Publications by authors named "Yuin Han Loh"

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DMTF1 up-regulation rescues proliferation defect of telomere dysfunctional neural stem cells via the SWI/SNF-E2F axis.
Yajing Liang, Oleg V Grinchuk, Nadia Omega Cipta, Yingying Zeng, You Heng Chuah, Yuin-Han Loh

Sci Adv· January 2026

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Understanding the molecular basis of mesenchymal stem cell stemness: implications for clinical applications.
Tong Ming Liu, Wikie Tew, Zheng Yang, Bing Lim, James Hoi Po Hui, Yuin-Han Loh

Cell Death Dis· November 2025

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Septal LYVE1 macrophages control adipocyte stem cell adipogenic potential.
Xiaotong Yu, Yanan Hu, Hwee Ying Lim, Ziyi Li, Diego Adhemar Jaitin, Yuin-Han Loh

Science· August 2025

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Human embryo research: how to move towards a 28-day limit.
Alejandro De Los Angeles, Nissim Benvenisty, Hongkui Deng, Jacob H Hanna, Julian Koplin, Yuin-Han Loh

Nature· July 2025

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Extracellular Vesicles Administered via Intrathecal Injection Mediate Safe Delivery of Nucleic Acids to the Central Nervous System for Gene Therapy.
Brenda Wan Shing Lam, Melissa Tan, Chang Gao, Thach Tuan Pham, Lan Thi Ngoc Tran, Yuin-Han Loh

J Extracell Vesicles· July 2025

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Combination of KRAS ASO and RIG-I agonist in extracellular vesicles transforms the tumor microenvironment towards effective treatment of KRAS-dependent cancers.
Cao Dai Phung, Trinh T T Tran, Brendon Zhi Jie Yeo, Rebecca Carissa Prajogo, Evelyn Saudjana, Yuin-Han Loh

Theranostics· June 2025

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Supercharging CAR-T cells through transcriptional and epigenetic armoring.
Diyuan Qin, Yanna Lei, Pei Shu, Yugu Zhang, Yuin-Han Loh

Theranostics· May 2025

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Competing dynamic gene regulatory networks involved in fibroblast reprogramming to hematopoietic progenitor cells.
Samiyah Shafiq, Kiyofumi Hamashima, Laura A Guest, Ali H Al-Anbaki, Fabio M R Amaral, Yuin-Han Loh

Stem Cell Reports· May 2025

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Rewiring of SINE-MIR enhancer topology and Esrrb modulation in expanded and naive pluripotency.
Nadia Omega Cipta, Yingying Zeng, Ka Wai Wong, Zi Hao Zheng, Yao Yi, Yuin-Han Loh

Genome Biol· April 2025

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Morphokinetic Analyses of Fishing Cat-Domestic Cat Interspecies Somatic Cell Nuclear Transfer Embryos Through A Time-Lapse System.
Hai-Jun Liu, Serena Jocelyn Wai Yin Oh, Nicole Liling Tay, Christina Yingyan Lim, Chia-Da Hsu, Yuin-Han Loh

Animals (Basel)· January 2025

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Enterovirus-A71 preferentially infects and replicates in human motor neurons, inducing neurodegeneration by ferroptosis.
Wai Hon Chooi, Winanto, Yingying Zeng, Cheryl Yi-Pin Lee, Ze Qin Lim, Yuin-Han Loh

Emerg Microbes Infect· December 2024

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Nuclear receptor-SINE B1 network modulates expanded pluripotency in blastoids and blastocysts.
Ka Wai Wong, Yingying Zeng, Edison Tay, Jia Hao Jackie Teo, Nadia Omega Cipta, Yuin-Han Loh

Nat Commun· November 2024

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Deciphering tumour microenvironment and elucidating the origin of cancer cells in ovarian clear cell carcinoma.
Uma S Kamaraj, Pradeep Gautam, Terence Cheng, Tham Su Chin, Sun Kuie Tay, Yuin-Han Loh

bioRxiv· August 2024

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PHF2 regulates genome topology and DNA replication in neural stem cells via cohesin.
Jia Feng, You Heng Chuah, Yajing Liang, Nadia Omega Cipta, Yingying Zeng, Yuin-Han Loh

Nucleic Acids Res· July 2024

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Breaking NGF-TrkA immunosuppression in melanoma sensitizes immunotherapy for durable memory T cell protection.
Tao Yin, Guoping Wang, Liuyang Wang, Poorva Mudgal, Ergang Wang, Yuin-Han Loh

Nat Immunol· February 2024

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Deterministic reprogramming of neutrophils within tumors.
Melissa S F Ng, Immanuel Kwok, Leonard Tan, Changming Shi, Daniela Cerezo-Wallis, Yuin-Han Loh

Science· January 2024

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Integration-free induced pluripotent stem cells from three endangered Southeast Asian non-human primate species.
Qiuye Bao, Nicole Liling Tay, Christina Yingyan Lim, Delia Hwee Hoon Chua, Su Keyau Kee, Yuin-Han Loh

Sci Rep· January 2024

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DARESOME enables concurrent profiling of multiple DNA modifications with restriction enzymes in single cells and cell-free DNA.
Ramya Viswanathan, Elsie Cheruba, Pui-Mun Wong, Yao Yi, Shaun Ngang, Yuin-Han Loh

Sci Adv· September 2023

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Dose imbalance of DYRK1A kinase causes systemic progeroid status in Down syndrome by increasing the un-repaired DNA damage and reducing LaminB1 levels.
Aoife Murray, Gillian Gough, Ana Cindrić, Frano Vučković, David Koschut, Yuin-Han Loh

EBioMedicine· August 2023

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Endocytosis of red blood cell extracellular vesicles by macrophages leads to cytoplasmic heme release and prevents foam cell formation in atherosclerosis.
Thach Tuan Pham, Anh Hong Le, Cong Phi Dang, Suet Yen Chong, Dang Vinh Do, Yuin-Han Loh

J Extracell Vesicles· August 2023

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Single-nucleus multiomic mapping of mA methylomes and transcriptomes in native populations of cells with sn-m6A-CT.
Kiyofumi Hamashima, Ka Wai Wong, Tsz Wing Sam, Jia Hao Jackie Teo, Reshma Taneja, Yuin-Han Loh

Mol Cell· August 2023

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Editorial: Decoding immunologic complex systems in cancer: the cutting-edge technologies revolutionizing cancer immunology and immunotherapy.
Hu Li, Jin Zhang, Yuin Han Loh, Daniel D Billadeau

Front Immunol· May 2023

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ISSCR Education Committee syllabus and learning guide for enhancing stem cell literacy.
Julie R Perlin, William J Anderson, Sina Bartfeld, Anna Couturier, Yvanka de Soysa, Yuin-Han Loh

Stem Cell Reports· February 2023

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Ribosomal proteins regulate 2-cell-stage transcriptome in mouse embryonic stem cells.
Yao Yi, Yingying Zeng, Tsz Wing Sam, Kiyofumi Hamashima, Rachel Jun Rou Tan, Yuin-Han Loh

Stem Cell Reports· February 2023

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Robust generation of human-chambered cardiac organoids from pluripotent stem cells for improved modelling of cardiovascular diseases.
Beatrice Xuan Ho, Jeremy Kah Sheng Pang, Ying Chen, Yuin-Han Loh, Omer An

Stem Cell Res Ther· December 2022

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