Publications by authors named "Uwe Jacob"

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Dual-targeting triplebody 33-16-123 (SPM-2) mediates effective redirected lysis of primary blasts from patients with a broad range of AML subtypes in combination with natural killer cells.
Todd A Braciak, Claudia C Roskopf, Sarah Wildenhain, Nadja C Fenn, Christian B Schiller, Uwe Jacob

Oncoimmunology· July 2018

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CD19-specific triplebody SPM-1 engages NK and γδ T cells for rapid and efficient lysis of malignant B-lymphoid cells.
Christian B Schiller, Todd A Braciak, Nadja C Fenn, Ursula J E Seidel, Claudia C Roskopf, Uwe Jacob

Oncotarget· December 2016

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NK cells from an AML patient have recovered in remission and reached comparable cytolytic activity to that of a healthy monozygotic twin mediated by the single-chain triplebody SPM-2.
Todd A Braciak, Sarah Wildenhain, Claudia C Roskopf, Ingo A Schubert, Georg H Fey, Uwe Jacob

J Transl Med· November 2013

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Optical pH detection within a protein crystal.
Klaus M Seemann, Reiner Kiefersauer, Uwe Jacob, Bernd Kuhn

J Phys Chem B· August 2012

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Demyelinating myelin oligodendrocyte glycoprotein-specific autoantibody response is focused on one dominant conformational epitope region in rodents.
Constanze Breithaupt, Beatrix Schäfer, Hannah Pellkofer, Robert Huber, Christopher Linington, Uwe Jacob

J Immunol· July 2008

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Amelioration of collagen-induced arthritis by human recombinant soluble FcgammaRIIb.
Sofia E Magnusson, Maria Andrén, Kajsa E Nilsson, Peter Sondermann, Uwe Jacob

Clin Immunol· May 2008

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High synovial expression of the inhibitory FcgammaRIIb in rheumatoid arthritis.
Sofia E Magnusson, Marianne Engström, Uwe Jacob, Ann-Kristin Ulfgren, Sandra Kleinau

Arthritis Res Ther· January 2008

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Open and closed structures of the UDP-glucose pyrophosphorylase from Leishmania major.
Thomas Steiner, Anne-Christin Lamerz, Petra Hess, Constanze Breithaupt, Stephan Krapp, Uwe Jacob

J Biol Chem· April 2007

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Crystal structure of the catalytic domain of DESC1, a new member of the type II transmembrane serine proteinase family.
Otto J P Kyrieleis, Robert Huber, Edgar Ong, Ryan Oehler, Mike Hunter, Uwe Jacob

FEBS J· April 2007

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The crystal structures of 3-TAPAP in complexes with the urokinase-type plasminogen activator and picrate.
Ewa Zesławska, Uwe Jacob, Jörg Stürzebecher, Barbara J Oleksyn

Bioorg Med Chem Lett· January 2006

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Structure and function of vertebrate CMP-sialic acid synthetases.
Anja K Münster-Kühnel, Joe Tiralongo, Stephan Krapp, Birgit Weinhold, Valentina Ritz-Sedlacek, Uwe Jacob

Glycobiology· October 2004

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Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents.
Andrea Schweinitz, Torsten Steinmetzer, Ingo J Banke, Matthias J E Arlt, Anne Stürzebecher, Uwe Jacob

J Biol Chem· August 2004

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The crystal structure of murine CMP-5-N-acetylneuraminic acid synthetase.
Stephan Krapp, Anja K Münster-Kühnel, Jens T Kaiser, Robert Huber, Joe Tiralongo, Uwe Jacob

J Mol Biol· December 2003

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Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein.
Constanze Breithaupt, Anna Schubart, Hilke Zander, Arne Skerra, Robert Huber, Uwe Jacob

Proc Natl Acad Sci U S A· August 2003

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Crystal structure of the carboxyltransferase subunit of the bacterial sodium ion pump glutaconyl-coenzyme A decarboxylase.
Kerstin S Wendt, Iris Schall, Robert Huber, Wolfgang Buckel, Uwe Jacob

EMBO J· July 2003

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Crystals of urokinase type plasminogen activator complexes reveal the binding mode of peptidomimetic inhibitors.
Ewa Zeslawska, Uwe Jacob, Andrea Schweinitz, Gary Coombs, Wolfram Bode

J Mol Biol· April 2003

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The 2.0A resolution structure of the catalytic portion of a cyanobacterial membrane-bound manganese superoxide dismutase.
Werner Atzenhofer, Günther Regelsberger, Uwe Jacob, Günter Peschek, Paul Furtmüller

J Mol Biol· August 2002

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