Publications by authors named "Terrance D Barrett"

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TMPRSS6 as a Therapeutic Target for Disorders of Erythropoiesis and Iron Homeostasis.
Tomas Ganz, Elizabeta Nemeth, Stefano Rivella, Paul Goldberg, Andrew R Dibble, Terrance D Barrett

Adv Ther· April 2023

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Effects of ibrutinib on in vitro platelet aggregation in blood samples from healthy donors and donors with platelet dysfunction.
Joi Ninomoto, Ahmad Mokatrin, Taisei Kinoshita, Carol Marimpietri, Terrance D Barrett

Hematology· December 2020

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Effects of Canagliflozin on Heart Failure Outcomes Associated With Preserved and Reduced Ejection Fraction in Type 2 Diabetes Mellitus.
Gemma A Figtree, Karin Rådholm, Terrance D Barrett, Vlado Perkovic, Kenneth W Mahaffey

Circulation· May 2019

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Beyond Traditional Structure-Based Drug Design: The Role of Iron Complexation, Strain, and Water in the Binding of Inhibitors for Hypoxia-Inducible Factor Prolyl Hydroxylase 2.
Scott D Bembenek, Hariharan Venkatesan, Hillary M Peltier, Mark D Rosen, Terrance D Barrett

ACS Omega· April 2019

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Canagliflozin and renal outcomes in type 2 diabetes: results from the CANVAS Program randomised clinical trials.
Vlado Perkovic, Dick de Zeeuw, Kenneth W Mahaffey, Greg Fulcher, Ngozi Erondu, Terrance D Barrett

Lancet Diabetes Endocrinol· September 2018

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Canagliflozin and Heart Failure in Type 2 Diabetes Mellitus: Results From the CANVAS Program.
Karin Rådholm, Gemma Figtree, Vlado Perkovic, Scott D Solomon, Kenneth W Mahaffey, Terrance D Barrett

Circulation· July 2018

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Prolyl hydroxylase inhibition corrects functional iron deficiency and inflammation-induced anaemia in rats.
Terrance D Barrett, Heather L Palomino, Theresa I Brondstetter, Kimon C Kanelakis, Xiaodong Wu

Br J Pharmacol· August 2015

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JNJ-26070109 [(R)4-bromo-N-[1-(2,4-difluoro-phenyl)-ethyl]-2-(quinoxaline-5-sulfonylamino)-benzamide]: a novel, potent, and selective cholecystokinin 2 receptor antagonist with good oral bioavailability.
Magda F Morton, Terrance D Barrett, Jamie Freedman, Lina Li, Michele C Rizzolio

J Pharmacol Exp Ther· July 2011

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Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935), a potent and selective hypoxia-inducible factor prolyl hydroxylase inhibitor.
Terrance D Barrett, Heather L Palomino, Theresa I Brondstetter, Kimon C Kanelakis, Xiaodong Wu

Mol Pharmacol· June 2011

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Targeting gastrin for the treatment of gastric acid related disorders and pancreatic cancer.
Magda Morton, Clodagh Prendergast, Terrance D Barrett

Trends Pharmacol Sci· April 2011

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Benzimidazole-2-pyrazole HIF Prolyl 4-Hydroxylase Inhibitors as Oral Erythropoietin Secretagogues.
Mark D Rosen, Hariharan Venkatesan, Hillary M Peltier, Scott D Bembenek, Kimon C Kanelakis, Terrance D Barrett

ACS Med Chem Lett· December 2010

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Discovery of the first known small-molecule inhibitors of heme-regulated eukaryotic initiation factor 2alpha (HRI) kinase.
Mark D Rosen, Craig R Woods, Steven D Goldberg, Michael D Hack, A Dawn Bounds, Terrance D Barrett

Bioorg Med Chem Lett· December 2009

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Anthranilic sulfonamide CCK1/CCK2 dual receptor antagonists II: tuning of receptor selectivity and in vivo efficacy.
Marna Pippel, Kristen Boyce, Hariharan Venkatesan, Victor K Phuong, Wen Yan, Terrance D Barrett

Bioorg Med Chem Lett· November 2009

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Characterization of a robust enzymatic assay for inhibitors of 2-oxoglutarate-dependent hydroxylases.
Kimon C Kanelakis, Heather L Palomino, Lina Li, Jiejun Wu, Wen Yan, Terrance D Barrett

J Biomol Screen· July 2009

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Discovery of potent cholecystokinin-2 receptor antagonists: elucidation of key pharmacophore elements by X-ray crystallographic and NMR conformational analysis.
Mark D Rosen, Michael D Hack, Brett D Allison, Victor K Phuong, Craig R Woods, Terrance D Barrett

Bioorg Med Chem· April 2008

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Effects of cyclooxygenase inhibition on canine coronary artery blood flow and thrombosis.
Ting-Ting Hong, Jinbao Huang, Terrance D Barrett, Benedict R Lucchesi

Am J Physiol Heart Circ Physiol· January 2008

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SAR studies of 1,5-diarylpyrazole-based CCK1 receptor antagonists.
Laurent Gomez, Michael D Hack, Kelly McClure, Clark Sehon, Liming Huang, Terrance D Barrett

Bioorg Med Chem Lett· December 2007

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Synthesis and solid-phase purification of anthranilic sulfonamides as CCK-2 ligands.
Craig R Woods, Michael D Hack, Brett D Allison, Victor K Phuong, Mark D Rosen, Terrance D Barrett

Bioorg Med Chem Lett· December 2007

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3-[5-(3,4-Dichloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyrazol-3-yl]-2-m-tolyl-propionate (JNJ-17156516), a novel, potent, and selective cholecystokinin 1 receptor antagonist: in vitro and in vivo pharmacological comparison with dexloxiglumide.
Magda F Morton, Terrance D Barrett, Wen Yan, Jamie M Freedman, Guy Lagaud

J Pharmacol Exp Ther· November 2007

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Synthesis and biological studies of novel 2-aminoalkylethers as potential antiarrhythmic agents for the conversion of atrial fibrillation.
Bertrand Plouvier, Gregory N Beatch, Grace L Jung, Alexander Zolotoy, Tao Sheng, Terrance D Barrett

J Med Chem· June 2007

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Obestatin reduces food intake and suppresses body weight gain in rodents.
Guy J Lagaud, Andy Young, Auzon Acena, Magda F Morton, Terrance D Barrett

Biochem Biophys Res Commun· May 2007

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Effect of sodium/hydrogen exchange inhibition on myocardial infarct size after coronary artery thrombosis and thrombolysis.
James K Hennan, Edward M Driscoll, Terrance D Barrett, Peter S Fischbach, Benedict R Lucchesi

Pharmacology· December 2006

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A novel, quantitative bio-assay for cholecystokinin type-1 receptor activity in the anaesthetised rat.
Jamie M Freedman, Terrance D Barrett, Nigel P Shankley

J Pharmacol Toxicol Methods· October 2006

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Pyrazole CCK(1) receptor antagonists. Part 2: SAR studies by solid-phase library synthesis and determination of Free-Wilson additivity.
Clark Sehon, Kelly McClure, Michael Hack, Magda Morton, Laurent Gomez, Terrance D Barrett

Bioorg Med Chem Lett· January 2006

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Pyrazole CCK(1) receptor antagonists. Part 1: Solution-phase library synthesis and determination of Free-Wilson additivity.
Kelly McClure, Michael Hack, Liming Huang, Clark Sehon, Magda Morton, Terrance D Barrett

Bioorg Med Chem Lett· January 2006

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