Publications by authors named "YoonAe Ko"

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Characterization of a new selective glucocorticoid receptor modulator with anorexigenic activity.
Junekyoung Lee, Yeonghun Song, Young A Kim, Intae Kim, Jooseon Cha, Yoonae Ko

Sci Rep· April 2024

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Targeting HMG-CoA synthase 2 suppresses tamoxifen-resistant breast cancer growth by augmenting mitochondrial oxidative stress-mediated cell death.
Sewon Hwang, Soojun Park, Jee Hyun Kim, Sang-Beom Bang, Hyeon-Ji Kim, Yoonae Ko

Life Sci· September 2023

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Pharmacological perturbation of thiamine metabolism sensitizes Pseudomonas aeruginosa to multiple antibacterial agents.
Hyung Jun Kim, Yingying Li, Michael Zimmermann, Yunmi Lee, Hui Wen Lim, Yoonae Ko

Cell Chem Biol· August 2022

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The ThiL enzyme is a valid antibacterial target essential for both thiamine biosynthesis and salvage pathways in .
Hyung Jun Kim, Hyunjung Lee, Yunmi Lee, Inhee Choi, Yoonae Ko

J Biol Chem· July 2020

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Kinome-Wide RNA Interference Screening Identifies Mitogen-Activated Protein Kinases and Phosphatidylinositol Metabolism as Key Factors for Rabies Virus Infection.
Benoit Besson, Seonhee Kim, Taehee Kim, Yoonae Ko, Sangchul Lee

mSphere· May 2019

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High-throughput drug screening using the Ebola virus transcription- and replication-competent virus-like particle system.
Nakyung Lee, David Shum, Alexander König, Hichul Kim, Jinyeong Heo, Yoonae Ko

Antiviral Res· October 2018

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Identification of pyrrolo[3,2-c]pyridin-4-amine compounds as a new class of entry inhibitors against influenza viruses in vitro.
So Young Chang, Deu John M Cruz, Yoonae Ko, Ji-Young Min

Biochem Biophys Res Commun· September 2016

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Benzothiazepinecarboxamides: Novel hepatitis C virus inhibitors that interfere with viral entry and the generation of infectious virions.
Hee-Young Kim, Sunju Kong, Sangmi Oh, Jaewon Yang, Eunji Jo, Yoonae Ko

Antiviral Res· May 2016

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Serendipitous discovery of 2-((phenylsulfonyl)methyl)-thieno[3,2-d]pyrimidine derivatives as novel HIV-1 replication inhibitors.
Junwon Kim, Jeongjin Kwon, Doohyun Lee, Suyeon Jo, Dong-Sik Park, Yoonae Ko

Bioorg Med Chem Lett· December 2014

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Synthesis and evaluation of hexahydropyrimidines and diamines as novel hepatitis C virus inhibitors.
Jong Yeon Hwang, Hee-Young Kim, Suyeon Jo, Eunjung Park, Jihyun Choi, Sunju Kong, Yoonae Ko

Eur J Med Chem· September 2014

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Lead optimization of a novel series of imidazo[1,2-a]pyridine amides leading to a clinical candidate (Q203) as a multi- and extensively-drug-resistant anti-tuberculosis agent.
Sunhee Kang, Ryang Yeo Kim, Min Jung Seo, Saeyeon Lee, Young Mi Kim, Yoonae Ko

J Med Chem· June 2014

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Identification of a novel sulfonamide non-nucleoside reverse transcriptase inhibitor by a phenotypic HIV-1 full replication assay.
Tae-Hee Kim, Yoonae Ko, Thierry Christophe, Jonathan Cechetto, Junwon Kim

PLoS One· February 2014

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Anti-obesity phenotypic screening looking to increase OBR cell surface expression.
Tae-Hee Kim, Dong-Hwa Choi, Virginie Vauthier, Julie Dam, Xiaolan Li, YoonAe Ko

J Biomol Screen· January 2014

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Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis.
Kevin Pethe, Pablo Bifani, Jichan Jang, Sunhee Kang, Seijin Park, Yoonae Ko

Nat Med· September 2013

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Synthesis and biological evaluation of triazolothienopyrimidine derivatives as novel HIV-1 replication inhibitors.
Junwon Kim, Jeongjin Kwon, Doohyun Lee, Suyeon Jo, Dong-Sik Park, Yoonae Ko

Bioorg Med Chem Lett· January 2013

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Discovery of Phenylaminopyridine Derivatives as Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors.
Junwon Kim, Doohyun Lee, Changmin Park, Wonyoung So, Mina Jo, Sunju Kong, Yoonae Ko

ACS Med Chem Lett· August 2012

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A novel 3,4-dihydropyrimidin-2(1H)-one: HIV-1 replication inhibitors with improved metabolic stability.
Junwon Kim, Taedong Ok, Changmin Park, Wonyoung So, Mina Jo, Yoonae Ko

Bioorg Med Chem Lett· April 2012

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Identification of (beta-carboxyethyl)-rhodanine derivatives exhibiting peroxisome proliferator-activated receptor gamma activity.
Jiwon Choi, Yoonae Ko, Hui Sun Lee, Yun Sun Park, Young Yang

Eur J Med Chem· January 2010

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Cyanobacterial glucokinase complements the glucose sensing role of Arabidopsis thaliana hexokinase 1.
Jee-Youn Ryu, Seok-Won Jeong, Soo Youn Kim, Yoonae Ko, Sukjoon Yoon

Biochem Biophys Res Commun· September 2008

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