Publications by authors named "Tessa Simone"

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Inhibition of Rho-Associated Kinases ROCK1 and ROCK2 as a Therapeutic Strategy to Reactivate the Repressed Gene in Friedreich Ataxia.
Minggang Fang, Shahid Banday, Sara K Deibler, Tessa M Simone, Madison Coleman

J Neurosci· June 2025

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Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma.
Tianyi Ye, Alok K Mishra, Shahid Banday, Rui Li, Kai Hu, Tessa M Simone

Cell Rep· May 2024

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Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer.
Alok K Mishra, Tianyi Ye, Shahid Banday, Ritesh P Thakare, Chinh Tran-To Su, Tessa M Simone

Cell Rep· April 2024

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The histone H3K9 demethylase KDM3A promotes anoikis by transcriptionally activating pro-apoptotic genes BNIP3 and BNIP3L.
Victoria E Pedanou, Stéphane Gobeil, Sébastien Tabariès, Tessa M Simone, Lihua Julie Zhu

Elife· July 2016

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U2AF35(S34F) Promotes Transformation by Directing Aberrant ATG7 Pre-mRNA 3' End Formation.
Sung Mi Park, Jianhong Ou, Lynn Chamberlain, Tessa M Simone, Huan Yang

Mol Cell· May 2016

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Targeted Inhibition of PAI-1 Activity Impairs Epithelial Migration and Wound Closure Following Cutaneous Injury.
Tessa M Simone, Whitney M Longmate, Brian K Law, Paul J Higgins

Adv Wound Care (New Rochelle)· June 2015

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A small molecule PAI-1 functional inhibitor attenuates neointimal hyperplasia and vascular smooth muscle cell survival by promoting PAI-1 cleavage.
Tessa M Simone, Stephen P Higgins, Jaclyn Archambeault, Craig E Higgins, Roman G Ginnan

Cell Signal· May 2015

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The basic helix-loop-helix/leucine zipper transcription factor USF2 integrates serum-induced PAI-1 expression and keratinocyte growth.
Li Qi, Craig E Higgins, Stephen P Higgins, Brian K Law, Tessa M Simone

J Cell Biochem· October 2014

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Chemical Antagonists of Plasminogen Activator Inhibitor-1: Mechanisms of Action and Therapeutic Potential in Vascular Disease.
Tessa M Simone, Stephen P Higgins, Craig E Higgins, Michelle R Lennartz, Paul J Higgins

J Mol Genet Med· October 2014

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Small Molecule PAI-1 Functional Inhibitor Attenuates Vascular Smooth Muscle Cell Migration and Survival: Implications for the Therapy of Vascular Disease.
Tessa M Simone, Paul J Higgins

New Horiz Transl Med· September 2014

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SERPINE1: A Molecular Switch in the Proliferation-Migration Dichotomy in Wound-"Activated" Keratinocytes.
Tessa M Simone, Craig E Higgins, Ralf-Peter Czekay, Brian K Law, Stephen P Higgins

Adv Wound Care (New Rochelle)· March 2014

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Small Molecule Targeting of PAI-1 Function: A New Therapeutic Approach for Treatment of Vascular Stenosis.
Tessa M Simone, Jaclyn Archambeault, Paul J Higgins

J Mol Genet Med· July 2013

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Low Molecular Weight Antagonists of Plasminogen Activator Inhibitor-1: Therapeutic Potential in Cardiovascular Disease.
Tessa M Simone, Paul J Higgins

Mol Med Ther· August 2012

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Disease-modifying agents in the treatment of multiple sclerosis: a review of long-term outcomes.
Oleksandra Katrych, Tessa M Simone, Shara Azad, Shaker A Mousa

CNS Neurol Disord Drug Targets· December 2009

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Nanoparticles and cancer therapy: a concise review with emphasis on dendrimers.
Dhruba J Bharali, Marianne Khalil, Mujgan Gurbuz, Tessa M Simone, Shaker A Mousa

Int J Nanomedicine· July 2009

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The impact of direct-to-consumer advertised drugs on drug sales in the US and New Zealand.
Edward Norey, Tessa M Simone, Shaker A Mousa

Appl Health Econ Health Policy· May 2009

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Dual targeting of the antagonistic pathways mediated by Sirt1 and TXNIP as a putative approach to enhance the efficacy of anti-aging interventions.
Shaker A Mousa, Christine Gallati, Tessa Simone, Emmy Dier, Murat Yalcin

Aging (Albany NY)· March 2009

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Resveratrol causes COX-2- and p53-dependent apoptosis in head and neck squamous cell cancer cells.
Hung-Yun Lin, Mingzeng Sun, Heng-Yuan Tang, Tessa M Simone, Yun-Hsuan Wu

J Cell Biochem· August 2008

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NADPH analog binding to constitutive nitric oxide activates electron transfer and NO synthesis.
Rachel J Jones, Ying Tong Gao, Tessa M Simone, John C Salerno, Susan M E Smith

Nitric Oxide· May 2006

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