Publications by authors named "Thomas D Nightingale"

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TRIB3 Links Endoplasmic Reticulum Stress to Impaired Efferocytosis in Atherosclerosis.
Aarushi Singhal, Stefan Russo, Umesh Kumar Dhawan, Kunzangla Bhutia, Christopher G Bell, Thomas D Nightingale

Circ Res· December 2025

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Probing rare von Willebrand disease-causing mutations in the D4 and C-domains of von Willebrand factor.
Golzar Mobayen, Sammy El-Mansi, Alain Chion, Thomas D Nightingale, Thomas A J McKinnon

Res Pract Thromb Haemost· May 2025

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Myosin-1C augments endothelial secretion of von Willebrand factor by linking contractile actomyosin machinery to the plasma membrane.
Sammy El-Mansi, Tom P Mitchell, Golzar Mobayen, Thomas A J McKinnon, Pika Miklavc, Thomas D Nightingale

Blood Adv· September 2024

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Senescent endothelial cells promote pathogenic neutrophil trafficking in inflamed tissues.
Loïc Rolas, Monja Stein, Anna Barkaway, Natalia Reglero-Real, Elisabetta Sciacca, Thomas D Nightingale

EMBO Rep· September 2024

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Neuropilin-1 interacts with VE-cadherin and TGFBR2 to stabilize adherens junctions and prevent activation of endothelium under flow.
Emy Bosseboeuf, Anissa Chikh, Ahmed Bey Chaker, Tom P Mitchell, Dhilakshani Vignaraja, Thomas D Nightingale

Sci Signal· May 2023

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Proximity proteomics identifies septins and PAK2 as decisive regulators of actomyosin-mediated expulsion of von Willebrand factor.
Sammy El-Mansi, Christopher L Robinson, Katja B Kostelnik, Jessica J McCormack, Tom P Mitchell, Thomas D Nightingale

Blood· February 2023

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Genome wide CRISPR/Cas9 screen identifies the coagulation factor IX (F9) as a regulator of senescence.
Paula Carpintero-Fernández, Michela Borghesan, Olga Eleftheriadou, Belen Pan-Castillo, Juan Antonio Fafián-Labora, Thomas D Nightingale

Cell Death Dis· February 2022

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Autophagy modulates endothelial junctions to restrain neutrophil diapedesis during inflammation.
Natalia Reglero-Real, Lorena Pérez-Gutiérrez, Azumi Yoshimura, Loïc Rolas, José Garrido-Mesa, Thomas D Nightingale

Immunity· September 2021

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Emerging mechanisms to modulate VWF release from endothelial cells.
Sammy El-Mansi, Thomas D Nightingale

Int J Biochem Cell Biol· February 2021

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Dynamic trafficking and turnover of JAM-C is essential for endothelial cell migration.
Katja B Kostelnik, Amy Barker, Christopher Schultz, Tom P Mitchell, Vinothini Rajeeve, Thomas D Nightingale

PLoS Biol· December 2019

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Clathrin-mediated post-fusion membrane retrieval influences the exocytic mode of endothelial Weibel-Palade bodies.
Nicola L Stevenson, Ian J White, Jessica J McCormack, Christopher Robinson, Daniel F Cutler, Thomas D Nightingale

J Cell Sci· August 2017

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Actin coats and rings promote regulated exocytosis.
Thomas D Nightingale, Daniel F Cutler, Louise P Cramer

Trends Cell Biol· June 2012

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Myosin Va acts in concert with Rab27a and MyRIP to regulate acute von-Willebrand factor release from endothelial cells.
Inés Rojo Pulido, Thomas D Nightingale, François Darchen, Miguel C Seabra, Daniel F Cutler

Traffic· October 2011

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Actomyosin II contractility expels von Willebrand factor from Weibel-Palade bodies during exocytosis.
Thomas D Nightingale, Ian J White, Emily L Doyle, Mark Turmaine, Kimberly J Harrison-Lavoie

J Cell Biol· August 2011

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Rab27a and MyRIP regulate the amount and multimeric state of VWF released from endothelial cells.
Thomas D Nightingale, Krupa Pattni, Alistair N Hume, Miguel C Seabra, Daniel F Cutler

Blood· May 2009

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A mechanism of sialylation functionally silences the hyaluronan receptor LYVE-1 in lymphatic endothelium.
Thomas D Nightingale, Matthew E F Frayne, Steven Clasper, Suneale Banerji, David G Jackson

J Biol Chem· February 2009

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Aftiphilin and gamma-synergin are required for secretagogue sensitivity of Weibel-Palade bodies in endothelial cells.
Winnie W Y Lui-Roberts, Francesco Ferraro, Thomas D Nightingale, Daniel F Cutler

Mol Biol Cell· December 2008

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Formation and function of Weibel-Palade bodies.
Daniel J Metcalf, Thomas D Nightingale, Helen L Zenner, Winnie W Lui-Roberts, Daniel F Cutler

J Cell Sci· January 2008

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