Publications by authors named "Timothy Heath"

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Efficacy and Safety of COVID-19 Convalescent Plasma in Hospitalized Patients: A Randomized Clinical Trial.
Mila B Ortigoza, Hyunah Yoon, Keith S Goldfeld, Andrea B Troxel, Johanna P Daily, Timothy R Heath

JAMA Intern Med· February 2022

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Durable multitransgene expression in vivo using systemic, nonviral DNA delivery.
Chakkrapong Handumrongkul, Alice L Ye, Stephen A Chmura, Liliana Soroceanu, Marissa Mack, Timothy D Heath

Sci Adv· November 2019

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Postoperative Analgesia Provided by Liposomal Hydromorphone in Client-Owned Dogs Undergoing Limb Amputation.
Lisa Krugner-Higby, Lesley J Smith, Brynn Schmidt, Paulo V Steagall, Carolyn Brown, Timothy D Heath

J Am Anim Hosp Assoc· August 2016

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Indirect assessment of neutralizing anti-drug antibodies utilizing pharmacokinetic assay data.
Christian Vettermann, Jessica Ortiz, Stephanie Lee, Sergio Sanchez, Hannah P Victor, Timothy Heath

J Immunol Methods· February 2016

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A Novel Loading Method for Doxycycline Liposomes for Intracellular Drug Delivery: Characterization of In Vitro and In Vivo Release Kinetics and Efficacy in a J774A.1 Cell Line Model of Mycobacterium smegmatis Infection.
Rebekah K Franklin, Sarah A Marcus, Adel M Talaat, Butch K KuKanich, Ruth Sullivan, Timothy D Heath

Drug Metab Dispos· August 2015

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Pharmacokinetics of ammonium sulfate gradient loaded liposome-encapsulated oxymorphone and hydromorphone in healthy dogs.
Lesley J Smith, Butch K Kukanich, Lisa A Krugner-Higby, Brynn H Schmidt, Timothy D Heath

Vet Anaesth Analg· September 2013

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Pharmacokinetics of long-acting nalbuphine decanoate after intramuscular administration to Hispaniolan Amazon parrots (Amazona ventralis).
David Sanchez-Migallon Guzman, Butch KuKanich, Timothy D Heath, Lisa A Krugner-Higby, Steven A Barker

Am J Vet Res· February 2013

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Antinociceptive effects of long-acting nalbuphine decanoate after intramuscular administration to Hispaniolan Amazon parrots (Amazona ventralis).
David Sanchez-Migallon Guzman, Jana M Braun, Paulo V M Steagall, Nicholas S Keuler, Timothy D Heath

Am J Vet Res· February 2013

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Pharmacokinetics and behavioral effects of liposomal hydromorphone suitable for perioperative use in rhesus macaques.
Lisa Krugner-Higby, Butch KuKanich, Brynn Schmidt, Timothy D Heath, Carolyn Brown

Psychopharmacology (Berl)· August 2011

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Experimental pharmacodynamics and analgesic efficacy of liposome-encapsulated hydromorphone in dogs.
Lisa Krugner-Higby, Lesley Smith, Brynn Schmidt, Laura Wunsch, Andrea Smetana, Timothy D Heath

J Am Anim Hosp Assoc· August 2011

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Epidural administration of liposome-encapsulated hydromorphone provides extended analgesia in a rodent model of stifle arthritis.
Jennifer R Schmidt, Lisa Krugner-Higby, Timothy D Heath, Ruth Sullivan, Lesley J Smith

J Am Assoc Lab Anim Sci· July 2011

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A mathematical relationship for hydromorphone loading into liposomes with trans-membrane ammonium sulfate gradients.
Sheng Tu, Tamara McGinnis, Lisa Krugner-Higby, Timothy D Heath

J Pharm Sci· June 2010

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Evaluation of phospholipid and liposomal S-adenosyl methionine for the treatment of liver injury in a murine model.
Eric J Wagner, Carolyn S Brown, Jennifer R Mather, Cecilia Scholcoff, Lisa Krugner-Higby, Timothy D Heath

J Pharm Sci· April 2010

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Analgesic effects of carprofen and liposome-encapsulated butorphanol tartrate in Hispaniolan parrots (Amazona ventralis) with experimentally induced arthritis.
Joanne R Paul-Murphy, Kurt K Sladky, Lisa A Krugner-Higby, Ben R Stading, Julia M Klauer, Timothy D Heath

Am J Vet Res· October 2009

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Evaluation of liposome-encapsulated butorphanol tartrate for alleviation of experimentally induced arthritic pain in green-cheeked conures (Pyrrhura molinae).
Joanne R Paul-Murphy, Lisa A Krugner-Higby, Renee L Tourdot, Kurt K Sladky, Julia M Klauer, Timothy D Heath

Am J Vet Res· October 2009

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Renal organic anion transporter-mediated drug-drug interaction between gemcabene and quinapril.
Haodan Yuan, Bo Feng, Ying Yu, Jonathan Chupka, Jenny Y Zheng, Timothy G Heath

J Pharmacol Exp Ther· July 2009

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Pharmacokinetics and behavioral effects of an extended-release, liposome-encapsulated preparation of oxymorphone in rhesus macaques.
Lisa Krugner-Higby, Butch KuKanich, Brynn Schmidt, Timothy D Heath, Carolyn Brown

J Pharmacol Exp Ther· July 2009

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Endogenous ethanolamide analysis in human plasma using HPLC tandem MS with electrospray ionization.
Joe Palandra, Jeff Prusakiewicz, Josef S Ozer, Yanhua Zhang, Timothy G Heath

J Chromatogr B Analyt Technol Biomed Life Sci· July 2009

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Application of stable isotope methodology in the evaluation of the pharmacokinetics of (S,S)-3-[3-(methylsulfonyl)phenyl]-1-propylpiperidine hydrochloride in rats.
Shinji Yamazaki, Lisa N Toth, Emi Kimoto, Janice Bower, Judith Skaptason, Timothy G Heath

Drug Metab Dispos· May 2009

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Liposome dependent delivery of S-adenosyl methionine to cells by liposomes: a potential treatment for liver disease.
Eric J Wagner, Lisa Krugner-Higby, Timothy D Heath

J Pharm Sci· February 2009

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Absolute quantification of multidrug resistance-associated protein 2 (MRP2/ABCC2) using liquid chromatography tandem mass spectrometry.
Na Li, Olga V Nemirovskiy, Yiqun Zhang, Haodan Yuan, Jianming Mo, Timothy G Heath

Anal Biochem· September 2008

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A single dose of liposome-encapsulated hydromorphone provides extended analgesia in a rat model of neuropathic pain.
Lesley J Smith, Janice R Valenzuela, Lisa A Krugner-Higby, Carolyn Brown, Timothy D Heath

Comp Med· December 2006

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Serum concentrations and analgesic effects of liposome-encapsulated and standard butorphanol tartrate in parrots.
Kurt K Sladky, Lisa Krugner-Higby, Elizabeth Meek-Walker, Timothy D Heath, Joanne Paul-Murphy

Am J Vet Res· May 2006

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Predicting in vivo drug interactions from in vitro drug discovery data.
Larry C Wienkers, Timothy G Heath

Nat Rev Drug Discov· October 2005

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Methodology and experimental design for the study of liposome-dependent drugs.
Timothy D Heath

Methods Enzymol· August 2005

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