Publications by authors named "Toby Kent"

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Evaluating the efficacy of upadacitinib in patients with moderate rheumatoid arthritis: a post-hoc analysis of the SELECT phase 3 trials.
Philip G Conaghan, Karel Pavelka, Song-Chou Hsieh, Terri-Leigh Bonnington, Toby C Kent

Rheumatol Adv Pract· February 2023

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Upadacitinib response rates in patients with psoriatic arthritis enrolled in the SELECT-PsA-1 and SELECT-PsA-2 trials assessed according to modified PsARC.
Laura C Coates, Toby Garrood, Nicola Gullick, Philip Helliwell, Toby Kent

Rheumatology (Oxford)· December 2022

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Targeted literature review of current treatments and unmet need in moderate rheumatoid arthritis in the United Kingdom.
Peter C Taylor, Matthew Woods, Catherine Rycroft, Priya Patel, Sophee Blanthorn-Hazell, Toby Kent

Rheumatology (Oxford)· November 2021

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Impact of Ixekizumab Treatment on Itch and Psoriasis Area and Severity Index in Patients with Moderate-to-Severe Plaque Psoriasis: An Integrated Analysis of Two Phase III Randomized Studies.
Gil Yosipovitch, Adam Reich, Martin Steinhoff, Anke Beselin, Toby Kent

Dermatol Ther (Heidelb)· December 2018

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The inhibition of human lung fibroblast proliferation and differentiation by Gs-coupled receptors is not predicted by the magnitude of cAMP response.
Maxine J Roberts, Rebecca E Broome, Toby C Kent, Steven J Charlton, Elizabeth M Rosethorne

Respir Res· April 2018

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Comparing the cardiovascular therapeutic indices of glycopyrronium and tiotropium in an integrated rat pharmacokinetic, pharmacodynamic and safety model.
Alexandre Trifilieff, Brian T Ethell, David A Sykes, Kenny J Watson, Steve Collingwood, Toby C Kent

Toxicol Appl Pharmacol· August 2015

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Functional desensitization of the β 2 adrenoceptor is not dependent on agonist efficacy.
Elizabeth M Rosethorne, Michelle E Bradley, Toby C Kent, Steven J Charlton

Pharmacol Res Perspect· February 2015

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High throughput mutagenesis for identification of residues regulating human prostacyclin (hIP) receptor expression and function.
Anke Bill, Elizabeth M Rosethorne, Toby C Kent, Lindsay Fawcett, Lynn Burchell

PLoS One· January 2015

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The development of automated patch clamp assays for canonical transient receptor potential channels TRPC3, 6, and 7.
Mark McPate, Gurdip Bhalay, Martin Beckett, Sian Fairbrother, Martin Gosling, Toby Kent

Assay Drug Dev Technol· June 2014

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The antiallergic mast cell stabilizers lodoxamide and bufrolin as the first high and equipotent agonists of human and rat GPR35.
Amanda E MacKenzie, Gianluigi Caltabiano, Toby C Kent, Laura Jenkins, Jennifer E McCallum

Mol Pharmacol· January 2014

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The use of cold plasma technology to reduce carryover in screening assays.
Mohammed Akhlaq, Elizabeth M Rosethorne, Afrah Sattikar, Toby C Kent

J Lab Autom· August 2013

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The Influence of receptor kinetics on the onset and duration of action and the therapeutic index of NVA237 and tiotropium.
David A Sykes, Mark R Dowling, Juliet Leighton-Davies, Toby C Kent, Lindsay Fawcett

J Pharmacol Exp Ther· November 2012

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Quantitative GPCR and ion channel transcriptomics in primary alveolar macrophages and macrophage surrogates.
Paul J Groot-Kormelink, Lindsay Fawcett, Paul D Wright, Martin Gosling, Toby C Kent

BMC Immunol· October 2012

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G-protein-coupled receptor heterodimerization: assay technologies to clinical significance.
Toby Kent, Cheryl McAlpine, Sahar Sabetnia, Jeremy Presland

Curr Opin Drug Discov Devel· September 2007

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Development of a generic dual-reporter gene assay for screening G-protein-coupled receptors.
Toby C Kent, Kevin S J Thompson, Louise H Naylor

J Biomol Screen· August 2005

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The effect of ICER on screening methods involving CRE-mediated reporter gene expression.
Daniel M Kemp, Samantha E George, Toby C Kent, Peter J Bungay, Louise H Naylor

J Biomol Screen· April 2002

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