Publications by authors named "Timothy Florin"

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Pathogenic OTUD3 Mutations Predispose to Ulcerative Colitis Due to Barrier Dysfunction.
Rabina Giri, Minyi Lee, Graham W Magor, Anne-Sophie Bergot, Yaowu He, Timothy H Florin

Cell Mol Gastroenterol Hepatol· October 2025

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Innovating Thiopurine Therapeutic Drug Monitoring: A Systematic Review and Meta-Analysis on DNA-Thioguanine Nucleotides (DNA-TG) as an Inclusive Biomarker in Thiopurine Therapy.
Ahmed B Bayoumy, A R Ansari, C J J Mulder, K Schmiegelow, Timothy Florin

Clin Pharmacokinet· August 2024

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MUC13 Cell Surface Mucin Limits Salmonella Typhimurium Infection by Protecting the Mucosal Epithelial Barrier.
Michael A McGuckin, Julie M Davies, Pascal Felgner, Kuan Yau Wong, Rabina Giri, Timothy H Florin

Cell Mol Gastroenterol Hepatol· December 2023

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Therapeutic Drug Monitoring for IBD Children on Thioguanine.
Timothy H Florin, John A Duley

J Pediatr Gastroenterol Nutr· September 2023

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Rectally Administrated Thioguanine for Distal Ulcerative Colitis: A Multicenter Case Series.
Femke Crouwel, Melek Simsek, Amarylle S van Doorn, Chris J J Mulder, Hans J C Buiter, Timothy H Florin

Inflamm Bowel Dis· June 2023

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Gut inflammation and adaptive immunity amplify acetaminophen toxicity in bowel and liver.
Saleh Y Alabbas, Rabina Giri, Iulia Oancea, Julie Davies, Veronika Schreibner, Timothy H Florin

J Gastroenterol Hepatol· April 2023

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An Extremes of Phenotype Approach Confirms Significant Genetic Heterogeneity in Patients with Ulcerative Colitis.
Sally Mortlock, Anton Lord, Grant Montgomery, Martha Zakrzewski, Lisa A Simms, Timothy H Florin

J Crohns Colitis· March 2023

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MUC1-mediated Macrophage Activation Promotes Colitis-associated Colorectal Cancer via Activating the Interleukin-6/ Signal Transducer and Activator of Transcription 3 Axis.
Yong H Sheng, Julie M Davies, Ran Wang, Kuan Yau Wong, Rabina Giri, Timothy H Florin

Cell Mol Gastroenterol Hepatol· September 2022

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Secreted NF-κB suppressive microbial metabolites modulate gut inflammation.
Rabina Giri, Emily C Hoedt, Shamsunnahar Khushi, Angela A Salim, Anne-Sophie Bergot, Timothy H Florin

Cell Rep· April 2022

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Successful Manipulation of the Gut Microbiome to Treat Spontaneous and Induced Murine Models of Colitis.
Ramya Movva, Nida Murtaza, Rabina Giri, Chin Wen Png, Julie Davies, Timothy H Florin

Gastro Hep Adv· March 2022

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A Nucleotide Analog Prevents Colitis-Associated Cancer via Beta-Catenin Independently of Inflammation and Autophagy.
Yong Hua Sheng, Rabina Giri, Julie Davies, Veronika Schreiber, Saleh Alabbas, Timothy H Florin

Cell Mol Gastroenterol Hepatol· December 2021

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Advances in Thiopurine Drug Delivery: The Current State-of-the-Art.
Ahmed B Bayoumy, Femke Crouwel, Nripen Chanda, Timothy H J Florin, Hans J C Buiter

Eur J Drug Metab Pharmacokinet· November 2021

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MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity.
Yong Hua Sheng, Kuan Yau Wong, Inge Seim, Ran Wang, Yaowu He, Timothy H Florin

Oncogene· November 2019

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Health and climate change.
Timothy H Florin, David W Allen

Lancet· June 2019

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Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease.
Gareth J Walker, James W Harrison, Graham A Heap, Michiel D Voskuil, Vibeke Andersen, Timothy H Florin

JAMA· February 2019

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A well-tolerated and rapidly acting thiopurine for IBD?
Timothy H J Florin, John D Wright, Siddharth D Jambhrunkar, Michael G Henman, Amirali Popat

Drug Discov Today· January 2019

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Entyvio lengthen dose-interval study: lengthening vedolizumab dose interval and the risk of clinical relapse in inflammatory bowel disease.
Webber Chan, Nicole Lynch, Peter Bampton, Jeff Chang, Alvin Chung, Timothy Florin

Eur J Gastroenterol Hepatol· July 2018

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Anti-TNF Therapeutic Drug Monitoring in Postoperative Crohn's Disease.
Emily K Wright, Michael A Kamm, Peter De Cruz, Amy L Hamilton, Fabiyola Selvaraj, Timothy H Florin

J Crohns Colitis· May 2018

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The role of IL-22 in the resolution of sterile and nonsterile inflammation.
Saleh Y Alabbas, Jakob Begun, Timothy H Florin, Iulia Oancea

Clin Transl Immunology· April 2018

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Colonic thioguanine pro-drug: Investigation of microbiome and novel host metabolism.
Timothy Florin, Ramya Movva, Jakob Begun, John Duley, Iulia Oancea

Gut Microbes· March 2018

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Critical assessment of thioguanine treatment for inflammatory bowel diseases: Is it time to rehabilitate this treatment?
Ramya Movva, Alison Haywood, Sohil A Khan, Timothy Hj Florin, Iulia Oancea

J Dig Dis· September 2017

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Serologic antibodies in relation to outcome in postoperative Crohn's disease.
Amy L Hamilton, Michael A Kamm, Peter De Cruz, Emily K Wright, Fabiyola Selvaraj, Timothy H Florin

J Gastroenterol Hepatol· June 2017

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Microbial metabolism of thiopurines: A method to measure thioguanine nucleotides.
Ramya Movva, Michael Lobb, Páraic Ó Cuív, Timothy H J Florin, John A Duley

J Microbiol Methods· September 2016

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High Fat Diets Induce Colonic Epithelial Cell Stress and Inflammation that is Reversed by IL-22.
Max Gulhane, Lydia Murray, Rohan Lourie, Hui Tong, Yong H Sheng, Timothy H Florin

Sci Rep· June 2016

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Enteroliths in a Kock continent ileostomy: case report and review of the literature.
Hadi Moattar, Jakob Begun, Timothy Florin

Endoscopy· January 2016

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