Publications by authors named "Subhendu Das"

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A tumorigenesis threshold for endogenous Myc revealed by dosage-compensation for Myc-haploinsufficiency in the absence of p53.
Xiaozhong Bao, Zied Abdullaev, Subhendu K Das, Valerie Zgonc, Kris Ylaya

bioRxiv· July 2025

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Excessive MYC-topoisome activity triggers acute DNA damage, MYC degradation, and replacement by a p53-topoisome.
Subhendu K Das, Sharmistha Karmakar, Harish Venkatachalapathy, Rajiv Kumar Jha, Eric Batchelor

Mol Cell· November 2024

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Self-assembly of promoter DNA and RNA Pol II machinery into transcriptionally active biomolecular condensates.
Brian A Lewis, Subhendu Kumar Das, Rajiv Kumar Jha, David Levens

Sci Adv· October 2023

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MYC: a complex problem.
Subhendu K Das, Brian A Lewis, David Levens

Trends Cell Biol· March 2023

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Novel Pyrido[2',1':2,3]imidazo[4,5-]quinoline Derivative Selectively Poisons Bisubunit Topoisomerase 1 to Inhibit the Antimony-Resistant Infection .
Srijita Paul Chowdhuri, Shiv Dhiman, Subhendu K Das, Neha Meena, Sonali Das, Benu Brata Das

J Med Chem· March 2023

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TDP1 knockout Leishmania donovani accumulate topoisomerase 1-linked DNA damage and are hypersensitive to clinically used antileishmanial drugs.
Somenath Roy Chowdhury, Subhendu K Das, Bijoylaxmi Banerjee, Srijita Paul Chowdhuri, Hemanta K Majumder, Benu Brata Das

FASEB J· April 2022

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MYC assembles and stimulates topoisomerases 1 and 2 in a "topoisome".
Subhendu K Das, Vladislav Kuzin, Donald P Cameron, Suzanne Sanford, Rajiv Kumar Jha

Mol Cell· January 2022

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Development of a metabolically stable topoisomerase I poison as anticancer agent.
Biswajit Kundu, Dipayan Sarkar, Srijita Paul Chowdhuri, Sourav Pal, Subhendu K Das, Benu Brata Das

Eur J Med Chem· September 2020

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Dissecting transcriptional amplification by MYC.
Zuqin Nie, Chunhua Guo, Subhendu K Das, Carson C Chow, Eric Batchelor

Elife· July 2020

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Discovery and Mechanistic Study of Tailor-Made Quinoline Derivatives as Topoisomerase 1 Poison with Potent Anticancer Activity.
Biswajit Kundu, Subhendu K Das, Srijita Paul Chowdhuri, Sourav Pal, Dipayan Sarkar, Benu Brata Das

J Med Chem· April 2019

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Studies toward the synthesis of strevertenes A and G: stereoselective construction of C-C segments of the molecules.
Tapan Kumar Kuilya, Subhendu Das, Dhiman Saha, Rajib Kumar Goswami

Org Biomol Chem· November 2018

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PRMT5-mediated arginine methylation of TDP1 for the repair of topoisomerase I covalent complexes.
Ishita Rehman, Suparna M Basu, Subhendu K Das, Sangheeta Bhattacharjee, Arijit Ghosh, Benu Brata Das

Nucleic Acids Res· June 2018

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VEGF may contribute to macrophage recruitment and M2 polarization in the decidua.
Karen C Wheeler, Manoj K Jena, Bhola S Pradhan, Neha Nayak, Subhendu Das

PLoS One· March 2018

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Neutral Porphyrin Derivative Exerts Anticancer Activity by Targeting Cellular Topoisomerase I (Top1) and Promotes Apoptotic Cell Death without Stabilizing Top1-DNA Cleavage Complexes.
Subhendu K Das, Arijit Ghosh, Srijita Paul Chowdhuri, Nyancy Halder, Ishita Rehman, Benu Brata Das

J Med Chem· February 2018

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Total synthesis of marine natural products separacenes A and B.
Subhendu Das, Rajib Kumar Goswami

Org Biomol Chem· June 2017

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Poly(ADP-ribose) polymers regulate DNA topoisomerase I (Top1) nuclear dynamics and camptothecin sensitivity in living cells.
Subhendu K Das, Ishita Rehman, Arijit Ghosh, Souvik Sengupta, Papiya Majumdar, Benu Brata Das

Nucleic Acids Res· September 2016

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Design, synthesis and evaluation of thiohydantoin derivatives as potent topoisomerase I (Top1) inhibitors with anticancer activity.
Papiya Majumdar, Chandramohan Bathula, Suparna M Basu, Subhendu K Das, Rahul Agarwal, Benu Brata Das

Eur J Med Chem· September 2015

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Asymmetric Total Synthesis of Bioactive Natural Lipid Mycalol.
Subhendu Das, Tapan Kumar Kuilya, Rajib Kumar Goswami

J Org Chem· June 2015

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Identification of human cytomegalovirus genes important for biogenesis of the cytoplasmic virion assembly complex.
Subhendu Das, Daniel A Ortiz, Stephen J Gurczynski, Fatin Khan, Philip E Pellett

J Virol· August 2014

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PARP1-TDP1 coupling for the repair of topoisomerase I-induced DNA damage.
Benu Brata Das, Shar-yin N Huang, Junko Murai, Ishita Rehman, Jean-Christophe Amé, Subhendu K Das

Nucleic Acids Res· April 2014

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Deletion of the human cytomegalovirus US17 gene increases the ratio of genomes per infectious unit and alters regulation of immune and endoplasmic reticulum stress response genes at early and late times after infection.
Stephen J Gurczynski, Subhendu Das, Philip E Pellett

J Virol· February 2014

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Spatial relationships between markers for secretory and endosomal machinery in human cytomegalovirus-infected cells versus those in uninfected cells.
Subhendu Das, Philip E Pellett

J Virol· June 2011

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Three-dimensional structure of the human cytomegalovirus cytoplasmic virion assembly complex includes a reoriented secretory apparatus.
Subhendu Das, Amit Vasanji, Philip E Pellett

J Virol· November 2007

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Members of the HCMV US12 family of predicted heptaspanning membrane proteins have unique intracellular distributions, including association with the cytoplasmic virion assembly complex.
Subhendu Das, Philip E Pellett

Virology· May 2007

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Fine needle aspiration biopsy in the management of tumours in superolateral quadrant of orbit.
Anita Banerjee, Dipanwita Nag, Subhendu Das, Pradyot Narayan Biswas, Asim Ghosh

J Indian Med Assoc· July 2006

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