Publications by authors named "Varun Pathak"

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Human endothelial colony forming cells (ECFCs) require endothelial protein C receptor (EPCR) for cell cycle progression and angiogenic activity.
Sarah E J Chambers, Jasenka Guduric-Fuchs, Edoardo Pedrini, Pietro M Bertelli, Chutima Charoensuk, Varun Pathak

Angiogenesis· May 2025

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Atovaquone-induced activation of the PERK/eIF2α signaling axis mitigates metabolic radiosensitisation.
Jie Feng, Varun Pathak, Niall M Byrne, Sarah Chambers, Tongchuan Wang

Cell Commun Signal· April 2025

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Modulation of diabetes-related retinal pathophysiology by PTX3.
Varun Pathak, Pietro M Bertelli, Edoardo Pedrini, Kevin Harkin, Elisa Peixoto

Proc Natl Acad Sci U S A· October 2024

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A new gene signature for endothelial senescence identifies self-RNA sensing by retinoic acid-inducible gene I as a molecular facilitator of vascular aging.
Jasenka Guduric-Fuchs, Edoardo Pedrini, Pietro M Bertelli, Shannon McDonnell, Varun Pathak

Aging Cell· September 2024

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Ocular application of electrospun materials for drug delivery and cellular therapies.
Deepakkumar Mishra, Shilpkala Gade, Varun Pathak, Lalitkumar K Vora, Kiran Mcloughlin

Drug Discov Today· September 2023

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Human blood vessel organoids reveal a critical role for CTGF in maintaining microvascular integrity.
Sara G Romeo, Ilaria Secco, Edoardo Schneider, Christina M Reumiller, Celio X C Santos, Varun Pathak

Nat Commun· September 2023

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Retinal pigment epithelium extracellular vesicles are potent inducers of age-related macular degeneration disease phenotype in the outer retina.
Marzena Kurzawa-Akanbi, Phillip Whitfield, Florence Burté, Pietro Maria Bertelli, Varun Pathak

J Extracell Vesicles· December 2022

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Google Classroom as a Teaching Tool for Undergraduate Embryology.
Sunit Jadhav, Oshin Behl, Ananya Khurjekar, Varun Pathak, Akatya Sinha

Cureus· September 2022

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Long term high glucose exposure induces premature senescence in retinal endothelial cells.
Pietro Maria Bertelli, Edoardo Pedrini, David Hughes, Shannon McDonnell, Varun Pathak

Front Physiol· August 2022

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A Novel Online Dissection Course on Lower Limb Anatomy During the COVID-19 Pandemic.
Sunit V Jadhav, Vaishaly K Bharambe, Varun S Pathak, Ananya P Khurjekar, Raghav L Navandar

Cureus· March 2022

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The Long Pentraxin PTX3 as a New Biomarker and Pharmacological Target in Age-Related Macular Degeneration and Diabetic Retinopathy.
Matteo Stravalaci, Mariantonia Ferrara, Varun Pathak, Francesca Davi, Barbara Bottazzi

Front Pharmacol· January 2022

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Current concepts on endothelial stem cells definition, location, and markers.
Sarah E J Chambers, Varun Pathak, Edoardo Pedrini, Lou Soret, Nicolas Gendron

Stem Cells Transl Med· November 2021

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miR-130a activates the VEGFR2/STAT3/HIF1α axis to potentiate the vasoregenerative capacity of endothelial colony-forming cells in hypoxia.
Jasenka Guduric-Fuchs, Edoardo Pedrini, Judith Lechner, Sarah E J Chambers, Christina L O'Neill, Varun Pathak

Mol Ther Nucleic Acids· March 2021

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Vascular Regeneration for Ischemic Retinopathies: Hope from Cell Therapies.
Pietro Maria Bertelli, Edoardo Pedrini, Jasenka Guduric-Fuchs, Elisa Peixoto, Varun Pathak

Curr Eye Res· March 2020

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The effect of glenohumeral radial mismatch on different augmented total shoulder arthroplasty glenoid designs: a finite element analysis.
Vani J Sabesan, Diego J L Lima, James D Whaley, Varun Pathak, Liying Zhang

J Shoulder Elbow Surg· June 2019

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Biomechanical comparison of 2 augmented glenoid designs: an integrated kinematic finite element analysis.
Vani J Sabesan, Diego J L Lima, James D Whaley, Varun Pathak, Liying Zhang

J Shoulder Elbow Surg· June 2019

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Therapies for Type 1 Diabetes: Current Scenario and Future Perspectives.
Varun Pathak, Nupur Madhur Pathak, Christina L O'Neill, Jasenka Guduric-Fuchs, Reinhold J Medina

Clin Med Insights Endocrinol Diabetes· May 2019

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Cholecystokinin (CCK) and related adjunct peptide therapies for the treatment of obesity and type 2 diabetes.
Varun Pathak, Peter R Flatt, Nigel Irwin

Peptides· February 2018

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Beneficial metabolic effects of dietary epigallocatechin gallate alone and in combination with exendin-4 in high fat diabetic mice.
Nupur M Pathak, Paul J B Millar, Varun Pathak, Peter R Flatt, Victor A Gault

Mol Cell Endocrinol· January 2018

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Metabolic and neuroprotective effects of dapagliflozin and liraglutide in diabetic mice.
Paul Millar, Nupur Pathak, Vadivel Parthsarathy, Anthony J Bjourson, Maurice O'Kane, Varun Pathak

J Endocrinol· September 2017

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Erratum. A Novel CCK-8/GLP-1 Hybrid Peptide Exhibiting Prominent Insulinotropic, Glucose-Lowering, and Satiety Actions With Significant Therapeutic Potential in High-Fat-Fed Mice. Diabetes 2015;64:2996-3009.
Nigel Irwin, Varun Pathak, Peter R Flatt

Diabetes· April 2016

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Sequential induction of beta cell rest and stimulation using stable GIP inhibitor and GLP-1 mimetic peptides improves metabolic control in C57BL/KsJ db/db mice.
Varun Pathak, Srividya Vasu, Victor A Gault, Peter R Flatt, Nigel Irwin

Diabetologia· September 2015

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A Novel CCK-8/GLP-1 Hybrid Peptide Exhibiting Prominent Insulinotropic, Glucose-Lowering, and Satiety Actions With Significant Therapeutic Potential in High-Fat-Fed Mice.
Nigel Irwin, Varun Pathak, Peter R Flatt

Diabetes· August 2015

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A novel DPP IV-resistant C-terminally extended glucagon analogue exhibits weight-lowering and diabetes-protective effects in high-fat-fed mice mediated through glucagon and GLP-1 receptor activation.
Aisling M Lynch, Nupur Pathak, Varun Pathak, Finbarr P M O'Harte, Peter R Flatt

Diabetologia· September 2014

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Characterisation of the biological activity of xenin-25 degradation fragment peptides.
Christine M A Martin, Vadivel Parthsarathy, Varun Pathak, Victor A Gault, Peter R Flatt

J Endocrinol· May 2014

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