Publications by authors named "Wayne D Tilley"

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Reprogramming of Androgen Receptor Activity in Castration-resistant Prostate Cancer is Shaped by Truncated Variants.
Mitchell G Lawrence, Shivakumar Keerthikumar, Scott L Townley, Ashlee K Clark, Georgia B Cuffe, Wayne D Tilley

Eur Urol Focus· September 2025

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Are androgen receptor agonists a treatment option in bladder cancer?
Michael L De Ieso, Ahmed Faris Aldoghachi, Wayne D Tilley, Amy R Dwyer

J Steroid Biochem Mol Biol· January 2025

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A Deep Learning Approach for the Classification of Fibroglandular Breast Density in Histology Images of Human Breast Tissue.
Hanieh Heydarlou, Leigh J Hodson, Mohsen Dorraki, Theresa E Hickey, Wayne D Tilley

Cancers (Basel)· January 2025

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Author Correction: CDK9 inhibition constrains multiple oncogenic transcriptional and epigenetic pathways in prostate cancer.
Razia Rahman, Muhammed H Rahaman, Adrienne R Hanson, Nicholas Choo, Jianling Xie, Wayne D Tilley

Br J Cancer· November 2024

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CDK9 inhibition inhibits multiple oncogenic transcriptional and epigenetic pathways in prostate cancer.
Razia Rahman, Muhammed H Rahaman, Adrienne R Hanson, Nicholas Choo, Jianling Xie, Wayne D Tilley

Br J Cancer· October 2024

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ACSM1 and ACSM3 Regulate Fatty Acid Metabolism to Support Prostate Cancer Growth and Constrain Ferroptosis.
Raj K Shrestha, Zeyad D Nassar, Adrienne R Hanson, Richard Iggo, Scott L Townley, Wayne D Tilley

Cancer Res· July 2024

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Library size confounds biology in spatial transcriptomics data.
Dharmesh D Bhuva, Chin Wee Tan, Agus Salim, Claire Marceaux, Marie A Pickering, Wayne D Tilley

Genome Biol· April 2024

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Activity and safety of enobosarm, a novel, oral, selective androgen receptor modulator, in androgen receptor-positive, oestrogen receptor-positive, and HER2-negative advanced breast cancer (Study G200802): a randomised, open-label, multicentre, multinational, parallel design, phase 2 trial.
Carlo Palmieri, Hannah Linden, Stephen N Birrell, Sally Wheelwright, Elgene Lim, Wayne D Tilley

Lancet Oncol· March 2024

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The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer.
Leila Hosseinzadeh, Zoya Kikhtyak, Geraldine Laven-Law, Stephen M Pederson, Caroline G Puiu, Wayne D Tilley

Genome Biol· February 2024

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Selective inhibition of CDK9 in triple negative breast cancer.
Ebtihal H Mustafa, Geraldine Laven-Law, Zoya Kikhtyak, Van Nguyen, Simak Ali, Wayne D Tilley

Oncogene· January 2024

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Designing Fluorescent Nuclear Permeable Peptidomimetics to Target Proliferating Cell Nuclear Antigen.
Aimee J Horsfall, Theresa Chav, Jordan L Pederick, Zoya Kikhtyak, Bethiney C Vandborg, Wayne D Tilley

J Med Chem· August 2023

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Potent Stimulation of the Androgen Receptor Instigates a Viral Mimicry Response in Prostate Cancer.
Mohammadreza Alizadeh-Ghodsi, Katie L Owen, Scott L Townley, Damien Zanker, Samuel P G Rollin, Wayne D Tilley

Cancer Res Commun· July 2022

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Arming androgen receptors to oppose oncogenic estrogen receptor activity in breast cancer.
Theresa E Hickey, Amy R Dwyer, Wayne D Tilley

Br J Cancer· December 2021

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High-Throughput Imaging Assay for Drug Screening of 3D Prostate Cancer Organoids.
Nicholas Choo, Susanne Ramm, Jennii Luu, Jean M Winter, Luke A Selth, Wayne D Tilley

SLAS Discov· October 2021

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Lipidomic Profiling of Clinical Prostate Cancer Reveals Targetable Alterations in Membrane Lipid Composition.
Lisa M Butler, Chui Yan Mah, Jelle Machiels, Andrew D Vincent, Swati Irani, Wayne D Tilley

Cancer Res· October 2021

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A cell permeable bimane-constrained PCNA-interacting peptide.
Aimee J Horsfall, Beth A Vandborg, Zoya Kikhtyak, Denis B Scanlon, Wayne D Tilley

RSC Chem Biol· October 2021

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Jean Wilson and His Legacy, 50 Years and Counting.
Alexander P Kenigsberg, Wayne D Tilley, Ganesh V Raj

Urology· July 2021

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Androgen Receptor Signaling in Prostate Cancer Genomic Subtypes.
Lauren K Jillson, Gabriel A Yette, Teemu D Laajala, Wayne D Tilley, James C Costello

Cancers (Basel)· June 2021

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ELOVL5 Is a Critical and Targetable Fatty Acid Elongase in Prostate Cancer.
Margaret M Centenera, Julia S Scott, Jelle Machiels, Zeyad D Nassar, Deanna C Miller, Wayne D Tilley

Cancer Res· April 2021

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Corrigendum: Heparanase Promotes Syndecan-1 Expression to Mediate Fibrillar Collagen and Mammographic Density in Human Breast Tissue Cultured .
Xuan Huang, Gina Reye, Konstantin I Momot, Tony Blick, Thomas Lloyd, Wayne D Tilley

Front Cell Dev Biol· March 2021

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The androgen receptor is a tumor suppressor in estrogen receptor-positive breast cancer.
Theresa E Hickey, Luke A Selth, Kee Ming Chia, Geraldine Laven-Law, Heloisa H Milioli, Wayne D Tilley

Nat Med· February 2021

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Post-transcriptional Gene Regulation by MicroRNA-194 Promotes Neuroendocrine Transdifferentiation in Prostate Cancer.
Rayzel C Fernandes, John Toubia, Scott Townley, Adrienne R Hanson, B Kate Dredge, Wayne D Tilley

Cell Rep· January 2021

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MDM2 inhibition in combination with endocrine therapy and CDK4/6 inhibition for the treatment of ER-positive breast cancer.
Neil Portman, Heloisa H Milioli, Sarah Alexandrou, Rhiannon Coulson, Aliza Yong, Wayne D Tilley

Breast Cancer Res· August 2020

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Heparanase Promotes Syndecan-1 Expression to Mediate Fibrillar Collagen and Mammographic Density in Human Breast Tissue Cultured .
Xuan Huang, Gina Reye, Konstantin I Momot, Tony Blick, Thomas Lloyd, Wayne D Tilley

Front Cell Dev Biol· July 2020

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Endonuclease FEN1 Coregulates ERα Activity and Provides a Novel Drug Interface in Tamoxifen-Resistant Breast Cancer.
Koen D Flach, Manikandan Periyasamy, Ajit Jadhav, Dorjbal Dorjsuren, Joseph C Siefert, Wayne D Tilley

Cancer Res· May 2020

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