Publications by authors named "Thomas Geiger"

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A Facile Protocol for C(sp)-C(sp) Bond Formation Reactions Toward Functionalized E3 Ligase Ligands.
Anita Maksutova, Thomas M Geiger, Lorenzo Cianni, Dominika E Pieńkowska, Jan Gerhartz

ChemMedChem· December 2025

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How state firework restrictions affect the incidence of paediatric firework injuries in the USA.
Nicholas Tranchitella, Emily Wilson, Thomas Geiger, William Barfield, Ian Kane

Inj Prev· September 2025

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Enhancing Solubility in VHL-Based PROTACs: Optimized USP7 Degraders for Improved Developability.
Sophie Wittenburg, Maximilian R Zuleeg, Kirsten Peter, Patricia Lemnitzer, Rabea Voget, Thomas M Geiger

J Med Chem· August 2025

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The SPHN Schema Forge - transform healthcare semantics from human-readable to machine-readable by leveraging semantic web technologies.
Vasundra Touré, Deepak Unni, Philip Krauss, Abdelhamid Abdelwahed, Jascha Buchhorn, Thomas R Geiger

J Biomed Semantics· May 2025

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Conformationally Restricted Macrocycles as Improved FKBP51 Inhibitors Enabled by Systematic Linker Derivatization.
Moritz Spiske, Christian Meyners, Michael Bauder, Maximilian Repity, Christian Brudy, Thomas M Geiger

Angew Chem Int Ed Engl· March 2025

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Discovery of fully synthetic FKBP12-mTOR molecular glues.
Robin C E Deutscher, Christian Meyners, Maximilian L Repity, Wisely Oki Sugiarto, Jürgen M Kolos, Thomas M Geiger

Chem Sci· March 2025

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Printed circuit board substrates derived from lignocellulose nanofibrils for sustainable electronics applications.
Yuliia Dudnyk, Pavel Kulha, Václav Procházka, Gustav Nyström, Thomas Geiger

Sci Rep· March 2025

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Light-activatable photochemically targeting chimeras (PHOTACs) enable the optical control of targeted protein degradation of HDAC6.
Silas L Wurnig, Maria Hanl, Thomas M Geiger, Shiyang Zhai, Ina Dressel

RSC Med Chem· March 2025

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An engineered cereblon optimized for high-throughput screening and molecular glue discovery.
Henry J Bailey, Jonathan Eisert, Rubina Kazi, Jan Gerhartz, Dominika Ewa Pieńkowska, Thomas M Geiger

Cell Chem Biol· February 2025

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Structural and biochemical insights into FKBP51 as a Hsp90 co-chaperone.
Asat Baischew, Sarah Engel, Thomas M Geiger, Martha C Taubert, Felix Hausch

J Cell Biochem· December 2024

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Use of Poly(vinyl alcohol) in Spray-Dried Dispersions: Enhancing Solubility and Stability of Proteolysis Targeting Chimeras.
Lena Mareczek, Lena K Mueller, Laura Halstenberg, Thomas M Geiger, Michael Walz

Pharmaceutics· July 2024

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Identifying PFAS hotspots in surface waters of South Carolina using a new optimized total organic fluorine method and target LC-MS/MS.
Alexandria L B Forster, Thomas C Geiger, Gina O Pansari, Patrick T Justen, Susan D Richardson

Water Res· June 2024

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SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration.
Jakob Hartmann, Thomas Bajaj, Joy Otten, Claudia Klengel, Tim Ebert, Thomas M Geiger

Nat Commun· March 2024

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Predicting Medical Student Performance With a Situational Judgment Test in Admissions.
Marlene P Ballejos, Christina Cestone, H Liesel Copeland, Dana M Dunleavy, Thomas Geiger

Acad Med· February 2024

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Discovery of a Potent Proteolysis Targeting Chimera Enables Targeting the Scaffolding Functions of FK506-Binding Protein 51 (FKBP51).
Thomas M Geiger, Michael Walz, Christian Meyners, Angela Kuehn, Johannes K Dreizler

Angew Chem Int Ed Engl· January 2024

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What are the bottlenecks to health data sharing in Switzerland? An interview study.
Kelly E Ormond, Sabine Bavamian, Claudia Becherer, Christine Currat, Francisca Joerger, Thomas R Geiger

Swiss Med Wkly· January 2024

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Large-scale, in-cell photocrosslinking at single-residue resolution reveals the molecular basis for glucocorticoid receptor regulation by immunophilins.
Asat Baischew, Sarah Engel, Martha C Taubert, Thomas M Geiger, Felix Hausch

Nat Struct Mol Biol· December 2023

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[4.3.1]Bicyclic FKBP Ligands Inhibit Legionella Pneumophila Infection by LpMip-Dependent and LpMip-Independent Mechanisms.
Robin C E Deutscher, M Safa Karagöz, Patrick L Purder, Jürgen M Kolos, Christian Meyners, Thomas M Geiger

Chembiochem· November 2023

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Structure-Based Discovery of a New Selectivity-Enabling Motif for the FK506-Binding Protein 51.
Fabian H Knaup, Christian Meyners, Wisely Oki Sugiarto, Saskia Wedel, Margherita Springer, Thomas M Geiger

J Med Chem· April 2023

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Chemical Doping by Fluorination and Its Impact on All Energy Levels of π-Conjugated Systems.
Daniel Bischof, Yurii Radiev, Matthias W Tripp, Philipp E Hofmann, Thomas Geiger

J Phys Chem Lett· March 2023

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Hierarchical Structure of Cellulose Nanofibril-Based Foams Explored by Multimodal X-ray Scattering.
Viviane Lutz-Bueno, Ana Diaz, Tingting Wu, Gustav Nyström, Thomas Geiger

Biomacromolecules· March 2022

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Picomolar FKBP inhibitors enabled by a single water-displacing methyl group in bicyclic [4.3.1] aza-amides.
Jürgen M Kolos, Sebastian Pomplun, Sascha Jung, Benedikt Rieß, Patrick L Purder, Thomas M Geiger

Chem Sci· November 2021

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Permanent Dipole Moments Enhance Electronic Coupling and Singlet Fission in Pentacene.
Clemens Zeiser, Luca Moretti, Thomas Geiger, Lukas Kalix, Ana M Valencia

J Phys Chem Lett· August 2021

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Development of NanoBRET-Binding Assays for FKBP-Ligand Profiling in Living Cells.
Monika T Gnatzy, Thomas M Geiger, Angela Kuehn, Niklas Gutfreund, Michael Walz

Chembiochem· July 2021

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Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion.
Silvia Martinelli, Elmira A Anderzhanova, Thomas Bajaj, Svenja Wiechmann, Frederik Dethloff, Thomas M Geiger

Nat Commun· July 2021

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