Publications by authors named "Todd D Armstrong"

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Spatial proteomics and transcriptomics reveal early immune cell organization in pancreatic intraepithelial neoplasia.
Melissa R Lyman, Jacob T Mitchell, Sidharth Raghavan, Luciane T Kagohara, Amanda L Huff, Todd D Armstrong

JCI Insight· August 2025

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Mesothelin CAR T Cells Secreting Anti-FAP/Anti-CD3 Molecules Efficiently Target Pancreatic Adenocarcinoma and its Stroma.
Marc Wehrli, Samantha Guinn, Filippo Birocchi, Adam Kuo, Yi Sun, Todd D Armstrong

Clin Cancer Res· May 2024

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Fibroblasts in the Aged Pancreas Drive Pancreatic Cancer Progression.
Daniel J Zabransky, Yash Chhabra, Mitchell E Fane, Emma Kartalia, James M Leatherman, Todd D Armstrong

Cancer Res· April 2024

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Mimicking the breast metastatic microenvironment: characterization of a novel syngeneic model of HER2 breast cancer.
Aaron G Baugh, Edgar Gonzalez, Valerie H Narumi, Jesse Kreger, Yingtong Liu, Todd D Armstrong

bioRxiv· January 2024

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CD4 T cell-activating neoantigens enhance personalized cancer vaccine efficacy.
Amanda L Huff, Gabriella Longway, Jacob T Mitchell, Lalitya Andaloori, Emily Davis-Marcisak, Todd D Armstrong

JCI Insight· December 2023

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Implantation of a neoantigen-targeted hydrogel vaccine prevents recurrence of pancreatic adenocarcinoma after incomplete resection.
Daniel Delitto, Daniel J Zabransky, Fangluo Chen, Elizabeth D Thompson, Jacquelyn W Zimmerman, Todd D Armstrong

Oncoimmunology· January 2022

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Systemic inhibition of PTPN22 augments anticancer immunity.
Won Jin Ho, Sarah Croessmann, Jianping Lin, Zaw H Phyo, Soren Charmsaz, Todd D Armstrong

J Clin Invest· July 2021

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Multi-omic profiling of lung and liver tumor microenvironments of metastatic pancreatic cancer reveals site-specific immune regulatory pathways.
Won Jin Ho, Rossin Erbe, Ludmila Danilova, Zaw Phyo, Emma Bigelow, Todd D Armstrong

Genome Biol· May 2021

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Role of in silico structural modeling in predicting immunogenic neoepitopes for cancer vaccine development.
Neeha Zaidi, Mariya Soban, Fangluo Chen, Heather Kinkead, Jocelyn Mathew, Todd D Armstrong

JCI Insight· September 2020

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Robust antigen-specific CD8 T cell tolerance to a model prostate cancer neoantigen.
Zoila A Lopez-Bujanda, Matthew G Chaimowitz, Todd D Armstrong, Jeremy B Foote, Leisha A Emens

Oncoimmunology· September 2020

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Inhibition of miR-21 Regulates Mutant KRAS Effector Pathways and Intercepts Pancreatic Ductal Adenocarcinoma Development.
Nina J Chu, Robert A Anders, Elana J Fertig, Minwei Cao, Alexander C Hopkins, Todd D Armstrong

Cancer Prev Res (Phila)· July 2020

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Effects of B cell-activating factor on tumor immunity.
Mark Yarchoan, Won Jin Ho, Aditya Mohan, Yajas Shah, Teena Vithayathil, Todd D Armstrong

JCI Insight· May 2020

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MEK inhibition suppresses B regulatory cells and augments anti-tumor immunity.
Mark Yarchoan, Aditya A Mohan, Lauren Dennison, Teena Vithayathil, Amanda Ruggieri, Todd D Armstrong

PLoS One· March 2020

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Nanoparticle interactions with immune cells dominate tumor retention and induce T cell-mediated tumor suppression in models of breast cancer.
Preethi Korangath, James D Barnett, Anirudh Sharma, Elizabeth T Henderson, Jacqueline Stewart, Todd D Armstrong

Sci Adv· March 2020

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Dissecting the Stromal Signaling and Regulation of Myeloid Cells and Memory Effector T Cells in Pancreatic Cancer.
Alex B Blair, Victoria M Kim, Stephen T Muth, May Tun Saung, Nathalie Lokker, Todd D Armstrong

Clin Cancer Res· September 2019

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Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts.
Ela Elyada, Mohan Bolisetty, Pasquale Laise, William F Flynn, Elise T Courtois, Todd D Armstrong

Cancer Discov· August 2019

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Anti-pancreatic tumor efficacy of a Listeria-based, Annexin A2-targeting immunotherapy in combination with anti-PD-1 antibodies.
Victoria M Kim, Alex B Blair, Peter Lauer, Kelly Foley, Xu Che, Todd D Armstrong

J Immunother Cancer· May 2019

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Entinostat Converts Immune-Resistant Breast and Pancreatic Cancers into Checkpoint-Responsive Tumors by Reprogramming Tumor-Infiltrating MDSCs.
Brian J Christmas, Christine I Rafie, Alexander C Hopkins, Blake A Scott, Hayley S Ma, Todd D Armstrong

Cancer Immunol Res· December 2018

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Combining STING-based neoantigen-targeted vaccine with checkpoint modulators enhances antitumor immunity in murine pancreatic cancer.
Heather L Kinkead, Alexander Hopkins, Eric Lutz, Annie A Wu, Mark Yarchoan, Todd D Armstrong

JCI Insight· October 2018

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A STING Agonist Given with OX40 Receptor and PD-L1 Modulators Primes Immunity and Reduces Tumor Growth in Tolerized Mice.
Jeremy B Foote, Marleen Kok, James M Leatherman, Todd D Armstrong, Bridget C Marcinkowski

Cancer Immunol Res· June 2017

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Sorafenib combined with HER-2 targeted vaccination can promote effective T cell immunity in vivo.
Melek M E Sunay, Jeremy B Foote, James M Leatherman, Justin P Edwards, Todd D Armstrong

Int Immunopharmacol· May 2017

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Special Conference on Tumor Immunology and Immunotherapy: A New Chapter.
Katelyn T Byrne, Robert H Vonderheide, Elizabeth M Jaffee, Todd D Armstrong

Cancer Immunol Res· June 2015

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Nonviral oncogenic antigens and the inflammatory signals driving early cancer development as targets for cancer immunoprevention.
Nina J Chu, Todd D Armstrong, Elizabeth M Jaffee

Clin Cancer Res· April 2015

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Development of thyroglobulin antibodies after GVAX immunotherapy is associated with prolonged survival.
Alessandra De Remigis, Tanja D de Gruijl, Jennifer N Uram, Schey-Cherng Tzou, Shintaro Iwama, Todd D Armstrong

Int J Cancer· January 2015

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Apoptosis-regulated low-avidity cancer-specific CD8(+) T cells can be rescued to eliminate HER2/neu-expressing tumors by costimulatory agonists in tolerized mice.
Chelsea M Black, Todd D Armstrong, Elizabeth M Jaffee

Cancer Immunol Res· April 2014

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