Publications by authors named "Tom Goetze"

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Membrane binding of a cyanobacterial ESCRT-III protein crucially involves the helix α1-3 hairpin conserved in all superfamily members.
Lukas Schlösser, Mirka Kutzner, Nadja Hellmann, Denis Kiesewetter, Julia Bieber, Tom Goetze

Protein Sci· December 2025

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Development of ASIC1a ligand-gated ion channel drug screening assays across multiple automated patch clamp platforms.
John Ridley, Sam Manyweathers, Raymond Tang, Tom Goetze, Nadine Becker

Front Mol Neurosci· October 2022

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There is no F in APC: Using physiological fluoride-free solutions for high throughput automated patch clamp experiments.
Markus Rapedius, Alison Obergrussberger, Edward S A Humphries, Stephanie Scholz, Ilka Rinke-Weiss, Tom A Goetze

Front Mol Neurosci· August 2022

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The suitability of high throughput automated patch clamp for physiological applications.
Alison Obergrussberger, Ilka Rinke-Weiß, Tom A Goetze, Markus Rapedius, Nina Brinkwirth

J Physiol· January 2022

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Reliable identification of cardiac conduction abnormalities in drug discovery using automated patch clamp II: Best practices for Nav1.5 peak current in a high throughput screening environment.
Maria Giustina Rotordam, Alison Obergrussberger, Nina Brinkwirth, Kiyoshi Takasuna, Nadine Becker, Tom A Goetze

J Pharmacol Toxicol Methods· November 2021

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A general procedure to select calibration drugs for lab-specific validation and calibration of proarrhythmia risk prediction models: An illustrative example using the CiPA model.
Xiaomei Han, Mohammadreza Samieegohar, Bradley J Ridder, Wendy W Wu, Aaron Randolph, Tom A Goetze

J Pharmacol Toxicol Methods· September 2020

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A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm.
Bradley J Ridder, Derek J Leishman, Matthew Bridgland-Taylor, Mohammadreza Samieegohar, Xiaomei Han, Tom A Goetze

Toxicol Appl Pharmacol· May 2020

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Corrigendum to "A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm" [Toxicology and Applied Pharmacology volume 394C (2020) 114961].
Bradley J Ridder, Derek J Leishman, Matthew Bridgland-Taylor, Mohammadreza Samieegohar, Xiaomei Han, Tom A Goetze

Toxicol Appl Pharmacol· May 2020

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An update on the advancing high-throughput screening techniques for patch clamp-based ion channel screens: implications for drug discovery.
Alison Obergrussberger, Tom A Goetze, Nina Brinkwirth, Nadine Becker, Søren Friis

Expert Opin Drug Discov· March 2018

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Automated Patch Clamp Meets High-Throughput Screening: 384 Cells Recorded in Parallel on a Planar Patch Clamp Module.
Alison Obergrussberger, Andrea Brüggemann, Tom A Goetze, Markus Rapedius, Claudia Haarmann

J Lab Autom· December 2016

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Structural model of FeoB, the iron transporter from Pseudomonas aeruginosa, predicts a cysteine lined, GTP-gated pore.
Saeed Seyedmohammad, Natalia Alveal Fuentealba, Robert A J Marriott, Tom A Goetze, J Michael Edwardson

Biosci Rep· December 2016

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Identification of Drug-Drug Interactions In Vitro: A Case Study Evaluating the Effects of Sofosbuvir and Amiodarone on hiPSC-Derived Cardiomyocytes.
Daniel C Millard, Christopher J Strock, Coby B Carlson, Natsuyo Aoyama, Krisztina Juhasz, Tom A Goetze

Toxicol Sci· November 2016

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OEP40, a Regulated Glucose-permeable β-Barrel Solute Channel in the Chloroplast Outer Envelope Membrane.
Anke Harsman, Annette Schock, Birgit Hemmis, Vanessa Wahl, Ingrid Jeshen, Tom Alexander Goetze

J Biol Chem· August 2016

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Oep23 forms an ion channel in the chloroplast outer envelope.
Tom Alexander Goetze, Manali Patil, Ingrid Jeshen, Bettina Bölter, Sabine Grahl

BMC Plant Biol· February 2015

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Direct evidence for functional TRPV1/TRPA1 heteromers.
Michael J M Fischer, Dilshan Balasuriya, Pia Jeggle, Tom A Goetze, Peter A McNaughton

Pflugers Arch· December 2014

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Synthetic self-assembling clostridial chimera for modulation of sensory functions.
Enrico Ferrari, Chunjing Gu, Dhevahi Niranjan, Laura Restani, Christine Rasetti-Escargueil, Tom A Goetze

Bioconjug Chem· October 2013

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α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) and N-methyl-D-aspartate (NMDA) receptors adopt different subunit arrangements.
Dilshan Balasuriya, Tom A Goetze, Nelson P Barrera, Andrew P Stewart, Yuki Suzuki

J Biol Chem· July 2013

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Visualization of structural changes accompanying activation of N-methyl-D-aspartate (NMDA) receptors using fast-scan atomic force microscopy imaging.
Yuki Suzuki, Tom A Goetze, David Stroebel, Dilshan Balasuriya, Shige H Yoshimura

J Biol Chem· January 2013

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Characterization of Tic110, a channel-forming protein at the inner envelope membrane of chloroplasts, unveils a response to Ca(2+) and a stromal regulatory disulfide bridge.
Mónica Balsera, Tom A Goetze, Erika Kovács-Bogdán, Peter Schürmann, Richard Wagner

J Biol Chem· January 2009

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Molecular properties of Kcv, a virus encoded K+ channel.
Cinzia Pagliuca, Tom Alexander Goetze, Richard Wagner, Gerhard Thiel, Anna Moroni

Biochemistry· January 2007

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OEP37 is a new member of the chloroplast outer membrane ion channels.
Tom Alexander Goetze, Katrin Philippar, Irina Ilkavets, Jürgen Soll, Richard Wagner

J Biol Chem· June 2006

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