Publications by authors named "Wayne Guida"

Claim this Profile
D
Discovery of Clonixeril as a Sub-Femtomolar Modulator of the Human STING Receptor.
Robert P Sparks, William Lawless, Anna Kharitonova, Rainer Metcalf, Jamie Nunziata, Wayne C Guida

ACS Cent Sci· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Chemical synthesis, in vitro testing, and in silico Nampt-based molecular docking of novel aniline aromatic ring-substituted 2-aminothiazole analogs.
Ali A Husain, Ravikumar Manickam, Jonah Gordon, Sandhya Santhana, Katarzyna Mizgalska, Wayne C Guida

Can J Physiol Pharmacol· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Helical sulfonyl-γ-AApeptides modulating Aβ oligomerization and cytotoxicity by recognizing Aβ helix.
Heng Liu, Yunpeng Cui, Xue Zhao, Lulu Wei, Xudong Wang, Wayne Guida

Proc Natl Acad Sci U S A· February 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Correction: A small-molecule competitive inhibitor of phosphatidic acid binding by the AAA+ protein NSF/Sec18 blocks the SNARE-priming stage of vacuole fusion.
Robert P Sparks, Andres S Arango, Matthew L Starr, Zachary L Aboff, Logan R Hurst, Wayne C Guida

J Biol Chem· November 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cardioprotective Effects of 1-(3,6-Dibromo-carbazol-9-yl)-3-Phenylamino-Propan-2-Ol in Diabetic Hearts via Nicotinamide Phosphoribosyltransferase Activation.
Jared Tur, Sachin L Badole, Ravikumar Manickam, Kalyan C Chapalamadugu, Wanling Xuan, Wayne Guida

J Pharmacol Exp Ther· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Bioactivity improvement via display of the hydrophobic core of HYD1 in a cyclic β-hairpin-like scaffold, MTI-101.
Priyesh Jain, David B Badger, Yi Liang, Anthony W Gebhard, Daniel Santiago, Wayne C Guida

Pept Sci (Hoboken)· May 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The p.E152K-STIM1 mutation deregulates Ca signaling contributing to chronic pancreatitis.
Miguel Burgos, Reginald Philippe, Fabrice Antigny, Paul Buscaglia, Emmanuelle Masson, Wayne Guida

J Cell Sci· February 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An Allosteric Binding Site on Sortilin Regulates the Trafficking of VLDL, PCSK9, and LDLR in Hepatocytes.
Robert P Sparks, Andres S Arango, Jermaine L Jenkins, Wayne C Guida, Emad Tajkhorshid

Biochemistry· November 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A small-molecule competitive inhibitor of phosphatidic acid binding by the AAA+ protein NSF/Sec18 blocks the SNARE-priming stage of vacuole fusion.
Robert P Sparks, Andres S Arango, Matthew L Starr, Zachary L Aboff, Logan R Hurst, Wayne C Guida

J Biol Chem· November 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A specific small-molecule inhibitor of protein kinase CδI activity improves metabolic dysfunction in human adipocytes from obese individuals.
Robert Sparks, Ashley Lui, Deena Bader, Rekha Patel, Michel Murr, Wayne Guida

J Biol Chem· October 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Ligand-mediated protein degradation reveals functional conservation among sequence variants of the CUL4-type E3 ligase substrate receptor cereblon.
Afua A Akuffo, Aileen Y Alontaga, Rainer Metcalf, Matthew S Beatty, Andreas Becker, Wayne Guida

J Biol Chem· April 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mechanistic Studies of 1-Deoxy-D-Xylulose-5-Phosphate Synthase from .
Sumit Handa, Daniel R Dempsey, Divya Ramamoorthy, Nanci Cook, Wayne C Guida

Biochem Mol Biol J· January 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Molecular Dynamics Simulations of Membrane-Bound STIM1 to Investigate Conformational Changes during STIM1 Activation upon Calcium Release.
Sreya Mukherjee, Aleksandra Karolak, Marjolaine Debant, Paul Buscaglia, Yves Renaudineau, Wayne C Guida

J Chem Inf Model· February 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Phosphatidylinositol (3,4,5)-trisphosphate binds to sortilin and competes with neurotensin: Implications for very low density lipoprotein binding.
Robert P Sparks, Jermaine L Jenkins, Gregory E Miner, Yan Wang, Wayne C Guida

Biochem Biophys Res Commun· October 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Sortilin facilitates VLDL-B100 secretion by insulin sensitive McArdle RH7777 cells.
Robert P Sparks, Wayne C Guida, Mark P Sowden, Jermaine L Jenkins, Matthew L Starr

Biochem Biophys Res Commun· September 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cupriphilic compounds to aid in proteasome inhibition.
Sreya Mukherjee, Robert Sparks, Rainer Metcalf, Wesley Brooks, Kenyon Daniel, Wayne C Guida

Bioorg Med Chem Lett· August 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
Î
β-Strand mimics based on tetrahydropyridazinedione (tpd) peptide stitching.
Chang Won Kang, Matthew P Sarnowski, Sujeewa Ranatunga, Lukasz Wojtas, Rainer S Metcalf, Wayne C Guida

Chem Commun (Camb)· November 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A computational design approach for virtual screening of peptide interactions across K(+) channel families.
Craig A Doupnik, Katherine C Parra, Wayne C Guida

Comput Struct Biotechnol J· February 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Orally bioavailable 6-chloro-7-methoxy-4(1H)-quinolones efficacious against multiple stages of Plasmodium.
R Matthew Cross, David L Flanigan, Andrii Monastyrskyi, Alexis N LaCrue, Fabián E Sáenz, Wayne C Guida

J Med Chem· November 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
In silico characterization of an atypical MAPK phosphatase of Plasmodium falciparum as a suitable target for drug discovery.
Christopher O Campbell, Daniel N Santiago, Wayne C Guida, Roman Manetsch, John H Adams

Chem Biol Drug Des· August 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Production of recombinant 1-deoxy-d-xylulose-5-phosphate synthase from Plasmodium vivax in Escherichia coli.
Sumit Handa, Divya Ramamoorthy, Tyler J Spradling, Wayne C Guida, John H Adams

FEBS Open Bio· June 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Development of new -Arylbenzamides as STAT3 Dimerization Inhibitors.
Murali K Urlam, Roberta Pireddu, Yiyu Ge, Xiaolei Zhang, Ying Sun, Wayne C Guida

Medchemcomm· June 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Oxadiazole-isopropylamides as potent and noncovalent proteasome inhibitors.
Sevil Ozcan, Aslamuzzaman Kazi, Frank Marsilio, Bin Fang, Wayne C Guida

J Med Chem· May 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of a new binding site in E. coli FabH using Molecular dynamics simulations: validation by computational alanine mutagenesis and docking studies.
Divya Ramamoorthy, Edward Turos, Wayne C Guida

J Chem Inf Model· May 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A novel inhibitor of STAT3 homodimerization selectively suppresses STAT3 activity and malignant transformation.
Xiaolei Zhang, Ying Sun, Roberta Pireddu, Hua Yang, Murali K Urlam, Wayne C Guida

Cancer Res· March 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis