Publications by authors named "Timothy Olah"

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Quantification of Linrodostat and its metabolites: Overcoming bioanalytical challenges in support of a discovery Indoleamine 2,3 dioxygenase program.
Lorell N Discenza, Aaron Balog, Christine Huang, Robin Moore, Asoka Ranasinghe, Timothy V Olah

J Chromatogr B Analyt Technol Biomed Life Sci· September 2022

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Novel techniques and the new age of biomarkers: panel discussion report.
Stephanie Pasas-Farmer, Chris James, Christine Fandozzi, Dominic Warrino, Rob Durham, Timothy Olah

Bioanalysis· May 2021

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Calibrator material selection: a key criteria during biomarker assay method development.
Sai P Thankamony, Rong Liu, Jon E Peterson, Rasa Santockyte, Timothy Olah

Bioanalysis· May 2021

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An integrated Qual/Quan strategy for ganglioside lipidomics using high-resolution mass spectrometry and Skyline software.
Asoka Ranasinghe, Eugene Ciccimaro, Celia D'Arienzo, Timothy V Olah, Paul Ponath

Rapid Commun Mass Spectrom· April 2021

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2020 White Paper on Recent Issues in Bioanalysis: BMV of Hybrid Assays, Acoustic MS, HRMS, Data Integrity, Endogenous Compounds, Microsampling and Microbiome ( - Recommendations on Industry/Regulators Consensus on BMV of Biotherapeutics by LCMS, Advanced Application in Hybrid Assays, Regulatory Challenges in Mass Spec, Innovation in Small Molecules, Peptides and Oligos).
Hendrik Neubert, Stephen C Alley, Anita Lee, Wenying Jian, Michael Buonarati, Timothy Olah

Bioanalysis· February 2021

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Quantification of surrogate monoclonal antibodies in mouse serum using LC-MS/MS.
John T Mehl, France Landry, Lorell Discenza, Bogdan Sleczka, Qihong Zhao, Timothy V Olah

Bioanalysis· February 2021

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Immunoaffinity microflow liquid chromatography/tandem mass spectrometry for the quantitation of PD1 and PD-L1 in human tumor tissues.
Yongxin Zhu, Jacob Zalaznick, Bogdan Sleczka, Karen Parrish, Zheng Yang, Timothy Olah

Rapid Commun Mass Spectrom· October 2020

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Ultrahigh-Throughput and Chromatography-Free Bioanalysis of Polar Analytes with Acoustic Ejection Mass Spectrometry.
Andrew Wagner, Jun Zhang, Chang Liu, Thomas R Covey, Timothy V Olah

Anal Chem· October 2020

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Immunoaffinity enrichment LC-MS/MS quantitation of CDH17 in tissues.
Christian Caporuscio, Derek Holmes, Timothy V Olah, Petia Shipkova

Bioanalysis· October 2020

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A peptide immunoaffinity LC-MS/MS strategy for quantifying the GPCR protein, S1PR1 in human colon biopsies.
Hongwei Zhang, Eugene Ciccimaro, Jacob Zalaznick, Bogdan G Sleczka, Laurence Menard, Timothy V Olah

Bioanalysis· September 2020

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LC/MS/MS-based quantitation of pig and human S100A1 protein in cardiac tissues: Application to gene therapy.
Bogdan G Sleczka, Paul C Levesque, Leonard P Adam, Timothy V Olah, Petia Shipkova

Anal Biochem· August 2020

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Protein Biomarker Quantification by Immunoaffinity Liquid Chromatography-Tandem Mass Spectrometry: Current State and Future Vision.
Hendrik Neubert, Christopher M Shuford, Timothy V Olah, Fabio Garofolo, Gary A Schultz

Clin Chem· February 2020

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2019 White Paper on Recent Issues in Bioanalysis: Chromatographic Assays (Part 1 - Innovation in Small Molecules and Oligonucleotides & Mass Spectrometric Method Development Strategies for Large Molecule Bioanalysis).
Christine Fandozzi, Christopher Evans, Amanda Wilson, Dian Su, Melanie Anderson, Timothy Olah

