Publications by authors named "Thao N D Pham"

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BET Inhibition Rescues Acinar-Ductal-Metaplasia and Ciliogenesis and Ameliorates Chronic Pancreatitis-Driven Changes in Mice With Loss of the Polarity Protein Par3.
Mario A Shields, Anastasia E Metropulos, Christina Spaulding, Khulood A Alzahrani, Tomonori Hirose, Thao N D Pham

Cell Mol Gastroenterol Hepatol· October 2024

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BET inhibition rescues ciliogenesis and ameliorates pancreatitis-driven phenotypic changes in mice with Par3 loss.
Mario A Shields, Anastasia E Metropulos, Christina Spaulding, Tomonori Hirose, Shigeo Ohno, Thao N D Pham

bioRxiv· September 2023

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Calcium channel blockers potentiate gemcitabine chemotherapy  in pancreatic cancer.
Daniel R Principe, Alexandre F Aissa, Sandeep Kumar, Thao N D Pham, Patrick W Underwood

Proc Natl Acad Sci U S A· May 2022

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Gα13 loss in Kras/Tp53 mouse model of pancreatic tumorigenesis promotes tumors susceptible to rapamycin.
Mario A Shields, Christina Spaulding, Anastasia E Metropulos, Mahmoud G Khalafalla, Thao N D Pham

Cell Rep· March 2022

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XP-524 is a dual-BET/EP300 inhibitor that represses oncogenic KRAS and potentiates immune checkpoint inhibition in pancreatic cancer.
Daniel R Principe, Rui Xiong, Yangfeng Li, Thao N D Pham, Suneel D Kamath

Proc Natl Acad Sci U S A· January 2022

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Rational Design, Optimization, and Biological Evaluation of Novel MEK4 Inhibitors against Pancreatic Adenocarcinoma.
Ada J Kwong, Thao N D Pham, Hannah E Oelschlager, Hidayatullah G Munshi, Karl A Scheidt

ACS Med Chem Lett· October 2021

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Preclinical Models of Pancreatic Ductal Adenocarcinoma and Their Utility in Immunotherapy Studies.
Thao N D Pham, Mario A Shields, Christina Spaulding, Daniel R Principe, Bo Li

Cancers (Basel)· January 2021

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Controlling TIME: How MNK Kinases Function to Shape Tumor Immunity.
Thao N D Pham, Christina Spaulding, Hidayatullah G Munshi

Cancers (Basel)· July 2020

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Quercetin Enhances the Anti-Tumor Effects of BET Inhibitors by Suppressing hnRNPA1.
Thao N D Pham, Sophie Stempel, Mario A Shields, Christina Spaulding, Krishan Kumar

Int J Mol Sci· September 2019

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Induction of MNK Kinase-dependent eIF4E Phosphorylation by Inhibitors Targeting BET Proteins Limits Efficacy of BET Inhibitors.
Thao N D Pham, Krishan Kumar, Brian T DeCant, Meng Shang, Samad Z Munshi

Mol Cancer Ther· February 2019

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Protein kinase C α enhances migration of breast cancer cells through FOXC2-mediated repression of p120-catenin.
Thao N D Pham, Bethany E Perez White, Huiping Zhao, Fariborz Mortazavi, Debra A Tonetti

BMC Cancer· December 2017

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Selective Human Estrogen Receptor Partial Agonists (ShERPAs) for Tamoxifen-Resistant Breast Cancer.
Rui Xiong, Hitisha K Patel, Lauren M Gutgesell, Jiong Zhao, Loruhama Delgado-Rivera, Thao N D Pham

J Med Chem· January 2016

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PTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors.
Maoyu Peng, Rajyasree Emmadi, Zebin Wang, Elizabeth L Wiley, Peter H Gann, Thao N D Pham

Oncotarget· August 2014

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Multisite light-induced phosphorylation of the transcription factor PIF3 is necessary for both its rapid degradation and concomitant negative feedback modulation of photoreceptor phyB levels in Arabidopsis.
Weimin Ni, Shou-Ling Xu, Robert J Chalkley, Thao Nguyen D Pham, Shenheng Guan

Plant Cell· July 2013

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