Publications by authors named "Xavier Codony"

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Generation and phenotypic characterization of a sigma-1 receptor knockout rat.
Miguel Á Huerta, Xavier Codony, M Carmen Ruiz-Cantero, Mónica Porras, Miguel Á Tejada

Life Sci· November 2025

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Bispecific sigma-1 receptor antagonism and mu-opioid receptor partial agonism: WLB-73502, an analgesic with improved efficacy and safety profile compared to strong opioids.
Alba Vidal-Torres, Begoña Fernández-Pastor, Mónica García, Eva Ayet, Anna Cabot, Xavier Codony

Acta Pharm Sin B· January 2023

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Repeated Sigma-1 Receptor Antagonist MR309 Administration Modulates Central Neuropathic Pain Development After Spinal Cord Injury in Mice.
Sílvia Castany, Xavier Codony, Daniel Zamanillo, Manuel Merlos, Enrique Verdú

Front Pharmacol· March 2019

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Administration of a co-crystal of tramadol and celecoxib in a 1:1 molecular ratio produces synergistic antinociceptive effects in a postoperative pain model in rats.
Manuel Merlos, Enrique Portillo-Salido, Alex Brenchat, Bertrand Aubel, Jordi Buxens, Xavier Codony

Eur J Pharmacol· August 2018

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Sigma-1 receptor antagonism as opioid adjuvant strategy: enhancement of opioid antinociception without increasing adverse effects.
Alba Vidal-Torres, Beatriz de la Puente, Maria Rocasalbas, Clara Touriño, Simona Andreea Bura, Xavier Codony

Eur J Pharmacol· July 2013

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5-HT6 receptor signal transduction second messenger systems.
Xavier Codony, Javier Burgueño, Maria Javier Ramírez, José Miguel Vela

Int Rev Neurobiol· September 2011

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E-6801, a 5-HT6 receptor agonist, improves recognition memory by combined modulation of cholinergic and glutamatergic neurotransmission in the rat.
Ian Kendall, Helge A Slotten, Xavier Codony, Javier Burgueño, Peter J Pauwels

Psychopharmacology (Berl)· February 2011

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Pharmacological activation of 5-HT7 receptors reduces nerve injury-induced mechanical and thermal hypersensitivity.
Alex Brenchat, Xavier Nadal, Luz Romero, Sergio Ovalle, Asunción Muro, Xavier Codony

Pain· June 2010

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Discovery of 5-HT6 receptor ligands based on virtual HTS.
Stefan Tasler, Jürgen Kraus, Andreas Wuzik, Oliver Müller, Andrea Aschenbrenner, Xavier Codony

Bioorg Med Chem Lett· November 2007

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Chronic 5-HT6 receptor modulation by E-6837 induces hypophagia and sustained weight loss in diet-induced obese rats.
Angels Fisas, Xavier Codony, Gonzalo Romero, Alberto Dordal, Jesus Giraldo

Br J Pharmacol· August 2006

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Efficacy of selective 5-HT6 receptor ligands determined by monitoring 5-HT6 receptor-mediated cAMP signaling pathways.
Gonzalo Romero, Elisabeth Sánchez, Marta Pujol, Pilar Pérez, Xavier Codony

Br J Pharmacol· August 2006

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Medicinal chemistry strategies to 5-HT(6) receptor ligands as potential cognitive enhancers and antiobesity agents.
Jörg Holenz, Petrus J Pauwels, José Luis Díaz, Ramon Mercè, Xavier Codony

Drug Discov Today· April 2006

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Medicinal chemistry driven approaches toward novel and selective serotonin 5-HT6 receptor ligands.
Jörg Holenz, Ramon Mercè, José Luis Díaz, Xavier Guitart, Xavier Codony

J Med Chem· March 2005

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Sigma receptors: biology and therapeutic potential.
Xavier Guitart, Xavier Codony, Xavier Monroy

Psychopharmacology (Berl)· July 2004

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Generation and phenotypic analysis of sigma receptor type I (sigma 1) knockout mice.
Francina Langa, Xavier Codony, Victoria Tovar, Alfonso Lavado, Estela Giménez

Eur J Neurosci· October 2003

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