Publications by authors named "Susan O Sharrow"

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Pillars Article: Coreceptor Reversal in the Thymus: Signaled CD4+8+ Thymocytes Initially Terminate CD8 Transcription Even When Differentiating into CD8+ T Cells. Immunity. 2000. 13: 59-71.
Enrico Brugnera, Avinash Bhandoola, Ricardo Cibotti, Qing Yu, Terry I Guinter, Susan O Sharrow

J Immunol· March 2016

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Let-7 microRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function.
Leonid A Pobezinsky, Ruth Etzensperger, Susanna Jeurling, Amala Alag, Tejas Kadakia, Susan O Sharrow

Nat Immunol· May 2015

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T cell-B cell thymic cross-talk: maintenance and function of thymic B cells requires cognate CD40-CD40 ligand interaction.
Chiharu Fujihara, Joy A Williams, Masashi Watanabe, Hyein Jeon, Susan O Sharrow

J Immunol· December 2014

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Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways.
Joy A Williams, Jingjing Zhang, Hyein Jeon, Takeshi Nitta, Izumi Ohigashi, Susan O Sharrow

J Immunol· January 2014

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Lck availability during thymic selection determines the recognition specificity of the T cell repertoire.
François Van Laethem, Anastasia N Tikhonova, Leonid A Pobezinsky, Xuguang Tai, Motoko Y Kimura, Susan O Sharrow

Cell· September 2013

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Basis of CTLA-4 function in regulatory and conventional CD4(+) T cells.
Xuguang Tai, François Van Laethem, Leonid Pobezinsky, Terry Guinter, Susan O Sharrow

Blood· May 2012

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Upregulation of CD4 expression during MHC class II-specific positive selection is essential for error-free lineage choice.
Sophia D Sarafova, Francois Van Laethem, Stanley Adoro, Terry Guinter, Susan O Sharrow

Immunity· September 2009

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Deletion of CD4 and CD8 coreceptors permits generation of alphabetaT cells that recognize antigens independently of the MHC.
François Van Laethem, Sophia D Sarafova, Jung-Hyun Park, Xuguang Tai, Leonid Pobezinsky, Susan O Sharrow

Immunity· November 2007

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Coreceptor signal strength regulates positive selection but does not determine CD4/CD8 lineage choice in a physiologic in vivo model.
Batu Erman, Amala S Alag, Oyvind Dahle, François van Laethem, Sophia D Sarafova, Susan O Sharrow

J Immunol· November 2006

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Modulation of coreceptor transcription during positive selection dictates lineage fate independently of TCR/coreceptor specificity.
Sophia D Sarafova, Batu Erman, Qing Yu, François Van Laethem, Terry Guinter, Susan O Sharrow

Immunity· July 2005

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A dose effect of IL-7 on thymocyte development.
Nahed El Kassar, Philip J Lucas, David B Klug, Monica Zamisch, Melinda Merchant, Susan O Sharrow

Blood· September 2004

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Exogenous IL-7 increases recent thymic emigrants in peripheral lymphoid tissue without enhanced thymic function.
Yu-Waye Chu, Sarfraz A Memon, Susan O Sharrow, Frances T Hakim, Michael Eckhaus

Blood· August 2004

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Unraveling a revealing paradox: Why major histocompatibility complex I-signaled thymocytes "paradoxically" appear as CD4+8lo transitional cells during positive selection of CD8+ T cells.
Remy Bosselut, Terry I Guinter, Susan O Sharrow, Alfred Singer

J Exp Med· June 2003

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In vitro evidence that cytokine receptor signals are required for differentiation of double positive thymocytes into functionally mature CD8+ T cells.
Qing Yu, Batu Erman, Avinash Bhandoola, Susan O Sharrow, Alfred Singer

J Exp Med· February 2003

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Overview of flow cytometry.
Susan O Sharrow

Curr Protoc Immunol· November 2002

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CD40 ligand functions non-cell autonomously to promote deletion of self-reactive thymocytes.
Joy A Williams, Susan O Sharrow, Anthony J Adams, Richard J Hodes

J Immunol· March 2002

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