Publications by authors named "William Gillette"

Claim this Profile
B
Biophysical and structural analysis of KRAS switch-II pocket inhibitors reveals allele-specific binding constraints.
Patrick Alexander, Albert H Chan, Dana Rabara, Monalisa Swain, Erik K Larsen, William K Gillette

J Biol Chem· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
NMR H, C, and N resonance assignments of the oncogenic Q61R variant of human NRAS in the active, GTP-bound conformation.
Alok K Sharma, Marco Tonelli, Marcin Dyba, William K Gillette, Dominic Esposito

Biomol NMR Assign· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine.
Anna E Maciag, Yue Yang, Alok K Sharma, David M Turner, Caroline J DeHart, William Gillette

Proc Natl Acad Sci U S A· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Improvements in large-scale production of tobacco etch virus protease.
Simon Messing, Kirsten Barnhart, Matthew Drew, Natalie Granato-Guerrero, Carissa Grose, William Gillette

Protein Expr Purif· April 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Improved production of class I phosphatidylinositol 4,5-bisphosphate 3-kinase.
Simon Messing, Stephanie R T Widmeyer, John-Paul Denson, Jennifer Mehalko, Vanessa E Wall, William Gillette

Protein Expr Purif· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structural insights into isoform-specific RAS-PI3Kα interactions and the role of RAS in PI3Kα activation.
Daniel Czyzyk, Wupeng Yan, Simon Messing, William Gillette, Takashi Tsuji

Nat Commun· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Beyond KRAS(G12C): Biochemical and Computational Characterization of Sotorasib and Adagrasib Binding Specificity and the Critical Role of H95 and Y96.
Randa Mahran, Jonas N Kapp, Salla Valtonen, Allison Champagne, Jinying Ning, William Gillette

ACS Chem Biol· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Natural Product Graveoline Modulates Kirsten Rat Sarcoma Viral Oncogene Homologue (KRAS) Membrane Association: Insights from Advanced Spectroscopic Studies.
Gabriel Cornilescu, Lakshman Bindu, Louise Sternicki, Fa-An Chao, William K Gillette

ACS Pharmacol Transl Sci· July 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Producing recombinant proteins in Vibrio natriegens.
Matthew Smith, José Sánchez Hernández, Simon Messing, Nitya Ramakrishnan, Brianna Higgins, William Gillette

Microb Cell Fact· July 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Adapting recombinant bacterial alkaline phosphatase for nucleotide exchange of small GTPases.
Peter H Frank, Min Hong, Brianna Higgins, Shelley Perkins, Troy Taylor, William Gillette

Protein Expr Purif· June 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Production of Isotopically Labeled KRAS4b.
Troy Taylor, William Gillette

Methods Mol Biol· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Author Correction: Membrane lipids drive formation of KRAS4b-RAF1 RBDCRD nanoclusters on the membrane.
Rebika Shrestha, Timothy S Carpenter, Que N Van, Constance Agamasu, Marco Tonelli, William K Gillette

Commun Biol· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Membrane lipids drive formation of KRAS4b-RAF1 RBDCRD nanoclusters on the membrane.
Rebika Shrestha, Timothy S Carpenter, Que N Van, Constance Agamasu, Marco Tonelli, William K Gillette

Commun Biol· February 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A humanized nanobody phage display library yields potent binders of SARS CoV-2 spike.
Ying Fu, Juliana da Fonseca Rezende E Mello, Bryan D Fleming, Alex Renn, Catherine Z Chen, William Gillette

PLoS One· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Thermal Shift Assay for Small GTPase Stability Screening: Evaluation and Suitability.
Kari Kopra, Salla Valtonen, Randa Mahran, Jonas N Kapp, Nazia Hassan, William Gillette

Int J Mol Sci· June 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
NMR H, C, N backbone resonance assignments of the T35S and oncogenic T35S/Q61L mutants of human KRAS4b in the active, GppNHp-bound conformation.
Alok K Sharma, Marcin Dyba, Marco Tonelli, Brian Smith, William K Gillette

Biomol NMR Assign· April 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A humanized nanobody phage display library yields potent binders of SARS CoV-2 spike.
Ying Fu, Juliana da Fonseca Rezende E Mello, Bryan D Fleming, Alex Renn, Catherine Z Chen, William Gillette

bioRxiv· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Insights into the Cross Talk between Effector and Allosteric Lobes of KRAS from Methyl Conformational Dynamics.
Fa-An Chao, Srisathiyanarayanan Dharmaiah, Troy Taylor, Simon Messing, William Gillette

J Am Chem Soc· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Undiagnosed SARS-CoV-2 seropositivity during the first 6 months of the COVID-19 pandemic in the United States.
Heather Kalish, Carleen Klumpp-Thomas, Sally Hunsberger, Holly Ann Baus, Michael P Fay, William Gillette

Sci Transl Med· July 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Production and Membrane Binding of N-Terminally Acetylated, C-Terminally Farnesylated and Carboxymethylated KRAS4b.
Simon Messing, Constance Agamasu, Matt Drew, Caroline J DeHart, Andrew G Stephen, William K Gillette

Methods Mol Biol· June 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Improved production of SARS-CoV-2 spike receptor-binding domain (RBD) for serology assays.
Jennifer Mehalko, Matthew Drew, Kelly Snead, John-Paul Denson, Vanessa Wall, William Gillette

Protein Expr Purif· March 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Standardization of ELISA protocols for serosurveys of the SARS-CoV-2 pandemic using clinical and at-home blood sampling.
Carleen Klumpp-Thomas, Heather Kalish, Matthew Drew, Sally Hunsberger, Kelly Snead, William Gillette

Nat Commun· January 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mapping a Pandemic: SARS-CoV-2 Seropositivity in the United States.
Heather Kalish, Carleen Klumpp-Thomas, Sally Hunsberger, Holly Ann Baus, Michael P Fay, William Gillette

medRxiv· January 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Improved production of SARS-CoV-2 spike receptor-binding domain (RBD) for serology assays.
Jennifer Mehalko, Matthew Drew, Kelly Snead, John-Paul Denson, Vanessa Wall, William Gillette

bioRxiv· November 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Uncovering a membrane-distal conformation of KRAS available to recruit RAF to the plasma membrane.
Que N Van, Cesar A López, Marco Tonelli, Troy Taylor, Ben Niu, William K Gillette

Proc Natl Acad Sci U S A· September 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis