Publications by authors named "Terry Guinter"

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How autoreactive thymocytes differentiate into regulatory versus effector CD4 T cells after avoiding clonal deletion.
Xuguang Tai, Alyssa Indart, Mirelle Rojano, Jie Guo, Nicolai Apenes, Terry Guinter

Nat Immunol· April 2023

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Reversal of the T cell immune system reveals the molecular basis for T cell lineage fate determination in the thymus.
Miho Shinzawa, E Ashley Moseman, Selamawit Gossa, Yasuko Mano, Abhisek Bhattacharya, Terry Guinter

Nat Immunol· May 2022

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Novel MHC-Independent αβTCRs Specific for CD48, CD102, and CD155 Self-Proteins and Their Selection in the Thymus.
François Van Laethem, Ingrid Saba, Jinghua Lu, Abhisek Bhattacharya, Xuguang Tai, Terry I Guinter

Front Immunol· April 2021

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E-protein-regulated expression of CXCR4 adheres preselection thymocytes to the thymic cortex.
Tejas Kadakia, Xuguang Tai, Michael Kruhlak, Jan Wisniewski, Il-Young Hwang, Terry I Guinter

J Exp Med· August 2019

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Identification of lineage-specifying cytokines that signal all CD8-cytotoxic-lineage-fate 'decisions' in the thymus.
Ruth Etzensperger, Tejas Kadakia, Xuguang Tai, Amala Alag, Terry I Guinter

Nat Immunol· November 2017

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Timing and duration of MHC I positive selection signals are adjusted in the thymus to prevent lineage errors.
Motoko Y Kimura, Julien Thomas, Xuguang Tai, Terry I Guinter, Miho Shinzawa

Nat Immunol· December 2016

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Pillars Article: Coreceptor Reversal in the Thymus: Signaled CD4+8+ Thymocytes Initially Terminate CD8 Transcription Even When Differentiating into CD8+ T Cells. Immunity. 2000. 13: 59-71.
Enrico Brugnera, Avinash Bhandoola, Ricardo Cibotti, Qing Yu, Terry I Guinter

J Immunol· March 2016

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Let-7 microRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function.
Leonid A Pobezinsky, Ruth Etzensperger, Susanna Jeurling, Amala Alag, Tejas Kadakia, Terry I Guinter

Nat Immunol· May 2015

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Lck availability during thymic selection determines the recognition specificity of the T cell repertoire.
François Van Laethem, Anastasia N Tikhonova, Leonid A Pobezinsky, Xuguang Tai, Motoko Y Kimura, Terry I Guinter

Cell· September 2013

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Foxp3 transcription factor is proapoptotic and lethal to developing regulatory T cells unless counterbalanced by cytokine survival signals.
Xuguang Tai, Batu Erman, Amala Alag, Jie Mu, Motoko Kimura, Terry Guinter

Immunity· June 2013

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IL-7 signaling must be intermittent, not continuous, during CD8⁺ T cell homeostasis to promote cell survival instead of cell death.
Motoko Y Kimura, Leonid A Pobezinsky, Terry I Guinter, Julien Thomas, Anthony Adams

Nat Immunol· February 2013

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Basis of CTLA-4 function in regulatory and conventional CD4(+) T cells.
Xuguang Tai, François Van Laethem, Leonid Pobezinsky, Terry Guinter, Susan O Sharrow

Blood· May 2012

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The general transcription factor TAF7 is essential for embryonic development but not essential for the survival or differentiation of mature T cells.
Anne Gegonne, Xuguang Tai, Jinghui Zhang, Gang Wu, Jianjian Zhu, Terry Guinter

Mol Cell Biol· May 2012

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αβ T cell receptors that do not undergo major histocompatibility complex-specific thymic selection possess antibody-like recognition specificities.
Anastasia N Tikhonova, François Van Laethem, Ken-ichi Hanada, Jinghua Lu, Leonid A Pobezinsky, Terry I Guinter

Immunity· January 2012

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Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells.
Jung-Hyun Park, Stanley Adoro, Terry Guinter, Batu Erman, Amala S Alag

Nat Immunol· March 2010

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Upregulation of CD4 expression during MHC class II-specific positive selection is essential for error-free lineage choice.
Sophia D Sarafova, Francois Van Laethem, Stanley Adoro, Terry Guinter, Susan O Sharrow

Immunity· September 2009

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Deletion of CD4 and CD8 coreceptors permits generation of alphabetaT cells that recognize antigens independently of the MHC.
François Van Laethem, Sophia D Sarafova, Jung-Hyun Park, Xuguang Tai, Leonid Pobezinsky, Terry I Guinter

Immunity· November 2007

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Coreceptor signal strength regulates positive selection but does not determine CD4/CD8 lineage choice in a physiologic in vivo model.
Batu Erman, Amala S Alag, Oyvind Dahle, François van Laethem, Sophia D Sarafova, Terry I Guinter

J Immunol· November 2006

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Modulation of coreceptor transcription during positive selection dictates lineage fate independently of TCR/coreceptor specificity.
Sophia D Sarafova, Batu Erman, Qing Yu, François Van Laethem, Terry Guinter

Immunity· July 2005

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Defined alphabeta T cell receptors with distinct ligand specificities do not require those ligands to signal double negative thymocyte differentiation.
Batu Erman, Terry I Guinter, Alfred Singer

J Exp Med· June 2004

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Unraveling a revealing paradox: Why major histocompatibility complex I-signaled thymocytes "paradoxically" appear as CD4+8lo transitional cells during positive selection of CD8+ T cells.
Remy Bosselut, Terry I Guinter, Susan O Sharrow, Alfred Singer

J Exp Med· June 2003

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