Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein https://t.co/MWrbwzoR8C @arthurCantab @kirillnadezhdi2 @MariaKarela3
Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein.
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May 2023 – Aug 2023Where it's discussed
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The overall discussion reflects a neutral stance, with participants sharing basic acknowledgments and tagging each other for attention, such as @arthurCantab and @kirillnadezhdi2, indicating mild interest. The tone and wording suggest they recognize the scientific relevance but do not delve into detailed implications or critique.
The discussion includes members who acknowledge the publication but do not express strong opinions of support or disagreement.
Participants demonstrate some curiosity, especially regarding potential therapeutic implications, but overall engagement remains modest.
The exchange is somewhat superficial with mentions of the study's subject matter without deep analysis or critical discussion.
The comments have limited influence on shaping opinions or encouraging widespread consideration of the findings.
Abstract in brief
- The study reveals that the natural plant compound genistein binds inside the TRPV6 channel, blocking calcium flow and altering its shape to prevent it from opening.
- Using techniques like cryo-electron microscopy, electrophysiology, and computer simulations, researchers show genistein causes the channel to close by making specific structural changes.
- This new understanding of how genistein inhibits TRPV6 provides valuable insights for designing more effective drugs to target cancer-related cell growth.]
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Most liked on X and BlueskyRT @AlexanderSobol6: Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein https://t.co/MWrbwzo…
Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein 2日連続で出してきた、すげぇなこのグループ https://t.co/xlCA2Orvib https://t.co/eJJAsBuVwO
RT @AlexanderSobol6: Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein https://t.co/MWrbwzo…
RT @AlexanderSobol6: Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein https://t.co/MWrbwzo…
RT @AlexanderSobol6: Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein https://t.co/MWrbwzo…
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Mechanism of TRPV6 Inhibition by Natural Phytoestrogen Genistein
This study reveals that genistein binds within the TRPV6 channel, blocking calcium flow by inducing specific structural changes that prevent channel opening. Techniques like cryo-electron microscopy and simulations…
RT @AlexanderSobol6: Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein https://t.co/MWrbwzo…
RT @AlexanderSobol6: Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein https://t.co/MWrbwzo…
RT @AlexanderSobol6: Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein https://t.co/MWrbwzo…
RT @AlexanderSobol6: Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein https://t.co/MWrbwzo…
RT @AlexanderSobol6: Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein https://t.co/MWrbwzo…
RT @AlexanderSobol6: Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein https://t.co/MWrbwzo…
Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein 2日連続で出してきた、すげぇなこのグループ https://t.co/xlCA2Orvib https://t.co/eJJAsBuVwO
RT @AlexanderSobol6: Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein https://t.co/MWrbwzo…
Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein https://t.co/MWrbwzoR8C @arthurCantab @kirillnadezhdi2 @MariaKarela3