Publications by authors named "Yanming Du"

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Small molecule HBV RNA destabilizing drugs: Drugs of the future or compounds from the past?
Timothy M Block, Dimitar Gotchev, Yanming Du

Antiviral Res· December 2025

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Hepato-selective dihydroquinolizinones active against hepatitis A virus in vitro and in vivo.
Ichiro Misumi, Zhizhou Yue, Zhengyuan Jiang, Anilkumar Karampoori, Jason K Whitmire, Yanming Du

Antiviral Res· May 2025

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Modes of action of a small molecule antiviral compound targeting yellow fever virus NS4B protein.
Fuxuan Wang, Zhao Gao, Bo Chen, Zhengyuan Jiang, David M Renner, Yanming Du

Proc Natl Acad Sci U S A· May 2025

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Discovery of hepatitis B virus subviral particle biogenesis inhibitors from a bioactive compound library.
Biplav Shrestha, Sisi Yang, Lauren Griffith, Julia Ma, Fuxuan Wang, Yanming Du

Antiviral Res· August 2024

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"PROTAC" modified dihydroquinolizinones (DHQs) that cause degradation of PAPD-5 and inhibition of hepatitis A virus and hepatitis B virus, in vitro.
You Li, Nicky Hwang, Andrew Snedeker, Stanley M Lemon, Daisy Noe, Yanming Du

Bioorg Med Chem Lett· April 2024

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A cyclin D1 intrinsically disordered domain accesses modified histone motifs to govern gene transcription.
Xuanmao Jiao, Gabriele Di Sante, Mathew C Casimiro, Agnes Tantos, Anthony W Ashton, Yanming Du

Oncogenesis· January 2024

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Identification of novel tetrahydroquinoxaline derived phenyl ureas as modulators of the hepatitis B virus nucleocapsid assembly.
Nicky Hwang, Shuo Wu, Haiqun Ban, Huixin Luo, Julia Ma, Na Du, Yanming Du

Eur J Med Chem· November 2023

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The Renaissance of CDK Inhibitors in Breast Cancer Therapy: An Update on Clinical Trials and Therapy Resistance.
Mary Abdelmalak, Rajanbir Singh, Mohammed Anwer, Pavel Ivanchenko, Amritdeep Randhawa, Yanming Du

Cancers (Basel)· November 2022

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4-Oxooctahydroquinoline-1(2H)-carboxamides as hepatitis B virus (HBV) capsid core protein assembly modulators.
Nicky Hwang, Haiqun Ban, Shuo Wu, Kelly McGuire, Ellen Hernandez, Yanming Du

Bioorg Med Chem Lett· February 2022

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A yellow fever virus NS4B inhibitor not only suppresses viral replication, but also enhances the virus activation of RIG-I-like receptor-mediated innate immune response.
Zhao Gao, Xuexiang Zhang, Lin Zhang, Shuo Wu, Julia Ma, Yanming Du

PLoS Pathog· January 2022

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Identification of hepatitis B virus core protein residues critical for capsid assembly, pgRNA encapsidation and resistance to capsid assembly modulators.
Yue Luo, Junjun Cheng, Zhanying Hu, Haiqun Ban, Shuo Wu, Yanming Du

Antiviral Res· July 2021

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Hepatoselective Dihydroquinolizinone Bis-acids for HBsAg mRNA Degradation.
Nicky Hwang, Liren Sun, Daisy Noe, Patrick Y S Lam, Tianlun Zhou, Yanming Du

ACS Med Chem Lett· July 2021

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Synthesis of 4-oxotetrahydropyrimidine-1(2H)-carboxamides derivatives as capsid assembly modulators of hepatitis B virus.
Nicky Hwang, Haiqun Ban, Junjun Chen, Julia Ma, Hui Liu, Yanming Du

Med Chem Res· January 2021

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Identification of a 3-β-homoalanine conjugate of brusatol with reduced toxicity in mice.
Nicky Hwang, Yonggang Pei, Jason Clement, Erle S Robertson, Yanming Du

Bioorg Med Chem Lett· December 2020

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Targeting the multifunctional HBV core protein as a potential cure for chronic hepatitis B.
Usha Viswanathan, Nagraj Mani, Zhanying Hu, Haiqun Ban, Yanming Du

Antiviral Res· October 2020

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Quassinoid analogs with enhanced efficacy for treatment of hematologic malignancies target the PI3Kγ isoform.
Yonggang Pei, Nicky Hwang, Fengchao Lang, Lanlan Zhou, Josiah Hiu-Yuen Wong, Yanming Du

Commun Biol· May 2020

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Downregulation of histone methyltransferase SET8 inhibits progression of hepatocellular carcinoma.
Jianhua Wu, Kuangyuan Qiao, Yanming Du, Xiaoyun Zhang, Haichao Cheng

Sci Rep· March 2020

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Discovery and Mechanistic Study of a Novel Human-Stimulator-of-Interferon-Genes Agonist.
Xiaohui Zhang, Bowei Liu, Liudi Tang, Qing Su, Nicky Hwang, Zhongping Duan, Yanming Du

ACS Infect Dis· July 2019

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Discovery of Novel Hepatitis B Virus Nucleocapsid Assembly Inhibitors.
Xuexiang Zhang, Junjun Cheng, Julia Ma, Zhanying Hu, Shuo Wu, Yanming Du

ACS Infect Dis· May 2019

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Enhancing the antiviral potency of ER α-glucosidase inhibitor IHVR-19029 against hemorrhagic fever viruses in vitro and in vivo.
Julia Ma, Xuexiang Zhang, Veronica Soloveva, Travis Warren, Fang Guo, Yanming Du

Antiviral Res· February 2018

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A cell-based high throughput screening assay for the discovery of cGAS-STING pathway agonists.
Bowei Liu, Liudi Tang, Xiaohui Zhang, Julia Ma, Mohit Sehgal, Yanming Du

Antiviral Res· November 2017

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HBV core protein allosteric modulators differentially alter cccDNA biosynthesis from de novo infection and intracellular amplification pathways.
Fang Guo, Qiong Zhao, Muhammad Sheraz, Junjun Cheng, Yonghe Qi, Yanming Du

PLoS Pathog· September 2017

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Discovery and Mechanistic Study of Benzamide Derivatives That Modulate Hepatitis B Virus Capsid Assembly.
Shuo Wu, Qiong Zhao, Pinghu Zhang, John Kulp, Lydia Hu, Yanming Du

J Virol· August 2017

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Ester Prodrugs of IHVR-19029 with Enhanced Oral Exposure and Prevention of Gastrointestinal Glucosidase Interaction.
Julia Ma, Shuo Wu, Xuexiang Zhang, Fang Guo, Katherine Yang, Yanming Du

ACS Med Chem Lett· February 2017

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Novel substituted aminothiazoles as potent and selective anti-hepatocellular carcinoma agents.
Huagang Lu, John Rogowskyj, Wenquan Yu, Anu Venkatesh, Noshena Khan, Yanming Du

Bioorg Med Chem Lett· December 2016

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