Publications by authors named "Tracy Hartman"

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In vitro effect of a non-immunosuppressive FKBP ligand, FK1706, on SARS-CoV-2 replication in combination with antivirals.
William E Fitzsimmons, Tracy L Hartman, Michelle Mendenhall, Catherine Z Chen

bioRxiv· February 2022

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The structure-activity profile of mercaptobenzamides' anti-HIV activity suggests that thermodynamics of metabolism is more important than binding affinity to the target.
Herman Nikolayevskiy, Marco Robello, Michael T Scerba, Evan H Pasternak, Mrinmoy Saha, Tracy L Hartman

Eur J Med Chem· September 2019

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Expanding the Antiviral Spectrum of 3-Fluoro-2-(phosphonomethoxy)propyl Acyclic Nucleoside Phosphonates: Diamyl Aspartate Amidate Prodrugs.
Min Luo, Elisabetta Groaz, Graciela Andrei, Robert Snoeck, Raj Kalkeri, Tracy Hartman

J Med Chem· July 2017

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Probing Mercaptobenzamides as HIV Inactivators via Nucleocapsid Protein 7.
Mrinmoy Saha, Michael T Scerba, Nathaniel I Shank, Tracy L Hartman, Caitlin A Buchholz

ChemMedChem· May 2017

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An analog of camptothecin inactive against Topoisomerase I is broadly neutralizing of HIV-1 through inhibition of Vif-dependent APOBEC3G degradation.
Ryan P Bennett, Ryan A Stewart, Priscilla A Hogan, Roger G Ptak, Marie K Mankowski, Tracy L Hartman

Antiviral Res· December 2016

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Synthesis and Antiviral Evaluation of Octadecyloxyethyl Benzyl 9-[(2-Phosphonomethoxy)ethyl]guanine (ODE-Bn-PMEG), a Potent Inhibitor of Transient HPV DNA Amplification.
James R Beadle, Nadejda Valiaeva, Guang Yang, Jei-Hwa Yu, Thomas R Broker, Tracy Hartman

J Med Chem· December 2016

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Systematic evaluation of methyl ester bioisosteres in the context of developing alkenyldiarylmethanes (ADAMs) as non-nucleoside reverse transcriptase inhibitors (NNRTIs) for anti-HIV-1 chemotherapy.
Ayako Hoshi, Takeshi Sakamoto, Jun Takayama, Meiyan Xuan, Mari Okazaki, Tracy L Hartman

Bioorg Med Chem· July 2016

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Anti-HSV activity of serpin antithrombin III.
Debra C Quenelle, Tracy L Hartman, Robert W Buckheit, Mark N Prichard, Ralf Geiben Lynn

Int Trends Immun· April 2014

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The Continuing Evolution of HIV-1 Therapy: Identification and Development of Novel Antiretroviral Agents Targeting Viral and Cellular Targets.
Tracy L Hartman, Robert W Buckheit

Mol Biol Int· August 2012

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Antiviral interactions of combinations of highly potent 2,4(1H,3H)-pyrimidinedione congeners and other anti-HIV agents.
Tracy L Hartman, Lu Yang, Robert W Buckheit

Antiviral Res· December 2011

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Was the pediatric emergency department or pediatric urgent care center setting more affected by the fall 2009 H1N1 influenza outbreak?
Gregory P Conners, Tracy Hartman, Milton A Fowler, Lisa L Schroeder, Thomas W Tryon

Clin Pediatr (Phila)· August 2011

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Development of hexadecyloxypropyl tenofovir (CMX157) for treatment of infection caused by wild-type and nucleoside/nucleotide-resistant HIV.
E Randall Lanier, Roger G Ptak, Bernhard M Lampert, Laurie Keilholz, Tracy Hartman

Antimicrob Agents Chemother· July 2010

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Inhibition of human immunodeficiency virus type 1 by triciribine involves the accessory protein nef.
Roger G Ptak, Brian G Gentry, Tracy L Hartman, Karen M Watson, M Clayton Osterling

