Publications by authors named "Timothy E Benson"

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Two RNA Tunnel Inhibitors Bind in Highly Conserved Sites in Dengue Virus NS5 Polymerase: Structural and Functional Studies.
Rishi Arora, Chong Wai Liew, Tingjin Sherryl Soh, Dorcas Adobea Otoo, Cheah Chen Seh, Timothy E Benson

J Virol· November 2020

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Structure of lipoprotein lipase in complex with GPIHBP1.
Rishi Arora, Amitabh V Nimonkar, Daniel Baird, Chunhua Wang, Chun-Hao Chiu, Timothy E Benson

Proc Natl Acad Sci U S A· May 2019

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A Conserved Pocket in the Dengue Virus Polymerase Identified through Fragment-based Screening.
Christian G Noble, Siew Pheng Lim, Rishi Arora, Fumiaki Yokokawa, Shahul Nilar, Timothy E Benson

J Biol Chem· April 2016

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Identifying initiation and elongation inhibitors of dengue virus RNA polymerase in a high-throughput lead-finding campaign.
Thomas M Smith, Siew Pheng Lim, Kimberley Yue, Scott A Busby, Rishi Arora, Timothy E Benson

J Biomol Screen· January 2015

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Structural basis of substrate discrimination and integrin binding by autotaxin.
Jens Hausmann, Satwik Kamtekar, Evangelos Christodoulou, Jacqueline E Day, Tao Wu, Timothy E Benson

Nat Struct Mol Biol· February 2011

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Crystallization and preliminary X-ray diffraction analysis of rat autotaxin.
Jacqueline E Day, Troii Hall, Lyle E Pegg, Timothy E Benson, Jens Hausmann

Acta Crystallogr Sect F Struct Biol Cryst Commun· September 2010

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Structural and thermodynamic characterization of the TYK2 and JAK3 kinase domains in complex with CP-690550 and CMP-6.
Jill E Chrencik, Akshay Patny, Iris K Leung, Brian Korniski, Thomas L Emmons, Timothy E Benson

J Mol Biol· July 2010

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Crystal structure of fatty acid amide hydrolase bound to the carbamate inhibitor URB597: discovery of a deacylating water molecule and insight into enzyme inactivation.
Mauro Mileni, Satwik Kamtekar, David C Wood, Timothy E Benson, Benjamin F Cravatt

J Mol Biol· July 2010

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High resolution crystal structure of the catalytic domain of ADAMTS-5 (aggrecanase-2).
Huey-Sheng Shieh, Karl J Mathis, Jennifer M Williams, Robert L Hills, Joe F Wiese, Timothy E Benson

J Biol Chem· January 2008

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Potent and selective isophthalamide S2 hydroxyethylamine inhibitors of BACE1.
Steven W Kortum, Timothy E Benson, Michael J Bienkowski, Thomas L Emmons, D Bryan Prince

Bioorg Med Chem Lett· June 2007

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Design, synthesis, and crystal structure of hydroxyethyl secondary amine-based peptidomimetic inhibitors of human beta-secretase.
Michel C Maillard, Roy K Hom, Timothy E Benson, Joseph B Moon, Shumeye Mamo

J Med Chem· February 2007

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Design of potent inhibitors of human beta-secretase. Part 1.
John N Freskos, Yvette M Fobian, Timothy E Benson, Michael J Bienkowski, David L Brown

Bioorg Med Chem Lett· January 2007

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Design of potent inhibitors of human beta-secretase. Part 2.
John N Freskos, Yvette M Fobian, Timothy E Benson, Joseph B Moon, Michael J Bienkowski

Bioorg Med Chem Lett· January 2007

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X-ray crystal structure of Staphylococcus aureus FemA.
Timothy E Benson, D Bryan Prince, Veronica T Mutchler, Kimberly A Curry, Andrea M Ho

Structure· August 2002

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