Publications by authors named "Terry D Crawford"

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Discovery of potent dihydro-oxazinoquinolinone inhibitors of GuaB for the treatment of tuberculosis.
Yuebiao Zhou, Ignacio Aliagas, Shumei Wang, Chun Sing Li, Zhiguo Liu, Terry D Crawford

Bioorg Med Chem Lett· March 2025

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Differential effects of inosine monophosphate dehydrogenase (IMPDH/GuaB) inhibition in and .
Yutian Peng, John G Moffat, Cory DuPai, Eric M Kofoed, Elizabeth Skippington, Terry D Crawford

J Bacteriol· October 2024

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GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1.
Alexander M Taylor, Chris Bailey, Lisa D Belmont, Robert Campbell, Nico Cantone, Terry D Crawford

J Med Chem· August 2022

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GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1-like.
Shumei Wang, Vickie Tsui, Terry D Crawford, James E Audia, Daniel J Burdick

J Med Chem· October 2018

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Design and synthesis of a biaryl series as inhibitors for the bromodomains of CBP/P300.
Kwong Wah Lai, F Anthony Romero, Vickie Tsui, Maureen H Beresini, Gladys de Leon Boenig, Terry D Crawford

Bioorg Med Chem Lett· January 2018

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A Unique Approach to Design Potent and Selective Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) Inhibitors.
Sarah M Bronner, Jeremy Murray, F Anthony Romero, Kwong Wah Lai, Vickie Tsui, Terry D Crawford

J Med Chem· December 2017

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Discovery of Small-Molecule Inhibitors of Ubiquitin Specific Protease 7 (USP7) Using Integrated NMR and in Silico Techniques.
Paola Di Lello, Richard Pastor, Jeremy M Murray, Robert A Blake, Frederick Cohen, Terry D Crawford

J Med Chem· December 2017

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GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP).
F Anthony Romero, Jeremy Murray, Kwong Wah Lai, Vickie Tsui, Brian K Albrecht, Terry D Crawford

J Med Chem· November 2017

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Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance.
Terry D Crawford, Steffan Vartanian, Alexandre Côté, Steve Bellon, Martin Duplessis

Bioorg Med Chem Lett· August 2017

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GNE-886: A Potent and Selective Inhibitor of the Cat Eye Syndrome Chromosome Region Candidate 2 Bromodomain (CECR2).
Terry D Crawford, James E Audia, Steve Bellon, Daniel J Burdick, Archana Bommi-Reddy

ACS Med Chem Lett· July 2017

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Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300.
Terry D Crawford, F Anthony Romero, Kwong Wah Lai, Vickie Tsui, Alexander M Taylor

J Med Chem· December 2016

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Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains.
Terry D Crawford, Vickie Tsui, E Megan Flynn, Shumei Wang, Alexander M Taylor

J Med Chem· June 2016

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Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637).
Alexander M Taylor, Alexandre Côté, Michael C Hewitt, Richard Pastor, Yves Leblanc, Terry D Crawford

ACS Med Chem Lett· May 2016

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Disrupting Acetyl-Lysine Recognition: Progress in the Development of Bromodomain Inhibitors.
F Anthony Romero, Alexander M Taylor, Terry D Crawford, Vickie Tsui, Alexandre Côté

J Med Chem· February 2016

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Structure-Based Design of GNE-495, a Potent and Selective MAP4K4 Inhibitor with Efficacy in Retinal Angiogenesis.
Chudi O Ndubaku, Terry D Crawford, Huifen Chen, Jason W Boggs, Joy Drobnick

ACS Med Chem Lett· August 2015

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Fragment-based identification and optimization of a class of potent pyrrolo[2,1-f][1,2,4]triazine MAP4K4 inhibitors.
Lan Wang, Mark Stanley, Jason W Boggs, Terry D Crawford, Brandon J Bravo

Bioorg Med Chem Lett· September 2014

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Discovery of selective 4-Amino-pyridopyrimidine inhibitors of MAP4K4 using fragment-based lead identification and optimization.
Terry D Crawford, Chudi O Ndubaku, Huifen Chen, Jason W Boggs, Brandon J Bravo

J Med Chem· April 2014

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