Antimicrob Agents Chemother· April 2010

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Multivalent binding oligomers inhibit HIV Tat-TAR interaction critical for viral replication.
Deyun Wang, Jaclyn Iera, Heather Baker, Priscilla Hogan, Roger Ptak, Tracy Hartman

Bioorg Med Chem Lett· December 2009

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Crystallographic study of a novel subnanomolar inhibitor provides insight on the binding interactions of alkenyldiarylmethanes with human immunodeficiency virus-1 reverse transcriptase.
Matthew D Cullen, William C Ho, Joseph D Bauman, Kalyan Das, Eddy Arnold, Tracy L Hartman

J Med Chem· October 2009

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Synthesis of alkenyldiarylmethanes (ADAMs) containing benzo[d]isoxazole and oxazolidin-2-one rings, a new series of potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
Bo-Liang Deng, Yujie Zhao, Tracy L Hartman, Karen Watson, Robert W Buckheit

Eur J Med Chem· March 2009

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Investigation of the alkenyldiarylmethane non-nucleoside reverse transcriptase inhibitors as potential cAMP phosphodiesterase-4B2 inhibitors.
Matthew D Cullen, York-Fong Cheung, Miles D Houslay, Tracy L Hartman, Karen M Watson

Bioorg Med Chem Lett· February 2008

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Comparative evaluation of the inhibitory activities of a series of pyrimidinedione congeners that inhibit human immunodeficiency virus types 1 and 2.
Robert W Buckheit, Tracy L Hartman, Karen M Watson, Sun-Gan Chung, Eui-Hwan Cho

Antimicrob Agents Chemother· January 2008

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The structure-activity relationships of 2,4(1H,3H)-pyrimidinedione derivatives as potent HIV type 1 and type 2 inhibitors.
Robert W Buckheit, Tracy L Hartman, Karen M Watson, Ho Seok Kwon, Sun Hwan Lee

Antivir Chem Chemother· January 2008

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Inhibition of tubulin polymerization by select alkenyldiarylmethanes.
Matthew D Cullen, Taradas Sarkar, Ernest Hamel, Tracy L Hartman, Karen M Watson

Bioorg Med Chem Lett· January 2008

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Synthesis and biological evaluation of alkenyldiarylmethane HIV-1 non-nucleoside reverse transcriptase inhibitors that possess increased hydrolytic stability.
Matthew D Cullen, Bo-Liang Deng, Tracy L Hartman, Karen M Watson, Robert W Buckheit

J Med Chem· October 2007

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Synthesis and anti-HIV activity of new metabolically stable alkenyldiarylmethane non-nucleoside reverse transcriptase inhibitors incorporating N-methoxy imidoyl halide and 1,2,4-oxadiazole systems.
Takeshi Sakamoto, Matthew D Cullen, Tracy L Hartman, Karen M Watson, Robert W Buckheit

J Med Chem· July 2007

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Carrageenan/MIV-150 (PC-815), a combination microbicide.
José A Fernández-Romero, Mitchell Thorn, Stuart G Turville, Kanani Titchen, Kristin Sudol, Tracy L Hartman

Sex Transm Dis· January 2007

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Replacement of the metabolically labile methyl esters in the alkenyldiarylmethane series of non-nucleoside reverse transcriptase inhibitors with isoxazolone, isoxazole, oxazolone, or cyano substituents.
Bo-Liang Deng, Tracy L Hartman, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq

J Med Chem· August 2006

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Synthesis and anti-HIV activity of new alkenyldiarylmethane (ADAM) non-nucleoside reverse transcriptase inhibitors (NNRTIs) incorporating benzoxazolone and benzisoxazole rings.
Bo-Liang Deng, Matthew D Cullen, Zhigang Zhou, Tracy L Hartman, Robert W Buckheit

Bioorg Med Chem· April 2006

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