a potential therapeutic target in airway epithelial inflammation.
Chih-Yung Chiu, Saffron A G Willis-Owen, Kenny C C Wong, Stuart N Farrow, William O C Cookson

J Inflamm (Lond)· July 2024

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Glucocorticoids impair type I IFN signalling and enhance rhinovirus replication.
Andrea Marcellini, Dawid Swieboda, Anabel Guedán, Stuart N Farrow, Paolo Casolari

Eur J Pharmacol· February 2021

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A cell-based bioluminescence assay reveals dose-dependent and contextual repression of AP-1-driven gene expression by BACH2.
Panagiota Vardaka, Teresa Lozano, Christopher Bot, Jonathan Ellery, Sarah K Whiteside, Stuart Farrow

Sci Rep· November 2020

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Functional Genomics for Target Identification.
Davide Gianni, Stuart Farrow

SLAS Discov· July 2020

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Death Receptor 3 regulates distinct pathological attributes of acute versus chronic murine allergic lung inflammation.
Ravinder Kaur Singh, William Victor Perks, Jason Peter Twohig, Emma J Kidd, Kenneth Broadley, Stuart N Farrow

Cell Immunol· October 2017

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PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis.
Katherine Martin, James Pritchett, Jessica Llewellyn, Aoibheann F Mullan, Varinder S Athwal, Stuart Farrow

Nat Commun· August 2016

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Identification of benzopyrone as a common structural feature in compounds with anti-inflammatory activity in a zebrafish phenotypic screen.
Anne L Robertson, Nikolay V Ogryzko, Katherine M Henry, Catherine A Loynes, Matthew J Foulkes, Stuart N Farrow

Dis Model Mech· June 2016

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Glucocorticoid receptor regulates accurate chromosome segregation and is associated with malignancy.
Laura C Matthews, Andrew A Berry, David J Morgan, Toryn M Poolman, Kerstin Bauer, Stuart N Farrow

Proc Natl Acad Sci U S A· April 2015

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An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action.
Julie Gibbs, Louise Ince, Laura Matthews, Junjie Mei, Thomas Bell, Stuart Farrow

Nat Med· August 2014

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The methyltransferase WBSCR22/Merm1 enhances glucocorticoid receptor function and is regulated in lung inflammation and cancer.
Maryam Jangani, Toryn M Poolman, Laura Matthews, Nan Yang, Stuart N Farrow

J Biol Chem· March 2014

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Serum and glucocorticoid-regulated kinase 1 regulates neutrophil clearance during inflammation resolution.
Joseph Burgon, Anne L Robertson, Pranvera Sadiku, Xingang Wang, Edward Hooper-Greenhill, Stuart N Farrow

J Immunol· February 2014

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A zebrafish compound screen reveals modulation of neutrophil reverse migration as an anti-inflammatory mechanism.
Anne L Robertson, Geoffrey R Holmes, Aleksandra N Bojarczuk, Joseph Burgon, Catherine A Loynes, Stuart N Farrow

Sci Transl Med· February 2014

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The circadian clock and asthma.
Hannah J Durrington, Stuart N Farrow, Andrew S Loudon, David W Ray

Thorax· January 2014

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Pin1 promotes GR transactivation by enhancing recruitment to target genes.
Toryn M Poolman, Stuart N Farrow, Laura Matthews, Andrew S Loudon, David W Ray

Nucleic Acids Res· October 2013

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A ligand-specific kinetic switch regulates glucocorticoid receptor trafficking and function.
Peter J Trebble, James M Woolven, Ken A Saunders, Karen D Simpson, Stuart N Farrow

J Cell Sci· July 2013

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Optimized chemical probes for REV-ERBα.
Ryan P Trump, Stefano Bresciani, Anthony W J Cooper, James P Tellam, Justyna Wojno, Stuart N Farrow

J Med Chem· June 2013

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The importance of chronobiology to drug discovery.
Stuart N Farrow, Roberto Solari, Timothy M Willson

Expert Opin Drug Discov· July 2012

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The nuclear receptor REV-ERBα mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines.
Julie E Gibbs, John Blaikley, Stephen Beesley, Laura Matthews, Karen D Simpson, Stuart N Farrow

Proc Natl Acad Sci U S A· January 2012

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Transcriptomic analyses of murine resolution-phase macrophages.
Melanie J Stables, Sonia Shah, Evelyn B Camon, Ruth C Lovering, Justine Newson, Stuart Farrow

Blood· December 2011

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Treatment with a peroxisomal proliferator activated receptor gamma agonist has a modest effect in the allergen challenge model in asthma: a randomised controlled trial.
Duncan B Richards, Philippe Bareille, Emma L Lindo, Dean Quinn, Stuart N Farrow

Respir Med· May 2010

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A new strategy for the identification of novel molecules with targeted proresolution of inflammation properties.
Roberta A Navarro-Xavier, Justine Newson, Vera Lucia Flor Silveira, Stuart N Farrow, Derek W Gilroy

J Immunol· February 2010

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The effects of dexamethasone on cigarette smoke induced gene expression changes in COPD macrophages.
Lauren M Kent, Steve M Fox, Stuart N Farrow, Dave Singh

Int Immunopharmacol· January 2010

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Inhibition of lipopolysaccharide-stimulated chronic obstructive pulmonary disease macrophage inflammatory gene expression by dexamethasone and the p38 mitogen-activated protein kinase inhibitor N-cyano-N'-(2-{[8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-7-oxo-7,8-dihydropyrido[2,3-d] pyrimidin-2-yl]amino}ethyl)guanidine (SB706504).
Lauren M Kent, Lucy J C Smyth, Jonathan Plumb, Chris L Clayton, Steve M Fox, Stuart N Farrow

J Pharmacol Exp Ther· February 2009

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Ligand modulation of REV-ERBalpha function resets the peripheral circadian clock in a phasic manner.
Qing Jun Meng, Andrew McMaster, Stephen Beesley, Wei Qun Lu, Julie Gibbs, Stuart Farrow

J Cell Sci· November 2008

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