Publications by authors named "William Hewitt"

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Interdisciplinary Quality Improvement Project Increases Vitamin D Supplementation in Infants.
Noah P Diminick, Jamie M Fey, Jonathan Bourque, Patricia Crosby, Leah Fox, William Hewitt

Pediatrics· September 2022

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A Case of Fastidious Mycobacterium chelonae-Causative Cellulitis: Clinical Manifestations of a Rare Bacterial Infection.
Grant E Gregory, Hannah M Gregory, Mo Zaman, William D Hewitt

Cureus· June 2022

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Clinical Effects of the Self-administered Subcutaneous Complement Inhibitor Zilucoplan in Patients With Moderate to Severe Generalized Myasthenia Gravis: Results of a Phase 2 Randomized, Double-Blind, Placebo-Controlled, Multicenter Clinical Trial.
James F Howard, Richard J Nowak, Gil I Wolfe, Miriam L Freimer, Tuan H Vu, William Hewitt

JAMA Neurol· May 2020

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Evidence for ligandable sites in structured RNA throughout the Protein Data Bank.
William M Hewitt, David R Calabrese, John S Schneekloth

Bioorg Med Chem· June 2019

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Lipophilic Permeability Efficiency Reconciles the Opposing Roles of Lipophilicity in Membrane Permeability and Aqueous Solubility.
Matthew R Naylor, Andrew M Ly, Mason J Handford, Daniel P Ramos, Cameron R Pye, William M Hewitt

J Med Chem· December 2018

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Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex.
David R Calabrese, Xiang Chen, Elena C Leon, Snehal M Gaikwad, Zaw Phyo, William M Hewitt

Nat Commun· October 2018

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Characterization of clinically used oral antiseptics as quadruplex-binding ligands.
David R Calabrese, Katherine Zlotkowski, Stephanie Alden, William M Hewitt, Colleen M Connelly

Nucleic Acids Res· April 2018

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A Small-Molecule Microarray Approach for the Identification of E2 Enzyme Inhibitors in Ubiquitin-Like Conjugation Pathways.
Katherine Zlotkowski, William M Hewitt, Ranu S Sinniah, Joseph E Tropea, Danielle Needle

SLAS Discov· July 2017

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Macrophilone A: Structure Elucidation, Total Synthesis, and Functional Evaluation of a Biologically Active Iminoquinone from the Marine Hydroid Macrorhynchia philippina.
Katherine Zlotkowski, William M Hewitt, Pengcheng Yan, Heidi R Bokesch, Megan L Peach

Org Lett· April 2017

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Nonclassical Size Dependence of Permeation Defines Bounds for Passive Adsorption of Large Drug Molecules.
Cameron R Pye, William M Hewitt, Joshua Schwochert, Terra D Haddad, Chad E Townsend

J Med Chem· March 2017

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Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9.
William M Hewitt, George T Lountos, Katherine Zlotkowski, Samuel D Dahlhauser, Lindsey B Saunders

Angew Chem Int Ed Engl· May 2016

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Probing the Physicochemical Boundaries of Cell Permeability and Oral Bioavailability in Lipophilic Macrocycles Inspired by Natural Products.
Andrew T Bockus, Katrina W Lexa, Cameron R Pye, Amit S Kalgutkar, Jarret W Gardner, William M Hewitt

J Med Chem· June 2015

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Cell-permeable cyclic peptides from synthetic libraries inspired by natural products.
William M Hewitt, Siegfried S F Leung, Cameron R Pye, Alexandra R Ponkey, Maria Bednarek

J Am Chem Soc· January 2015

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Manipulation of intraparticle charge delocalization by selective complexation of transition-metal ions with histidine moieties.
Xiongwu Kang, Xiang Li, William M Hewitt, Nathaniel B Zuckerman, Joseph P Konopelski

Anal Chem· February 2012

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