Publications by authors named "Timothy Waybright"

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Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity.
Jason J Kwon, Julien Dilly, Shengwu Liu, Eejung Kim, Yuemin Bian, Timothy J Waybright

bioRxiv· October 2024

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Producing recombinant proteins in Vibrio natriegens.
Matthew Smith, José Sánchez Hernández, Simon Messing, Nitya Ramakrishnan, Brianna Higgins, Timothy Waybright

Microb Cell Fact· July 2024

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Adapting recombinant bacterial alkaline phosphatase for nucleotide exchange of small GTPases.
Peter H Frank, Min Hong, Brianna Higgins, Shelley Perkins, Troy Taylor, Timothy Waybright

Protein Expr Purif· June 2024

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Nucleotide Exchange on RAS Proteins Using Hydrolysable and Non-hydrolysable Nucleotides.
Timothy Waybright, Andrew G Stephen

Methods Mol Biol· April 2024

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Comparative analysis of KRAS4a and KRAS4b splice variants reveals distinctive structural and functional properties.
Matthew J Whitley, Timothy H Tran, Megan Rigby, Ming Yi, Srisathiyanarayanan Dharmaiah, Timothy J Waybright

Sci Adv· February 2024

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Allosteric Regulation of Switch-II Domain Controls KRAS Oncogenicity.
Moon Hee Yang, Timothy H Tran, Bethany Hunt, Rebecca Agnor, Christian W Johnson, Timothy J Waybright

Cancer Res· October 2023

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GAP positions catalytic H-Ras residue Q61 for GTP hydrolysis in molecular dynamics simulations, complicating chemical rescue of Ras deactivation.
Lara A Patel, Timothy J Waybright, Andrew G Stephen, Chris Neale

Comput Biol Chem· June 2023

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Biochemical and structural analyses reveal that the tumor suppressor neurofibromin (NF1) forms a high-affinity dimer.
Mukul Sherekar, Sae-Won Han, Rodolfo Ghirlando, Simon Messing, Matthew Drew, Timothy Waybright

J Biol Chem· January 2020

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Fully Processed Recombinant KRAS4b: Isolating and Characterizing the Farnesylated and Methylated Protein.
Constance Agamasu, Peter Frank, Shelley Perkins, Timothy Waybright, Simon Messing

J Vis Exp· January 2020

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Structures of N-terminally processed KRAS provide insight into the role of N-acetylation.
Srisathiyanarayanan Dharmaiah, Timothy H Tran, Simon Messing, Constance Agamasu, William K Gillette, Timothy Waybright

Sci Rep· July 2019

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mTOR Inhibition Mitigates Enhanced mRNA Translation Associated with the Metastatic Phenotype of Osteosarcoma Cells In Vivo.
James J Morrow, Arnulfo Mendoza, Allyson Koyen, Michael M Lizardo, Ling Ren, Timothy J Waybright

Clin Cancer Res· December 2016

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Preparation of the low molecular weight serum proteome for mass spectrometry analysis.
Timothy J Waybright, King C Chan, Timothy D Veenstra, Zhen Xiao

Methods Mol Biol· March 2014

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Preparation of human cerebrospinal fluid for proteomics biomarker analysis.
Timothy J Waybright

Methods Mol Biol· February 2014

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Preparation of human serum for prolactin measurement by multiple reaction monitoring mass spectrometry.
Timothy J Waybright, Xia Xu, Jessica M Faupel-Badger, Zhen Xiao

Methods Mol Biol· February 2014

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Phosphorylation of centromeric histone H3 variant regulates chromosome segregation in Saccharomyces cerevisiae.
Lars Boeckmann, Yoshimitsu Takahashi, Wei-Chun Au, Prashant K Mishra, John S Choy, Timothy J Waybright

Mol Biol Cell· June 2013

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Pressure-assisted protein extraction: a novel method for recovering proteins from archival tissue for proteomic analysis.
Carol B Fowler, Timothy J Waybright, Timothy D Veenstra, Timothy J O'Leary, Jeffrey T Mason

J Proteome Res· April 2012

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Characterization of recombinant human IL-15 deamidation and its practical elimination through substitution of asparagine 77.
David F Nellis, Dennis F Michiel, Man-Shiow Jiang, Dominic Esposito, Richard Davis, Timothy J Waybright

Pharm Res· March 2012

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Molecular profiling of the human nasal epithelium: A proteomics approach.
Tânia Simões, Nuno Charro, Josip Blonder, Daniel Faria, Francisco M Couto, Timothy Waybright

J Proteomics· December 2011

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Cancer biomarker discovery: Opportunities and pitfalls in analytical methods.
Haleem J Issaq, Timothy J Waybright, Timothy D Veenstra

Electrophoresis· April 2011

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Characterization of the human ventricular cerebrospinal fluid proteome obtained from hydrocephalic patients.
Timothy Waybright, Anthony M Avellino, Richard G Ellenbogen, Bradley J Hollinger, Timothy D Veenstra

J Proteomics· April 2010

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Overcoming problems of compound storage in DMSO: solvent and process alternatives.
Timothy J Waybright, John R Britt, Thomas G McCloud

J Biomol Screen· July 2009

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Analytical and statistical approaches to metabolomics research.
Haleem J Issaq, Que N Van, Timothy J Waybright, Gary M Muschik, Timothy D Veenstra

J Sep Sci· July 2009

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Site specific conjugation of fluoroprobes to the remodeled Fc N-glycans of monoclonal antibodies using mutant glycosyltransferases: application for cell surface antigen detection.
Elizabeth Boeggeman, Boopathy Ramakrishnan, Marta Pasek, Maria Manzoni, Anu Puri, Timothy J Waybright

Bioconjug Chem· June 2009

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Bringing protein biomarker discovery to the clinic.
Timothy J Waybright, Timothy D Veenstra

Expert Rev Mol Diagn· May 2009

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Bioconjugation and detection of lactosamine moiety using alpha1,3-galactosyltransferase mutants that transfer C2-modified galactose with a chemical handle.
Marta Pasek, Boopathy Ramakrishnan, Elizabeth Boeggeman, Maria Manzoni, Timothy J Waybright

Bioconjug Chem· March 2009

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