Publications by authors named "Thomas C Becker"

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Pathogenesis of Barrett's Esophagus: Evolving and Emerging Mechanisms.
Omar Martinez-Uribe, Thomas C Becker, Katherine S Garman

Gastrointest Endosc Clin N Am· January 2026

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Promises and Limitations of Current Models for Understanding Barrett's Esophagus and Esophageal Adenocarcinoma.
Omar Martinez-Uribe, Thomas C Becker, Katherine S Garman

Cell Mol Gastroenterol Hepatol· May 2024

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APOL1-mediated monovalent cation transport contributes to APOL1-mediated podocytopathy in kidney disease.
Somenath Datta, Brett M Antonio, Nathan H Zahler, Jonathan W Theile, Doug Krafte, Thomas C Becker

J Clin Invest· January 2024

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HOPX injury-resistant intestinal stem cells drive epithelial recovery after severe intestinal ischemia.
Amy Stieler Stewart, Cecilia Renee Schaaf, Jennifer A Luff, John M Freund, Thomas C Becker

Am J Physiol Gastrointest Liver Physiol· November 2021

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Reductive TCA cycle metabolism fuels glutamine- and glucose-stimulated insulin secretion.
Guo-Fang Zhang, Mette V Jensen, Sarah M Gray, Kimberley El, You Wang, Thomas C Becker

Cell Metab· April 2021

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Hepatic hexokinase domain containing 1 (HKDC1) improves whole body glucose tolerance and insulin sensitivity in pregnant mice.
Md Wasim Khan, Medha Priyadarshini, Jose Cordoba-Chacon, Thomas C Becker, Brian T Layden

Biochim Biophys Acta Mol Basis Dis· March 2019

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Hepatic HKDC1 Expression Contributes to Liver Metabolism.
Carolina M Pusec, Adam De Jesus, Md Wasim Khan, Alexander R Terry, Anton E Ludvik, Thomas C Becker

Endocrinology· February 2019

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Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing.
Jonathan M Haldeman, Amanda E Conway, Michelle E Arlotto, Dorothy H Slentz, Deborah M Muoio, Thomas C Becker

Nucleic Acids Res· February 2019

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Syntaxin 4 Expression in Pancreatic β-Cells Promotes Islet Function and Protects Functional β-Cell Mass.
Eunjin Oh, Miwon Ahn, Solomon Afelik, Thomas C Becker, Bart O Roep

Diabetes· December 2018

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Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas.
Huan Wang, Aaron Bender, Peng Wang, Esra Karakose, William B Inabnet, Thomas C Becker

Nat Commun· October 2017

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A Pdx-1-Regulated Soluble Factor Activates Rat and Human Islet Cell Proliferation.
Heather L Hayes, Lu Zhang, Thomas C Becker, Jonathan M Haldeman, Samuel B Stephens

Mol Cell Biol· December 2016

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The Brain-to-Pancreatic Islet Neuronal Map Reveals Differential Glucose Regulation From Distinct Hypothalamic Regions.
Wilfredo Rosario, Inderroop Singh, Arnaud Wautlet, Christa Patterson, Jonathan Flak, Thomas C Becker

Diabetes· September 2016

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Aurora Kinase A is critical for the Nkx6.1 mediated β-cell proliferation pathway.
Amanda Hobson, Carrie Draney, Andrew Stratford, Thomas C Becker, Danhong Lu

Islets· May 2016

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Erratum. Small Interfering RNA-Mediated Suppression of Proislet Amyloid Polypeptide Expression Inhibits Islet Amyloid Formation and Enhances Survival of Human Islets in Culture. Diabetes 2008;57:3045-3055.
Lucy Marzban, Alejandra Tomas, Thomas C Becker, Lawrence Rosenberg, Jose Oberholzer

Diabetes· March 2016

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Coordinated regulatory variation associated with gestational hyperglycaemia regulates expression of the novel hexokinase HKDC1.
Cong Guo, Anton E Ludvik, Michelle E Arlotto, M Geoffrey Hayes, Loren L Armstrong, Thomas C Becker

Nat Commun· February 2015

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The mitochondrial 2-oxoglutarate carrier is part of a metabolic pathway that mediates glucose- and glutamine-stimulated insulin secretion.
Matthew L Odegaard, Jamie W Joseph, Mette V Jensen, Danhong Lu, Olga Ilkayeva, Thomas C Becker

J Biol Chem· May 2010

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Regulation of skeletal muscle oxidative capacity and insulin signaling by the mitochondrial rhomboid protease PARL.
Anthony E Civitarese, Paul S MacLean, Stacy Carling, Lyndal Kerr-Bayles, Ryan P McMillan, Thomas C Becker

Cell Metab· May 2010

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Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3.
Keith R Anderson, Ciara A Torres, Keely Solomon, Thomas C Becker, Christopher B Newgard

J Biol Chem· November 2009

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Relationship among brain and blood glucose levels and spontaneous and glucoprivic feeding.
Ambrose A Dunn-Meynell, Nicole M Sanders, Douglas Compton, Thomas C Becker, Jun-ichi Eiki

J Neurosci· May 2009

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Small interfering RNA-mediated suppression of proislet amyloid polypeptide expression inhibits islet amyloid formation and enhances survival of human islets in culture.
Lucy Marzban, Alejandra Tomas, Thomas C Becker, Lawrence Rosenberg, Jose Oberholzer

Diabetes· November 2008

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Ventromedial hypothalamic glucokinase is an important mediator of the counterregulatory response to insulin-induced hypoglycemia.
Barry E Levin, Thomas C Becker, Jun-ichi Eiki, Bei B Zhang, Ambrose A Dunn-Meynell

Diabetes· May 2008

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Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1.
Jonathan C Schisler, Patrick T Fueger, Daniella A Babu, Hans E Hohmeier, Jeffery S Tessem, Thomas C Becker

Mol Cell Biol· May 2008

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Chronic suppression of acetyl-CoA carboxylase 1 in beta-cells impairs insulin secretion via inhibition of glucose rather than lipid metabolism.
Sarah M Ronnebaum, Jamie W Joseph, Olga Ilkayeva, Shawn C Burgess, Danhong Lu, Thomas C Becker

J Biol Chem· May 2008

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CCAAT/enhancer-binding protein beta deletion reduces adiposity, hepatic steatosis, and diabetes in Lepr(db/db) mice.
Jill M Schroeder-Gloeckler, Shaikh Mizanoor Rahman, Rachel C Janssen, Liping Qiao, Jianhua Shao, Thomas C Becker

J Biol Chem· May 2007

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Functional genomics of the beta-cell: short-chain 3-hydroxyacyl-coenzyme A dehydrogenase regulates insulin secretion independent of K+ currents.
Olga T Hardy, Hans E Hohmeier, Thomas C Becker, Elisabetta Manduchi, Nicolai M Doliba

Mol Endocrinol· March 2007

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