Publications by authors named "Jonathan Cechetto"

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Pharmacological perturbation of thiamine metabolism sensitizes Pseudomonas aeruginosa to multiple antibacterial agents.
Hyung Jun Kim, Yingying Li, Michael Zimmermann, Yunmi Lee, Hui Wen Lim, Jonathan Cechetto

Cell Chem Biol· August 2022

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Identification and characterization of a novel hepatitis B virus pregenomic RNA encapsidation inhibitor.
Eunji Jo, Dong-Kyun Ryu, Alexander König, Soonju Park, Yoojin Cho, Jonathan Cechetto

Antiviral Res· March 2020

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Serendipitous discovery of 2-((phenylsulfonyl)methyl)-thieno[3,2-d]pyrimidine derivatives as novel HIV-1 replication inhibitors.
Junwon Kim, Jeongjin Kwon, Doohyun Lee, Suyeon Jo, Dong-Sik Park, Jonathan Cechetto

Bioorg Med Chem Lett· December 2014

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Synthesis and evaluation of hexahydropyrimidines and diamines as novel hepatitis C virus inhibitors.
Jong Yeon Hwang, Hee-Young Kim, Suyeon Jo, Eunjung Park, Jihyun Choi, Jonathan Cechetto

Eur J Med Chem· September 2014

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Discovery of carbohybrid-based 2-aminopyrimidine analogues as a new class of rapid-acting antimalarial agents using image-based cytological profiling assay.
Sukjun Lee, Donghyun Lim, Eunyoung Lee, Nakyung Lee, Hong-Gun Lee, Jonathan Cechetto

J Med Chem· September 2014

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Encapsulation of Anti-Tuberculosis Drugs within Mesoporous Silica and Intracellular Antibacterial Activities.
Xin Xia, Kevin Pethe, Ryangyeo Kim, Lluis Ballell, David Barros, Jonathan Cechetto

Nanomaterials (Basel)· September 2014

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Identification of a novel sulfonamide non-nucleoside reverse transcriptase inhibitor by a phenotypic HIV-1 full replication assay.
Tae-Hee Kim, Yoonae Ko, Thierry Christophe, Jonathan Cechetto, Junwon Kim

PLoS One· February 2014

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Anti-obesity phenotypic screening looking to increase OBR cell surface expression.
Tae-Hee Kim, Dong-Hwa Choi, Virginie Vauthier, Julie Dam, Xiaolan Li, Jonathan Cechetto

J Biomol Screen· January 2014

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Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis.
Kevin Pethe, Pablo Bifani, Jichan Jang, Sunhee Kang, Seijin Park, Jonathan Cechetto

Nat Med· September 2013

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Identification of two HIV inhibitors that also inhibit human RNaseH2.
Junghwan Kim, Jaewan Yoon, MoonKyeong Ju, Yunmi Lee, Tae-Hee Kim, Jonathan Cechetto

Mol Cells· September 2013

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Synthesis and biological evaluation of triazolothienopyrimidine derivatives as novel HIV-1 replication inhibitors.
Junwon Kim, Jeongjin Kwon, Doohyun Lee, Suyeon Jo, Dong-Sik Park, Jonathan Cechetto

Bioorg Med Chem Lett· January 2013

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Discovery and characterization of a novel 7-aminopyrazolo[1,5-a]pyrimidine analog as a potent hepatitis C virus inhibitor.
Jong Yeon Hwang, Marc Peter Windisch, Suyeon Jo, Keumhyun Kim, Sunju Kong, Jonathan Cechetto

Bioorg Med Chem Lett· December 2012

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High content screening for compounds that induce early stages of human embryonic stem cell differentiation.
JooHyun Jee, HeeKyoung Jeon, DongYoun Hwang, Peter Sommer, Zewon Park, Jonathan Cechetto

Comb Chem High Throughput Screen· September 2012

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An image-based high-content screening assay for compounds targeting intracellular Leishmania donovani amastigotes in human macrophages.
Jair L Siqueira-Neto, Seunghyun Moon, Jiyeon Jang, Gyongseon Yang, Changbok Lee, Jonathan Cechetto

PLoS Negl Trop Dis· September 2012

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Discovery of Phenylaminopyridine Derivatives as Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors.
Junwon Kim, Doohyun Lee, Changmin Park, Wonyoung So, Mina Jo, Jonathan Cechetto

ACS Med Chem Lett· August 2012

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A novel 3,4-dihydropyrimidin-2(1H)-one: HIV-1 replication inhibitors with improved metabolic stability.
Junwon Kim, Taedong Ok, Changmin Park, Wonyoung So, Mina Jo, Jonathan Cechetto

Bioorg Med Chem Lett· April 2012

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Discovery of 3,4-dihydropyrimidin-2(1H)-ones with inhibitory activity against HIV-1 replication.
Junwon Kim, Changmin Park, Taedong Ok, Wonyoung So, Mina Jo, Jonathan Cechetto

Bioorg Med Chem Lett· March 2012

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High-content imaging of Mycobacterium tuberculosis-infected macrophages: an in vitro model for tuberculosis drug discovery.
Thierry Christophe, Fanny Ewann, Hee Kyoung Jeon, Jonathan Cechetto, Priscille Brodin

Future Med Chem· August 2010

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Antileishmanial high-throughput drug screening reveals drug candidates with new scaffolds.
Jair L Siqueira-Neto, Ok-Ryul Song, Hyunrim Oh, Jeong-Hun Sohn, Gyongseon Yang, Jonathan Cechetto

PLoS Negl Trop Dis· May 2010

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Confocal-based method for quantification of diffusion kinetics in microwell plates and its application for identifying a rapid mixing method for high-content/throughput screening.
Ok Ryul Song, Tae-Hee Kim, Xavier Perrodon, Changbok Lee, Hee Kyoung Jeon, Jonathan Cechetto

J Biomol Screen· February 2010

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Small-molecule screening made simple for a difficult target with a signaling nucleic acid aptamer that reports on deaminase activity.
Nadine H Elowe, Razvan Nutiu, Abdellah Allali-Hassani, Jonathan D Cechetto, Donald W Hughes

Angew Chem Int Ed Engl· August 2006

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Experimental screening of dihydrofolate reductase yields a "test set" of 50,000 small molecules for a computational data-mining and docking competition.
Nadine H Elowe, Jan E Blanchard, Jonathan D Cechetto, Eric D Brown

J Biomol Screen· October 2005

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Multicopy suppressors for novel antibacterial compounds reveal targets and drug efflux susceptibility.
Xiaoming Li, Michela Zolli-Juran, Jonathan D Cechetto, Denis M Daigle, Gerard D Wright

Chem Biol· October 2004

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High-throughput screening identifies inhibitors of the SARS coronavirus main proteinase.
Jan E Blanchard, Nadine H Elowe, Carly Huitema, Pascal D Fortin, Jonathan D Cechetto

Chem Biol· October 2004

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High throughput screening identifies novel inhibitors of Escherichia coli dihydrofolate reductase that are competitive with dihydrofolate.
Michela Zolli-Juran, Jonathan D Cechetto, Rebecca Hartlen, Denis M Daigle, Eric D Brown

Bioorg Med Chem Lett· August 2003

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