Bioanalysis· November 2019

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2018 White Paper on Recent Issues in Bioanalysis: focus on immunogenicity assays by hybrid LBA/LCMS and regulatory feedback (Part 2 - PK, PD & ADA assays by hybrid LBA/LCMS & regulatory agencies' inputs on bioanalysis, biomarkers and immunogenicity).
Hendrik Neubert, Timothy Olah, Anita Lee, Stephanie Fraser, Robert Dodge

Bioanalysis· December 2018

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Fucosyl monosialoganglioside: Quantitative analysis of specific potential biomarkers of lung cancer in biological matrices using immunocapture extraction/tandem mass spectrometry.
Asoka Ranasinghe, John Mehl, Celia D'Arienzo, Fizal Nabbie, Christopher Chiu, Timothy Olah

Rapid Commun Mass Spectrom· September 2018

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Analytical considerations for quantitative LC-MS strategies for measuring antibody drug-target engagement in tissues.
Petia Shipkova, Eugene Ciccimaro, Timothy V Olah

Bioanalysis· December 2017

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A novel function of CXCL10 in mediating monocyte production of proinflammatory cytokines.
Qihong Zhao, Taeg Kim, Jian Pang, Wendy Sun, Xiaoxia Yang, Timothy Olah

J Leukoc Biol· November 2017

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Immunoaffinity LC-MS/MS for quantitative determination of a free and total protein target as a target engagement biomarker.
Hongwei Zhang, Huidong Gu, Petia Shipkova, Eugene Ciccimaro, Huadong Sun, Timothy V Olah

Bioanalysis· October 2017

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Antibody Drug-Target Engagement Measurement in Tissue Using Quantitative Affinity Extraction Liquid Chromatography-Mass Spectrometry: Method Development and Qualification.
Eugene Ciccimaro, Yongxin Zhu, Dmitry Ostanin, Suzanne Suchard, Jamus MacGuire, Timothy Olah

Anal Chem· May 2017

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2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV): (Part 2 - Hybrid LBA/LCMS and input from regulatory agencies).
An Song, Anita Lee, Fabio Garofolo, Surinder Kaur, Jeff Duggan, Timothy Olah

Bioanalysis· December 2016

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Quantification of in vivo site-specific Asp isomerization and Asn deamidation of mAbs in animal serum using IP-LC-MS.
John T Mehl, Bogdan G Sleczka, Eugene F Ciccimaro, Alexander T Kozhich, Deb G Gilbertson, Timothy V Olah

Bioanalysis· August 2016

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Antibody-drug conjugate bioanalysis using LB-LC-MS/MS hybrid assays: strategies, methodology and correlation to ligand-binding assays.
Jian Wang, Huidong Gu, Ang Liu, Alexander Kozhich, Vangipuram Rangan, Timothy V Olah

Bioanalysis· July 2016

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The utility of stable isotope labeled (SIL) analogues in the bioanalysis of endogenous compounds by LC-MS applied to the study of bile acids in a metabolomics assay.
Joanna J Zheng, Eric E Shields, Kimberly J Snow, David M Nelson, Timothy V Olah

Anal Biochem· June 2016

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Ultrasensitive quantitative LC-MS/MS of an inhibitor of apoptosis protein's antagonist in plasma using protein target affinity extraction.
Lorell N Discenza, Georgia Cornelius, Jinping Gan, Nicolas Szapiel, Randy L Talbott, Timothy V Olah

Bioanalysis· February 2016

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LC-MS/MS multiplexed assay for the quantitation of a therapeutic protein BMS-986089 and the target protein Myostatin.
Yongxin Zhu, Celia D'Arienzo, Zhen Lou, Alexander Kozhich, Malavi Madireddi, Timothy V Olah

Bioanalysis· February 2016

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