Publications by authors named "Wolfram Bode"

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Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin.
Mekdes Debela, Viktor Magdolen, Wolfgang Skala, Brigitta Elsässer, Eric L Schneider, Wolfram Bode

Sci Rep· July 2018

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Structural basis for the Zn2+ inhibition of the zymogen-like kallikrein-related peptidase 10.
Mekdes Debela, Viktor Magdolen, Wolfram Bode, Hans Brandstetter, Peter Goettig

Biol Chem· December 2016

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Structural basis for the sheddase function of human meprin β metalloproteinase at the plasma membrane.
Joan L Arolas, Claudia Broder, Tamara Jefferson, Tibisay Guevara, Erwin E Sterchi, Wolfram Bode

Proc Natl Acad Sci U S A· October 2012

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A standard orientation for metallopeptidases.
F Xavier Gomis-Rüth, Tiago O Botelho, Wolfram Bode

Biochim Biophys Acta· January 2012

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The dimer interface of the membrane type 1 matrix metalloproteinase hemopexin domain: crystal structure and biological functions.
Anna Tochowicz, Peter Goettig, Richard Evans, Robert Visse, Yasuyuki Shitomi, Wolfram Bode

J Biol Chem· March 2011

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Structural determinants of the ADAM inhibition by TIMP-3: crystal structure of the TACE-N-TIMP-3 complex.
Magdalena Wisniewska, Peter Goettig, Klaus Maskos, Edward Belouski, Dwight Winters, Wolfram Bode

J Mol Biol· September 2008

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Direct interaction between a human digestive protease and the mucoadhesive poly(acrylic acid).
Irantzu Pallarès, Daniel Fernández, Mireia Comellas-Bigler, Juan Fernández-Recio, Salvador Ventura, Wolfram Bode

Acta Crystallogr D Biol Crystallogr· July 2008

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Structure of a novel thrombin inhibitor with an uncharged D-amino acid as P1 residue.
Rainer Friedrich, Daniel Riester, Peter Göttig, Marcel Thürk, Andreas Schwienhorst, Wolfram Bode

Eur J Med Chem· June 2008

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Structures and specificity of the human kallikrein-related peptidases KLK 4, 5, 6, and 7.
Mekdes Debela, Nathalie Beaufort, Viktor Magdolen, Norman M Schechter, Charles S Craik, Wolfram Bode

Biol Chem· June 2008

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Structural basis of the zinc inhibition of human tissue kallikrein 5.
Mekdes Debela, Peter Goettig, Viktor Magdolen, Robert Huber, Norman M Schechter, Wolfram Bode

J Mol Biol· November 2007

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Macrocyclic statine-based inhibitors of BACE-1.
Alessandra Barazza, Marion Götz, Sergio A Cadamuro, Peter Goettig, Michael Willem, Wolfram Bode

Chembiochem· November 2007

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Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7.
Mekdes Debela, Petra Hess, Viktor Magdolen, Norman M Schechter, Thomas Steiner, Wolfram Bode

Proc Natl Acad Sci U S A· October 2007

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Structure and interaction modes of thrombin.
Wolfram Bode

Blood Cells Mol Dis· September 2007

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Crystal structures of MMP-9 complexes with five inhibitors: contribution of the flexible Arg424 side-chain to selectivity.
Anna Tochowicz, Klaus Maskos, Robert Huber, Ruth Oltenfreiter, Vincent Dive, Wolfram Bode

J Mol Biol· August 2007

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Crystal structure of the human carboxypeptidase N (kininase I) catalytic domain.
Cora Keil, Klaus Maskos, Manuel Than, J Todd Hoopes, Robert Huber, Wolfram Bode

J Mol Biol· February 2007

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Crystal structures of human tissue kallikrein 4: activity modulation by a specific zinc binding site.
Mekdes Debela, Viktor Magdolen, Valerie Grimminger, Christian Sommerhoff, Albrecht Messerschmidt, Wolfram Bode

J Mol Biol· October 2006

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Specificity profiling of seven human tissue kallikreins reveals individual subsite preferences.
Mekdes Debela, Viktor Magdolen, Norman Schechter, Martina Valachova, Friedrich Lottspeich, Wolfram Bode

J Biol Chem· September 2006

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Pore-forming scissors? A first structural glimpse of gamma-secretase.
Harald Steiner, Manuel Than, Wolfram Bode, Christian Haass

Trends Biochem Sci· September 2006

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Secondary amides of sulfonylated 3-amidinophenylalanine. New potent and selective inhibitors of matriptase.
Torsten Steinmetzer, Andrea Schweinitz, Anne Stürzebecher, Daniel Dönnecke, Kerstin Uhland, Wolfram Bode

J Med Chem· July 2006

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The structure of thrombin: a janus-headed proteinase.
Wolfram Bode

Semin Thromb Hemost· April 2006

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X-ray structures of free and leupeptin-complexed human alphaI-tryptase mutants: indication for an alpha-->beta-tryptase transition.
Kerstin B Rohr, Trevor Selwood, Ulf Marquardt, Robert Huber, Norman M Schechter, Wolfram Bode

J Mol Biol· March 2006

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Interplay of human tissue kallikrein 4 (hK4) with the plasminogen activation system: hK4 regulates the structure and functions of the urokinase-type plasminogen activator receptor (uPAR).
Nathalie Beaufort, Mekdes Debela, Sabine Creutzburg, Josef Kellermann, Wolfram Bode

Biol Chem· February 2006

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Novel fluorescent prothrombin analogs as probes of staphylocoagulase-prothrombin interactions.
Peter Panizzi, Rainer Friedrich, Pablo Fuentes-Prior, Heather K Kroh, Judy Briggs, Wolfram Bode

J Biol Chem· January 2006

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Rigidity and flexibility of dipeptidyl peptidase IV: crystal structures of and docking experiments with DPIV.
Michael Engel, Torsten Hoffmann, Susanne Manhart, Ulrich Heiser, Sylvie Chambre, Wolfram Bode

J Mol Biol· January 2006

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Structural basis of the resistance of an insect carboxypeptidase to plant protease inhibitors.
Alex Bayés, Mireia Comellas-Bigler, Monica Rodríguez de la Vega, Klaus Maskos, Wolfram Bode

Proc Natl Acad Sci U S A· November 2005

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