Publications by authors named "William D Lees"

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The current landscape of adaptive immune receptor genomic and repertoire data: OGRDB and VDJbase.
William D Lees, Ayelet Peres, Vered Klein, Naama Amos, Uddalok Jana

Nucleic Acids Res· November 2025

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Ultra-long sequencing for contiguous haplotype resolution of the human immunoglobulin heavy-chain locus.
Mari B Gornitzka, Egil Røsjø, Uddalok Jana, Easton E Ford, Alan Tourancheau, William D Lees

Genome Res· October 2025

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The Adaptive Immune Receptor Repertoire Knowledge Commons: An invitation to the community.
Lindsay G Cowell, Scott Christley, Felix Breden, Kevin A Burns, Brian D Corrie, William D Lees

Cell Syst· September 2025

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Characterization of extensive diversity in immunoglobulin light chain variable germline genes across biomedically important mouse strains.
Justin T Kos, Yana Safonova, Kaitlyn Shields, Catherine A Silver, William D Lees

Immunohorizons· July 2025

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Resolving haplotype variation and complex genetic architecture in the human immunoglobulin kappa chain locus in individuals of diverse ancestry.
Eric Engelbrecht, Oscar L Rodriguez, Kaitlyn Shields, Steven Schultze, David Tieri, William D Lees

Genes Immun· August 2024

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Digger: directed annotation of immunoglobulin and T cell receptor V, D, and J gene sequences and assemblies.
William D Lees, Swati Saha, Gur Yaari, Corey T Watson

Bioinformatics· March 2024

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AIRR-C IG Reference Sets: curated sets of immunoglobulin heavy and light chain germline genes.
Andrew M Collins, Mats Ohlin, Martin Corcoran, James M Heather, Duncan Ralph, William D Lees

Front Immunol· February 2024

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IGHV allele similarity clustering improves genotype inference from adaptive immune receptor repertoire sequencing data.
Ayelet Peres, William D Lees, Oscar L Rodriguez, Noah Y Lee, Pazit Polak

Nucleic Acids Res· September 2023

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AIRR community curation and standardised representation for immunoglobulin and T cell receptor germline sets.
William D Lees, Scott Christley, Ayelet Peres, Justin T Kos, Brian Corrie

Immunoinformatics (Amst)· June 2023

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An entropic safety catch controls hepatitis C virus entry and antibody resistance.
Lenka Stejskal, Mphatso D Kalemera, Charlotte B Lewis, Machaela Palor, Lucas Walker, William D Lees

Elife· July 2022

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Adaptive Immune Receptor Repertoire (AIRR) Community Guide to TR and IG Gene Annotation.
Lmar Babrak, Susanna Marquez, Christian E Busse, William D Lees, Enkelejda Miho

Methods Mol Biol· May 2022

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Adaptive Immune Receptor Repertoire (AIRR) Community Guide to Repertoire Analysis.
Susanna Marquez, Lmar Babrak, Victor Greiff, Kenneth B Hoehn, William D Lees

Methods Mol Biol· May 2022

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Commentary on Population matched (pm) germline allelic variants of immunoglobulin (IG) loci: relevance in infectious diseases and vaccination studies in human populations.
Andrew M Collins, Ayelet Peres, Martin M Corcoran, Corey T Watson, Gur Yaari, William D Lees

Genes Immun· December 2021

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Diversity in immunogenomics: the value and the challenge.
Kerui Peng, Yana Safonova, Mikhail Shugay, Alice B Popejoy, Oscar L Rodriguez, William D Lees

Nat Methods· June 2021

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Inferred Allelic Variants of Immunoglobulin Receptor Genes: A System for Their Evaluation, Documentation, and Naming.
Mats Ohlin, Cathrine Scheepers, Martin Corcoran, William D Lees, Christian E Busse

Front Immunol· September 2020

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Flexibility and intrinsic disorder are conserved features of hepatitis C virus E2 glycoprotein.
Lenka Stejskal, William D Lees, David S Moss, Machaela Palor, Richard J Bingham

PLoS Comput Biol· February 2020

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Studying Antibody Repertoires with Next-Generation Sequencing.
William D Lees, Adrian J Shepherd

Methods Mol Biol· January 2018

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Investigating Substitutions in Antibody-Antigen Complexes Using Molecular Dynamics: A Case Study with Broad-spectrum, Influenza A Antibodies.
William D Lees, Lenka Stejskal, David S Moss, Adrian J Shepherd

Front Immunol· February 2017

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Utilities for High-Throughput Analysis of B-Cell Clonal Lineages.
William D Lees, Adrian J Shepherd

J Immunol Res· August 2016

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N-linked glycans on influenza A H3N2 hemagglutinin constrain binding of host antibodies, but shielding is limited.
Kevin Pentiah, William D Lees, David S Moss, Adrian J Shepherd

Glycobiology· January 2015

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Evolution in the influenza A H3 stalk - a challenge for broad-spectrum vaccines?
William D Lees, David S Moss, Adrian J Shepherd

J Gen Virol· February 2014

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Analysis of antigenically important residues in human influenza A virus in terms of B-cell epitopes.
William D Lees, David S Moss, Adrian J Shepherd

J Virol· September 2011

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A computational analysis of the antigenic properties of haemagglutinin in influenza A H3N2.
William D Lees, David S Moss, Adrian J Shepherd

Bioinformatics· June 2010

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