Publications by authors named "Teddy Yang"

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iPSC-induced neurons with the V337M MAPT mutation are selectively vulnerable to caspase-mediated cleavage of tau and apoptotic cell death.
Panos Theofilas, Chao Wang, David Butler, Dulce O Morales, Cathrine Petersen, Teddy Yang

Mol Cell Neurosci· September 2024

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Safety and efficacy of an anti-human APC antibody for prophylaxis of congenital factor deficiencies in preclinical models.
Miao Jiang, Fei Yang, Yizhi Jiang, Lu Cheng, Jingjing Han, Teddy Tat Chi Yang

Blood· September 2023

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Characterization of 405B8H3(D-E), a newly engineered high affinity chimeric LAG-3 antibody with potent antitumor activity.
Xiaoxuan Lan, Teddy Tat Chi Yang, Yinghui Wang, Baoyuan Qu, Shaofeng Rong

FEBS Open Bio· July 2023

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High-throughput optofluidic screening of single B cells identifies novel cross-reactive antibodies as inhibitors of uPAR with antibody-dependent effector functions.
André Luiz Lourenço, Shih-Wei Chuo, Markus F Bohn, Byron Hann, Shireen Khan, Teddy Yang

MAbs· March 2023

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Development and characterization of a novel human CD137 agonistic antibody with anti-tumor activity and a good safety profile in non-human primates.
Yingying Gao, Teddy Yang, Hu Liu, Ningning Song, Chaohui Dai

FEBS Open Bio· December 2022

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Developing high-affinity decoy receptors to treat multiple myeloma and diffuse large B cell lymphoma.
Yu Rebecca Miao, Kaushik Thakkar, Can Cenik, Dadi Jiang, Kazue Mizuno, Teddy Tat Chi Yang

J Exp Med· September 2022

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Caspase-6-cleaved tau is relevant in Alzheimer's disease and marginal in four-repeat tauopathies: Diagnostic and therapeutic implications.
Panos Theofilas, Antonia M H Piergies, Ian Oh, Yoo Bin Lee, Song Hua Li, Teddy Yang

Neuropathol Appl Neurobiol· August 2022

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Development of a fully human anti-GITR antibody with potent antitumor activity using H2L2 mice.
Qiuli Tong, Hu Liu, Qianqian Qi, Chaohui Dai, Teddy Yang

FEBS Open Bio· August 2022

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Neutralization of PD-L2 is Essential for Overcoming Immune Checkpoint Blockade Resistance in Ovarian Cancer.
Yu Rebecca Miao, Kaushik N Thakkar, Jin Qian, Mihalis S Kariolis, Wei Huang, Teddy Tat Chi Yang

Clin Cancer Res· August 2021

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Generation and characterization of a high-affinity chimeric anti-OX40 antibody with potent antitumor activity.
Yongli Yang, Xiaojuan Chai, Wenfang Xin, Dongxu Wang, Chaohui Dai, Teddy Yang

FEBS Lett· June 2021

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Preclinical efficacy and toxicity studies of a highly specific chimeric anti-CD47 antibody.
Zhiqiang Xu, Jing Gao, Jingyun Yao, Teddy Yang, Dongxu Wang

FEBS Open Bio· March 2021

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Therapeutic Development of Immune Checkpoint Inhibitors.
Jilin Wang, Teddy Yang, Jie Xu

Adv Exp Med Biol· April 2020

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Study of the interactions of a novel monoclonal antibody, mAb059c, with the hPD-1 receptor.
Jingxian Liu, Guiqun Wang, Liu Liu, Runjie Wu, Yi Wu, Teddy Tat Chi Yang

Sci Rep· November 2019

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Perinuclear Anchoring of H3K9-Methylated Chromatin Stabilizes Induced Cell Fate in C. elegans Embryos.
Adriana Gonzalez-Sandoval, Benjamin D Towbin, Veronique Kalck, Daphne S Cabianca, Dimos Gaidatzis, Teddy Yang

Cell· December 2015

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NSD2 is recruited through its PHD domain to oncogenic gene loci to drive multiple myeloma.
Zheng Huang, Haiping Wu, Shannon Chuai, Fiona Xu, Feng Yan, Teddy Yang

Cancer Res· October 2013

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Ablation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterases.
Hee Yun Suk, Chen Zhou, Teddy T C Yang, Hong Zhu, Raymond Y L Yu, XiaoYong Yang

J Biol Chem· February 2013

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Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation.
Wei Qi, HoMan Chan, Lin Teng, Ling Li, Shannon Chuai, Teddy Yang

Proc Natl Acad Sci U S A· December 2012

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Elucidating protein: DNA complex by oligonucleotide DNA affinity purification.
Teddy T C Yang, Chi-Wing Chow

Methods Mol Biol· March 2012

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CD40 pathway activation status predicts response to CD40 therapy in diffuse large B cell lymphoma.
Bart Burington, Peng Yue, Xiaoyan Shi, Ranjana Advani, Jeffrey T Lau, Teddy T C Yang

Sci Transl Med· March 2011

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Evolutionarily conserved role of calcineurin in phosphodegron-dependent degradation of phosphodiesterase 4D.
Hong Zhu, Hee Yun Suk, Raymond Y L Yu, Deborah Brancho, Opeyemi Olabisi, Teddy T C Yang, XiaoYong Yang

Mol Cell Biol· September 2010

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Regulation of transcription factor NFAT by ADP-ribosylation.
Opeyemi A Olabisi, Noemi Soto-Nieves, Edward Nieves, Teddy T C Yang, Xiaoyong Yang

Mol Cell Biol· May 2008

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Integration of protein kinases mTOR and extracellular signal-regulated kinase 5 in regulating nucleocytoplasmic localization of NFATc4.
Teddy T C Yang, Raymond Y L Yu, Anissa Agadir, Guo-Jian Gao, Roberto Campos-Gonzalez

Mol Cell Biol· May 2008

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Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition.
Xiao Yong Yang, Teddy T C Yang, William Schubert, Stephen M Factor, Chi-Wing Chow

Dev Biol· March 2007

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Role of transcription factor NFAT in glucose and insulin homeostasis.
Teddy T C Yang, Hee Yun Suk, Xiaoyong Yang, Opeyemi Olabisi, Raymond Y L Yu

Mol Cell Biol· October 2006

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Role of the CCAAT/enhancer-binding protein NFATc2 transcription factor cascade in the induction of secretory phospholipase A2.
Teddy T C Yang, Peter M U Ung, Mercedes Rincón, Chi-Wing Chow

J Biol Chem· April 2006

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