Publications by authors named "Thomas L Hunt"

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Results of two Phase 1, Randomized, Double-blind, Placebo-controlled, Studies (Ascending Single-dose and Multiple-dose Studies) to Determine the Safety, Tolerability, and Pharmacokinetics of Orally Administered LX9211 in Healthy Participants.
LuAnn Bundrant, Thomas L Hunt, Phil Banks, Suma Gopinathan, Kristi A Boehm

Clin Ther· June 2021

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The Effect of Verapamil, a P-gp Inhibitor, on the Pharmacokinetics, Safety, and Tolerability of Omadacycline in Healthy Adults: A Phase I, Open-Label, Single-Sequence Study.
Thomas L Hunt, Evan Tzanis, Stephen Bai, Amy Manley, Surya Chitra

Eur J Drug Metab Pharmacokinet· January 2021

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Evaluation of Eluxadoline Effect on Cardiac Repolarization.
Laura Bonifacio, Thomas L Hunt, Gail McIntyre, Leonard S Dove, Paul S Covington

Clin Pharmacol Drug Dev· September 2018

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Safety, tolerability and pharmacokinetics of AFN-1252 administered as immediate release tablets in healthy subjects.
Barry Hafkin, Nachum Kaplan, Thomas L Hunt

Future Microbiol· September 2016

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Integration of modeling and simulation to support changes to ondansetron dosing following a randomized, double-blind, placebo-, and active-controlled thorough QT study.
Peiying Zuo, Lynda J Haberer, Lei Fang, Thomas L Hunt, Derry Ridgway

J Clin Pharmacol· November 2014

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Effect of the thrombin receptor antagonist (PAR-1) vorapaxar on QT/QTc interval in healthy volunteers: A randomized, placebo- and positive-controlled, parallel group trial.
Teddy Kosoglou, Thomas L Hunt, Fengjuan Xuan, Bharath Kumar, Paul Statkevich

Clin Pharmacol Drug Dev· January 2014

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Effect of pitavastatin vs. rosuvastatin on international normalized ratio in healthy volunteers on steady-state warfarin.
Christine Y Yu, Stuart E Campbell, Baojin Zhu, Mary Pat Knadler, David S Small, Thomas L Hunt

Curr Med Res Opin· February 2012

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The ability of atropine to prevent and reverse the negative chronotropic effect of fingolimod in healthy subjects.
John M Kovarik, Alan Slade, Gilles-Jacques Riviere, Daniel Neddermann, Steve Maton, Thomas L Hunt

Br J Clin Pharmacol· August 2008

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A mechanistic study to assess whether isoproterenol can reverse the negative chronotropic effect of fingolimod.
John M Kovarik, Gilles-Jacques Riviere, Daniel Neddermann, Steve Maton, Thomas L Hunt

J Clin Pharmacol· March 2008

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The effect of etoricoxib on the pharmacodynamics and pharmacokinetics of warfarin.
Jules I Schwartz, Nancy G B Agrawal, Alan H Hartford, Josee Cote, Thomas L Hunt

J Clin Pharmacol· May 2007

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FTY720: placebo-controlled study of the effect on cardiac rate and rhythm in healthy subjects.
Robert Schmouder, Denise Serra, Yibin Wang, John M Kovarik, John DiMarco, Thomas L Hunt

J Clin Pharmacol· August 2006

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Evaluation of safety and pharmacokinetics of consecutive multiple-day dosing of palonosetron in healthy subjects.
Thomas L Hunt, Susan C Gallagher, Michael T Cullen, Ajit K Shah

J Clin Pharmacol· May 2005

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Pharmacokinetics of palonosetron in combination with aprepitant in healthy volunteers.
Ajit K Shah, Thomas L Hunt, Susan C Gallagher, Michael T Cullen

Curr Med Res Opin· April 2005

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Pharmacokinetics of treprostinil sodium administered by 28-day chronic continuous subcutaneous infusion.
Michael Wade, F Jo Baker, Robert Roscigno, Wayne DellaMaestra, Carl P Arneson, Thomas L Hunt

J Clin Pharmacol· May 2004

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Absolute bioavailability and pharmacokinetics of treprostinil sodium administered by acute subcutaneous infusion.
Michael Wade, F Jo Baker, Robert Roscigno, Wayne DellaMaestra, Thomas L Hunt

J Clin Pharmacol· January 2004

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Effect of continuous subcutaneous treprostinil therapy on the pharmacodynamics and pharmacokinetics of warfarin.
Michael Wade, Thomas L Hunt, Allen A Lai

J Cardiovasc Pharmacol· June 2003

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Effects of three fluoroquinolones on QT interval in healthy adults after single doses.
Gary J Noel, Jaya Natarajan, Shuchean Chien, Thomas L Hunt, Daniel B Goodman

Clin Pharmacol Ther· April 2003

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Single- and multiple-dose pharmacokinetics of etoricoxib, a selective inhibitor of cyclooxygenase-2, in man.
Nancy G B Agrawal, Arturo G Porras, Catherine Z Matthews, Mark J Rose, Eric J Woolf, Thomas L Hunt

J Clin Pharmacol· March 2003

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Single- and multiple-dose pharmacokinetics of caspofungin in healthy men.
Julie A Stone, Sherry D Holland, Peter J Wickersham, Andrew Sterrett, Michael Schwartz, Thomas L Hunt

Antimicrob Agents Chemother· March 2002

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