Publications by authors named "Thomas Moss"

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A conserved Hsp70 phosphorylation regulates cell cycle progression after DNA damage.
Thomas Moss, Alexandra Wooldredge, Koustav Bhakta, Matthew Cronin, Jason E Gestwicki

bioRxiv· September 2025

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Hsc70-4: An unanticipated mediator of dsRNA internalization in .
Sabrina J Fletcher, Eugenia S Bardossy, Lorena Tomé-Poderti, Thomas Moss, Vanesa Mongelli

Sci Adv· May 2025

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Intermolecular Asymmetric Arylative Dearomatization of 1-Naphthols.
Max Kadarauch, Thomas A Moss, Robert J Phipps

J Am Chem Soc· December 2024

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The Next-Generation Oral Selective Estrogen Receptor Degrader Camizestrant (AZD9833) Suppresses ER+ Breast Cancer Growth and Overcomes Endocrine and CDK4/6 Inhibitor Resistance.
Mandy Lawson, Natalie Cureton, Susana Ros, Azadeh Cheraghchi-Bashi, Jelena Urosevic, Jennifer Moss, Thomas A Moss

Cancer Res· December 2023

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Case Report: Limbic encephalitis following treatment with durvalumab for small-cell lung cancer.
Thomas T Moss, Knut Stavem, Astrid Aandahl, Anne S Gløersen, Bjørn H Grønberg

Front Immunol· November 2023

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Discovery and Optimization of the First ATP Competitive Type-III c-MET Inhibitor.
Iacovos N Michaelides, Gavin W Collie, Ulf Börjesson, Christina Vasalou, Omar Alkhatib, Thomas A Moss

J Med Chem· July 2023

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Discovery of a Potent and Orally Bioavailable Zwitterionic Series of Selective Estrogen Receptor Degrader-Antagonists.
James S Scott, Darren Stead, Bernard Barlaam, Jason Breed, Rodrigo J Carbajo, Thomas A Moss

J Med Chem· February 2023

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Actual and projected gaps in the provision of residential aged care in New South Wales, Australia.
Adam Austin, Thomas-Hoang Le, Thomas Moss, Stuart Wark

Aust Health Rev· August 2022

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Discovery of a Potent and Selective ATAD2 Bromodomain Inhibitor with Antiproliferative Activity in Breast Cancer Models.
Jon J Winter-Holt, Catherine Bardelle, Elisabetta Chiarparin, Ian L Dale, Paul R J Davey, Thomas A Moss

J Med Chem· February 2022

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Discovery of AZD9833, a Potent and Orally Bioavailable Selective Estrogen Receptor Degrader and Antagonist.
James S Scott, Thomas A Moss, Amber Balazs, Bernard Barlaam, Jason Breed

J Med Chem· December 2020

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Addition of Fluorine and a Late-Stage Functionalization (LSF) of the Oral SERD AZD9833.
James S Scott, Thomas A Moss, Bernard Barlaam, Paul R J Davey, Gary Fairley

ACS Med Chem Lett· December 2020

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An efficient, stereocontrolled and versatile synthetic route to bicyclic partially saturated privileged scaffolds.
Hannah L Stewart, Abigail R Hanby, Thomas A King, Andrew D Bond, Thomas A Moss

Chem Commun (Camb)· June 2020

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Surgical decompression of arachnoid cysts leads to improved quality of life: a prospective study-long-term follow-up.
Thomas Moss, Christian A Helland, Svein H Mørkve, Knut Wester

Acta Neurochir (Wien)· November 2019

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Building Bridges in a Series of Estrogen Receptor Degraders: An Application of Metathesis in Medicinal Chemistry.
James S Scott, Jason Breed, Rodrigo J Carbajo, Paul R Davey, Ryan Greenwood, Thomas A Moss

ACS Med Chem Lett· October 2019

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Tricyclic Indazoles-A Novel Class of Selective Estrogen Receptor Degrader Antagonists.
James S Scott, Andrew Bailey, David Buttar, Rodrigo J Carbajo, Jon Curwen, Thomas A Moss

J Med Chem· February 2019

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Platelet-Derived Mitochondria Display Embryonic Stem Cell Markers and Improve Pancreatic Islet β-cell Function in Humans.
Yong Zhao, Zhaoshun Jiang, Elias Delgado, Heng Li, Huimin Zhou, Thomas Moss

Stem Cells Transl Med· August 2017

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PreSERVE-AMI: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Intracoronary Administration of Autologous CD34+ Cells in Patients With Left Ventricular Dysfunction Post STEMI.
Arshed A Quyyumi, Alejandro Vasquez, Dean J Kereiakes, Marc Klapholz, Gary L Schaer, Thomas Moss

Circ Res· January 2017

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AZD9496: An Oral Estrogen Receptor Inhibitor That Blocks the Growth of ER-Positive and ESR1-Mutant Breast Tumors in Preclinical Models.
Hazel M Weir, Robert H Bradbury, Mandy Lawson, Alfred A Rabow, David Buttar, Thomas Moss

Cancer Res· June 2016

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Tetrahydroisoquinoline Phenols: Selective Estrogen Receptor Downregulator Antagonists with Oral Bioavailability in Rat.
James S Scott, Andrew Bailey, Robert D M Davies, Sébastien L Degorce, Philip A MacFaul, Thomas Moss

ACS Med Chem Lett· January 2016

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Reference Ranges for Head Circumference in Ethiopian Children 0-2 Years of Age.
Ephrem Bililigne Amare, Mari Idsøe, Miriam Wiksnes, Thomas Moss, Mathieu Roelants

World Neurosurg· December 2015

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Modulation of Autoimmune T-Cell Memory by Stem Cell Educator Therapy: Phase 1/2 Clinical Trial.
Elias Delgado, Marcos Perez-Basterrechea, Beatriz Suarez-Alvarez, Huimin Zhou, Eva Martinez Revuelta, Thomas Moss

EBioMedicine· December 2015

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Optimization of a Novel Binding Motif to (E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic Acid (AZD9496), a Potent and Orally Bioavailable Selective Estrogen Receptor Downregulator and Antagonist.
Chris De Savi, Robert H Bradbury, Alfred A Rabow, Richard A Norman, Camila de Almeida, Thomas A Moss

J Med Chem· October 2015

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Meeting report for Odd Pols 2012.
Astrid M Roy-Engel, Thomas Moss, Richard J Maraia

Gene· August 2013

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Catalytic asymmetric alkylation reactions for the construction of protected ethylene-amino and propylene-amino motifs attached to quaternary stereocentres.
Thomas A Moss, David M Barber, Andrew F Kyle, Darren J Dixon

Chemistry· February 2013

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Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum.
Nicholas A Malmquist, Thomas A Moss, Salah Mecheri, Artur Scherf, Matthew J Fuchter

Proc Natl Acad Sci U S A· October 2012

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