Publications by authors named "Timothy M Block"

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Small molecule HBV RNA destabilizing drugs: Drugs of the future or compounds from the past?
Timothy M Block, Dimitar Gotchev, Yanming Du

Antiviral Res· December 2025

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Detection of Circulating mRNA Variants in Hepatocellular Carcinoma Patients Using Targeted RNAseq.
Daniel Zezulinski, Maarouf A Hoteit, David E Kaplan, Angela Simeone, Tingting Zhan, Timothy M Block

Liver Cancer· October 2025

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HBV-specific T-cell function is nonenhanced by tenofovir-induced decline in HBV viremia or HBsAg titer in chronic hepatitis B.
Daniel Traum, David K Wong, Daryl T Lau, Richard K Sterling, Norah A Terrault, Timothy M Block

Hepatol Commun· June 2025

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New potent HBV replication inhibitors for the management of chronic hepatitis B are needed.
Timothy M Block, Ju-Tao Guo, Fabien Zoulim, Charles M Rice, Chloe L Thio, Peter D Block

Nat Rev Gastroenterol Hepatol· March 2025

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A roadmap for serum biomarkers for hepatitis B virus: current status and future outlook.
Anna Kramvis, Kyong-Mi Chang, Maura Dandri, Patrizia Farci, Dieter Glebe, Timothy M Block

Nat Rev Gastroenterol Hepatol· November 2022

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Letter to the editor: Importance of universal screening for chronic hepatitis B infection in adults in the United States.
Chari Cohen, Kate Moraras, Michalea Jackson, Maureen Kamischke, Robert G Gish, Timothy M Block

Hepatology· April 2022

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Prospects for the Global Elimination of Hepatitis B.
Timothy M Block, Kyong-Mi Chang, Ju-Tao Guo

Annu Rev Virol· September 2021

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Hepatoselective Dihydroquinolizinone Bis-acids for HBsAg mRNA Degradation.
Nicky Hwang, Liren Sun, Daisy Noe, Patrick Y S Lam, Tianlun Zhou, Timothy M Block

ACS Med Chem Lett· July 2021

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Common concerns, barriers to care, and the lived experience of individuals with hepatitis B: a qualitative study.
Catherine Freeland, Sean Farrell, Priyanka Kumar, Maureen Kamischke, Michaela Jackson, Timothy M Block

BMC Public Health· May 2021

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Highly multiplexed 2-dimensional imaging mass cytometry analysis of HBV-infected liver.
Daniel Traum, Yue J Wang, Kathleen B Schwarz, Jonathan Schug, David Kh Wong, Timothy M Block

JCI Insight· April 2021

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Host RNA quality control as a hepatitis B antiviral target.
Timothy M Block, John A T Young, Hassan Javanbakht, Michael J Sofia, Tianlun Zhou

Antiviral Res· February 2021

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Application of the Doylestown algorithm for the early detection of hepatocellular carcinoma.
Anand S Mehta, Daryl T-Y Lau, Mengjun Wang, Aysha Aslam, Bilal Nasir, Timothy M Block

PLoS One· February 2019

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Host functions used by hepatitis B virus to complete its life cycle: Implications for developing host-targeting agents to treat chronic hepatitis B.
Bidisha Mitra, Roshan J Thapa, Haitao Guo, Timothy M Block

Antiviral Res· October 2018

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Correction: Application of the Doylestown algorithm for the early detection of hepatocellular carcinoma.
Anand S Mehta, Daryl T-Y Lau, Mengjun Wang, Aysha Aslam, Bilal Nasir, Timothy M Block

PLoS One· October 2018

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Do hepatitis B virus surface antigens have any role in viral carcinogenesis?
Ju-Tao Guo, Timothy M Block

Hepatology· September 2018

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Disease Pathways and Mechanisms of Potential Drug Targets.
Marc G Ghany, Timothy M Block

Clin Liver Dis (Hoboken)· July 2018

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Research priorities for the discovery of a cure for chronic hepatitis B: Report of a workshop.
Timothy M Block, Harvey Alter, Nathaniel Brown, Alan Brownstein, Carol Brosgart

Antiviral Res· February 2018

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Enhancing the antiviral potency of ER α-glucosidase inhibitor IHVR-19029 against hemorrhagic fever viruses in vitro and in vivo.
Julia Ma, Xuexiang Zhang, Veronica Soloveva, Travis Warren, Fang Guo, Timothy M Block

Antiviral Res· February 2018

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Identification of fucosylated Fetuin-A as a potential biomarker for cholangiocarcinoma.
Lucy Betesh, Mary Ann Comunale, Mengjun Wang, Hongyan Liang, Julie Hafner, Timothy M Block

Proteomics Clin Appl· September 2017

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Discovery and Mechanistic Study of Benzamide Derivatives That Modulate Hepatitis B Virus Capsid Assembly.
Shuo Wu, Qiong Zhao, Pinghu Zhang, John Kulp, Lydia Hu, Timothy M Block

J Virol· August 2017

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Use of Current and New Endpoints in the Evaluation of Experimental Hepatitis B Therapeutics.
Timothy M Block, Stephen Locarnini, Brian J McMahon, Barbara Rehermann, Marion G Peters

Clin Infect Dis· May 2017

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Interferon-inducible ribonuclease ISG20 inhibits hepatitis B virus replication through directly binding to the epsilon stem-loop structure of viral RNA.
Yuanjie Liu, Hui Nie, Richeng Mao, Bidisha Mitra, Dawei Cai, Timothy M Block

PLoS Pathog· April 2017

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Ester Prodrugs of IHVR-19029 with Enhanced Oral Exposure and Prevention of Gastrointestinal Glucosidase Interaction.
Julia Ma, Shuo Wu, Xuexiang Zhang, Fang Guo, Katherine Yang, Timothy M Block

ACS Med Chem Lett· February 2017

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A Novel Benzodiazepine Compound Inhibits Yellow Fever Virus Infection by Specifically Targeting NS4B Protein.
Fang Guo, Shuo Wu, Justin Julander, Julia Ma, Xuexiang Zhang, Timothy M Block

J Virol· December 2016

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Evolving New Strategies for the Medical Management of Chronic Hepatitis B Virus Infection.
Timothy M Block, Tianlun Zhou, Nikhil Anbarasan, Robert Gish

Gastroenterol Hepatol (N Y)· November 2016

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