Publications by authors named "Trang Tieu"

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STX-478, a Mutant-Selective, Allosteric PI3Kα Inhibitor Spares Metabolic Dysfunction and Improves Therapeutic Response in PI3Kα-Mutant Xenografts.
Leonard Buckbinder, David J St Jean, Trang Tieu, Brendon Ladd, Brendan Hilbert

Cancer Discov· November 2023

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Aurora kinase inhibition sensitizes melanoma cells to T-cell-mediated cytotoxicity.
Simone Punt, Shruti Malu, Jodi A McKenzie, Soraya Zorro Manrique, Elien M Doorduijn, Trang N Tieu

Cancer Immunol Immunother· April 2021

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High-Throughput Quantitative Assay Technologies for Accelerating the Discovery and Optimization of Targeted Protein Degradation Therapeutics.
Jeffrey R Simard, Linda Lee, Ellen Vieux, Reina Improgo, Trang Tieu

SLAS Discov· April 2021

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Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation.
Yuting Sun, Madhavi Bandi, Timothy Lofton, Melinda Smith, Christopher A Bristow, Trang N Tieu

Cell Rep· January 2019

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The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy.
Jodi A McKenzie, Rina M Mbofung, Shruti Malu, Min Zhang, Emily Ashkin, Trang Tieu

J Natl Cancer Inst· July 2018

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The RNA-binding Protein MEX3B Mediates Resistance to Cancer Immunotherapy by Downregulating HLA-A Expression.
Lu Huang, Shruti Malu, Jodi A McKenzie, Miles C Andrews, Amjad H Talukder, Trang Tieu

Clin Cancer Res· July 2018

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HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes.
Rina M Mbofung, Jodi A McKenzie, Shruti Malu, Min Zhang, Weiyi Peng, Trang Tieu

Nat Commun· September 2017

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Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
Wylie S Palmer, Guillaume Poncet-Montange, Gang Liu, Alessia Petrocchi, Naphtali Reyna, Trang N Tieu

J Med Chem· February 2016

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Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.
Weiyi Peng, Jie Qing Chen, Chengwen Liu, Shruti Malu, Caitlin Creasy, Trang N Tieu

Cancer Discov· February 2016

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Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression.
Guocan Wang, Xin Lu, Prasenjit Dey, Pingna Deng, Chia Chin Wu, Trang N Tieu

Cancer Discov· January 2016

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The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNF-Mutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies.
Bhavatarini Vangamudi, Thomas A Paul, Parantu K Shah, Maria Kost-Alimova, Lisa Nottebaum, Trang N Tieu

Cancer Res· September 2015

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Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery.
Yanai Zhan, Maria Kost-Alimova, Xi Shi, Elisabetta Leo, Jennifer P Bardenhagen, Trang N Tieu

Epigenetics Chromatin· September 2015

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