Publications by authors named "Tim Fryer"

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Azathioprine for the treatment of early Parkinson's disease (AZA-PD): a randomised, double-blind, placebo-controlled, proof-of-concept, phase 2 trial.
Julia C Greenland, Kerry Dresser, Emma Cutting, Rachel Donegan, Simon Bond, Tim D Fryer

Lancet Neurol· January 2026

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A novel blood-free analytical framework for the quantification of neuroinflammatory load from TSPO PET imaging.
Lucia Maccioni, Ludovica Brusaferri, Leonardo Barzon, Julia J Schubert, Maria A Nettis, Tim Fryer

J Cereb Blood Flow Metab· December 2025

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Inflammation PET and plasma neurofilament light predict survival in people with progressive supranuclear palsy.
Noah L Shapiro, Peter Simon Jones, Elijah Mak, Kamen A Tsvetanov, Julia Goddard, Tim Fryer

Brain Commun· December 2025

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Alzheimer's Imaging Consortium.
Max McLachlan, Brecca Bettcher, Andrew K McVea, Matthew D Zammit, Lisette LeMerise, Tim D Fryer

Alzheimers Dement· December 2025

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Connectivity as a universal predictor of tau progression in atypical Alzheimer's disease.
Hannah de Bruin, Colin Groot, Henryk Barthel, Gérard N Bischof, Ganna Blazhenets, Tim D Fryer

Brain· November 2025

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Constipation Is Linked to Neuroinflammation in Early Parkinson's Disease.
Marta Camacho, Julia C Greenland, Alexander R D Peattie, Lennart R B Spindler, Jonathan Holbrook, Tim D Fryer

Mov Disord· November 2025

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Comparing and combining TSPO-PET tracers in tauopathies.
Harry Crook, Nicolai Franzmeier, Nesrine Rahmouni, Johannes S Gnörich, Tim D Fryer

Eur J Nucl Med Mol Imaging· October 2025

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Network-based disease fingerprinting with neuroinflammation PET imaging.
Leonardo Barzon, Lucia Maccioni, Michelle Carranza Mellana, Julia J Schubert, Ludovica Brusaferri, Tim Fryer

Res Sq· October 2025

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Peripheral-central immune crosstalk in Parkinson's disease and its association with clinical severity.
Julia C Greenland, Jonathan Holbrook, Lakmini Kahanawita, Marta Camacho, Tim D Fryer

Brain Behav Immun· August 2025

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Post-mortem validation of in vivo TSPO PET as a microglial biomarker.
Sasvi S Wijesinghe, James B Rowe, Hannah D Mason, Kieren S J Allinson, Reuben Thomas, Tim D Fryer

Brain· June 2025

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The striatum is an early, accurate indicator of amyloid burden using [C]PiB in Down syndrome: Comparison of two radiotracers.
Max McLachlan, Brecca Bettcher, Andrew McVea, Alexandra DiFilippo, Matthew Zammit, Tim Fryer

Alzheimers Dement· April 2025

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Blood inflammation relates to neuroinflammation and survival in frontotemporal lobar degeneration.
Maura Malpetti, Peter Swann, Kamen A Tsvetanov, Leonidas Chouliaras, Alexandra Strauss, Tim D Fryer

Brain· February 2025

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Extra-axial inflammatory signal and its relationship to peripheral and central immunity in depression.
Brandi Eiff, Edward T Bullmore, Menna R Clatworthy, Tim D Fryer, Carmine M Pariante

Brain· February 2025

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Polygenic risk discriminates Lewy body dementia from Alzheimer's disease.
Anna McKeever, Peter Swann, Maura Malpetti, Paul C Donaghy, Alan Thomas, Tim D Fryer

Alzheimers Dement· February 2025

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A novel blood-free analytical framework for the quantification of neuroinflammatory load from TSPO PET Imaging.
Lucia Maccioni, Ludovica Brusaferri, Leonardo Barzon, Julia J Schubert, Maria A Nettis, Tim Fryer

Res Sq· February 2025

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The striatum is an early, accurate indicator of amyloid burden using [C]PiB in Down syndrome: comparison of two radiotracers.
Max McLachlan, Brecca Bettcher, Andrew McVea, Alexandra DiFillipo, Matthew Zammit, Tim Fryer

medRxiv· December 2024

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Outcomes and Mechanisms Associated With Selective Thalamic Neuronal Loss in Chronic Traumatic Brain Injury.
Rebecca E Woodrow, Julia Grossac, Young T Hong, Stefan Winzeck, Thomas Geeraerts, Tim D Fryer

JAMA Netw Open· August 2024

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Are central and systemic inflammation associated with fatigue in cerebral small vessel disease?
Amy A Jolly, Robin B Brown, Daniel J Tozer, Young T Hong, Tim D Fryer

Int J Stroke· July 2024

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Differential Synaptic Loss in β-Amyloid Positive Versus β-Amyloid Negative Corticobasal Syndrome.
Negin Holland, George Savulich, P Simon Jones, David J Whiteside, Duncan Street, Tim D Fryer

Mov Disord· July 2024

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MINocyclinE to Reduce inflammation and blood-brain barrier leakage in small Vessel diseAse (MINERVA): A phase II, randomized, double-blind, placebo-controlled experimental medicine trial.
Robin B Brown, Daniel J Tozer, Laurence Loubière, Eric L Harshfield, Young T Hong, Tim D Fryer

Alzheimers Dement· June 2024

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Neuroinflammation is linked to dementia risk in Parkinson's disease.
Antonina Kouli, Lennart R B Spindler, Tim D Fryer, Young T Hong, Maura Malpetti

Brain· March 2024

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Synaptic density affects clinical severity via network dysfunction in syndromes associated with frontotemporal lobar degeneration.
David J Whiteside, Negin Holland, Kamen A Tsvetanov, Elijah Mak, Maura Malpetti, Tim D Fryer

Nat Commun· December 2023

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PET/MRI of hypoxia and vascular function in ER-positive breast cancer: correlations with immunohistochemistry.
Julia C Carmona-Bozo, Roido Manavaki, Jodi L Miller, Cara Brodie, Corradina Caracò, Tim D Fryer

Eur Radiol· September 2023

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Microglial activation in the frontal cortex predicts cognitive decline in frontotemporal dementia.
Maura Malpetti, Thomas E Cope, Duncan Street, P Simon Jones, Frank H Hezemans, Tim D Fryer

Brain· August 2023

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Longitudinal Synaptic Loss in Primary Tauopathies: An In Vivo [ C]UCB-J Positron Emission Tomography Study.
Negin Holland, P Simon Jones, George Savulich, Michelle Naessens, Maura Malpetti, Tim D Fryer

Mov Disord· July 2023

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