Trends Cell Biol January 2016 PMID 26437586

Repair Pathway Choices and Consequences at the Double-Strand Break.

Raphael Ceccaldi, Beatrice Rondinelli, Alan D D'Andrea

Mentions

4
Peak: 3 in Feb 2020
across 2 sources since Feb 2019

Extended reach

7,633
potential audience

Total likes

118

Video views

7,313

Mentions per month

Feb 2019 – Feb 2020

Where it's discussed

  • X / Twitter2 posts
  • YouTube2 videos

AI synopsis

What people are saying

Evaluations highlight that posts concentrate on explaining gene editing and DNA repair pathways, using language like 'short presentations' and 'introduction,' which indicates an interest in foundational knowledge rather than deep analysis or controversy. The tone is educational and neutral, contributing to an overall modest level of engagement and impact in advancing or challenging scientific ideas.

AgreementNeither agree nor disagree

The discussion reflects a neutral stance, mainly focusing on explaining the topic without strong opinions for or against it.

InterestModerate interest

There is moderate interest, as the social discussions are centered on understanding gene editing and DNA repair mechanisms.

EngagementModerate engagement

Participants show some engagement by delving into basic concepts like cellular repair pathways, but there is limited depth or personal insight.

ImpactNeutral impact

The discussions have a minimal impact, serving primarily as informational or introductory content without influencing broader debates.

Abstract in brief

  • Double-strand breaks (DSBs) are dangerous to cells because they can cause mutations, chromosomal chaos, or cell death if not repaired properly.
  • Cells mainly use two repair methods: homologous recombination (HR), which is accurate, and classical nonhomologous end joining (C-NHEJ), which can be error-prone.
  • Recent research shows alternative repair pathways like altEJ and SSA also exist, often leading to genome instability and contributing to cancer development, with complex factors influencing which pathway is chosen.]

Top posts

Most liked on X and Bluesky
Genomics Gurus
@GenomicsGurus · X

GENE EDITING EXPLAINED! The first in a series of short presentations on gene editing This introduction covers cellular DNA repair pathways and the possible genome editing outcomes when using sequence-specific nucleases. https://t.co/rCnxY8xgNX via @YouTube

Feb 18, 2020 · 2 likes · 1 share · 130 followers View post →
Adam West
@chromatingroup · X

RT @GenomicsGurus: GENE EDITING EXPLAINED! The first in a series of short presentations on gene editing This introduction covers cellular…

Feb 18, 2020 · 1 share · 187 followers View post →

All mentions

Adam West
@chromatingroup · X

RT @GenomicsGurus: GENE EDITING EXPLAINED! The first in a series of short presentations on gene editing This introduction covers cellular…

Feb 18, 2020 · 1 share · 187 followers View post →
Genomics Gurus
@GenomicsGurus · X

GENE EDITING EXPLAINED! The first in a series of short presentations on gene editing This introduction covers cellular DNA repair pathways and the possible genome editing outcomes when using sequence-specific nucleases. https://t.co/rCnxY8xgNX via @YouTube

Feb 18, 2020 · 2 likes · 1 share · 130 followers View post →