Publications by authors named "Troy A Johnson"

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Discovery of IPN60090, a Clinical Stage Selective Glutaminase-1 (GLS-1) Inhibitor with Excellent Pharmacokinetic and Physicochemical Properties.
Michael J Soth, Kang Le, Maria Emilia Di Francesco, Matthew M Hamilton, Gang Liu, Sarah B Johnson, Troy A Johnson

J Med Chem· November 2020

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Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase.
Troy A Johnson, Matthew J Mcleod, Todd Holyoak

Biochemistry· January 2016

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A variable DNA recognition site organization establishes the LiaR-mediated cell envelope stress response of enterococci to daptomycin.
Milya Davlieva, Yiwen Shi, Paul G Leonard, Troy A Johnson, Michael R Zianni

Nucleic Acids Res· May 2015

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The Ω-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function.
Troy A Johnson, Todd Holyoak

Biochemistry· November 2012

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The pyruvate kinase model system, a cautionary tale for the use of osmolyte perturbations to support conformational equilibria in allostery.
Aron W Fenton, Troy A Johnson, Todd Holyoak

Protein Sci· September 2010

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Increasing the conformational entropy of the Omega-loop lid domain in phosphoenolpyruvate carboxykinase impairs catalysis and decreases catalytic fidelity .
Troy A Johnson, Todd Holyoak

Biochemistry· June 2010

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Active-site gating regulates substrate selectivity in a chymotrypsin-like serine protease the structure of haemophilus influenzae immunoglobulin A1 protease.
Troy A Johnson, Jiazhou Qiu, Andrew G Plaut, Todd Holyoak

J Mol Biol· June 2009

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