468,611 results match your criteria: "Pharmacologic Actions"

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Psilocybin as a lead candidate molecule in preclinical therapeutic studies of psychiatric disorders: A systematic review.
James J Gattuso, Carey Wilson, Anthony J Hannan, Thibault Renoir

J Neurochem· September 2024

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Antibiotics damage the colonic mucus barrier in a microbiota-independent manner.
Jasmin Sawaed, Lilach Zelik, Yehonatan Levin, Rachel Feeney, Maria Naama

September 2024

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Effect of Ubrogepant on Patient-Reported Outcomes When Administered During the Migraine Prodrome: Results From the Randomized PRODROME Trial.
Richard B Lipton, Andrea M Harriott, Julia Y Ma, Jonathan H Smith, Jonathan Stokes

Neurology· September 2024

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High-throughput virtual screening of phenylpyrimidine derivatives as selective JAK3 antagonists using computational methods.
Abdelmoujoud Faris, Ibrahim M Ibrahim, Hanine Hadni, Menana Elhallaoui

J Biomol Struct Dyn· September 2024

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The Influence of Dietary Isothiocyanates on the Effectiveness of Mitomycin C and Bacillus Calmette-Guérin in Treating Nonmuscle-Invasive Bladder Cancer.
Marilyn L Kwan, Zinian Wang, Reina Haque, Valerie S Lee, Janise M Roh

September 2024

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The role of complement in kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.
Marina Vivarelli, Jonathan Barratt, Laurence H Beck, Fadi Fakhouri, Daniel P Gale

Kidney Int· September 2024

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Why does circadian timing of administration matter for immune checkpoint inhibitors' efficacy?
Abdoulaye Karaboué, Pasquale F Innominato, Nicholas I Wreglesworth, Boris Duchemann, René Adam

September 2024

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Revisiting resistant hypertension in kidney disease.
Shweta Bansal

Curr Opin Nephrol Hypertens· September 2024

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Moringa oleifera leaf extracts improve exercise performance in young male adults: A pilot study.
Weiyun Dong, Xiangyu Bian, Min Wan, Lu Jin, Yanxian Wang

August 2024

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Electroacupuncture and carbamazepine for patients with trigeminal neuralgia: a randomized, controlled, 2 × 2 factorial trial.
Rongrong Li, Jing Sun, Kaitao Luo, Ning Luo, Ruohan Sun

J Neurol· August 2024

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Sacubitril/Valsartan Versus Enalapril in Chronic Chagas Cardiomyopathy: Rationale and Design of the PARACHUTE-HF Trial.
Edimar Alcides Bocchi, Luis E Echeverria, Caroline Demacq, Pedro Gabriel Melo de Barros E Silva, Lilian Mazza Barbosa

August 2024

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Mechanisms of action and therapeutic applications of GLP-1 and dual GIP/GLP-1 receptor agonists.
Qiyuan Keith Liu

Front Endocrinol (Lausanne)· August 2024

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Medications for Obesity: A Review.
Kimberly A Gudzune, Robert F Kushner

August 2024

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Optimal methods of vitamin D supplementation to prevent acute respiratory infections: a systematic review, dose-response and pairwise meta-analysis of randomized controlled trials.
Chih-Hung Wang, Lorenzo Porta, Ting-Kai Yang, Yu-Hsiang Wang, Tsung-Hung Wu

Nutr J· August 2024

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Psilocybin desynchronizes the human brain.
Joshua S Siegel, Subha Subramanian, Demetrius Perry, Benjamin P Kay, Evan M Gordon

August 2024

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Is microdosing a placebo? A rapid review of low-dose LSD and psilocybin research.
Vince Polito, Paul Liknaitzky

J Psychopharmacol· August 2024

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Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis: The BLING III Randomized Clinical Trial.
Joel M Dulhunty, Stephen J Brett, Jan J De Waele, Dorrilyn Rajbhandari, Laurent Billot

JAMA· August 2024

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Engineered matrices reveal stiffness-mediated chemoresistance in patient-derived pancreatic cancer organoids.
Bauer L LeSavage, Daiyao Zhang, Carla Huerta-López, Aidan E Gilchrist, Brad A Krajina

Nat Mater· August 2024

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KCNE4-dependent modulation of Kv1.3 pharmacology.
Daniel Sastre, Magalí Colomer-Molera, Angela de Benito-Bueno, Carmen Valenzuela, Gregorio Fernández-Ballester

Biochem Pharmacol· August 2024

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Risk of Nonarteritic Anterior Ischemic Optic Neuropathy in Patients Prescribed Semaglutide.
Jimena Tatiana Hathaway, Madhura P Shah, David B Hathaway, Seyedeh Maryam Zekavat, Drenushe Krasniqi

JAMA Ophthalmol· August 2024

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Medication-Induced Weight Change Across Common Antidepressant Treatments : A Target Trial Emulation Study.
Joshua Petimar, Jessica G Young, Han Yu, Sheryl L Rifas-Shiman, Matthew F Daley

Ann Intern Med· August 2024

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Cleaning products: Their chemistry, effects on indoor air quality, and implications for human health.
Heidi Salonen, Tunga Salthammer, Emmanuelle Castagnoli, Martin Täubel, Lidia Morawska

Environ Int· August 2024

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Combined Transcriptome and Circulating Tumor DNA Longitudinal Biomarker Analysis Associates With Clinical Outcomes in Advanced Solid Tumors Treated With Pembrolizumab.
Alberto Hernando-Calvo, S Y Cindy Yang, Maria Vila-Casadesús, Ming Han, Zhihui Amy Liu

JCO Precis Oncol· August 2024

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An Anti-Inflammatory Diet and Its Potential Benefit for Individuals with Mental Disorders and Neurodegenerative Diseases-A Narrative Review.
Sophie M van Zonneveld, Ellen J van den Oever, Benno C M Haarman, Emmy L Grandjean, Jasper O Nuninga

Nutrients· August 2024

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Pentoxifylline ameliorates subclinical atherosclerosis progression in patients with type 2 diabetes and chronic kidney disease: a randomized pilot trial.
Javier Donate-Correa, Carla M Ferri, Carmen Mora-Fernández, Nayra Pérez-Delgado, Ainhoa González-Luis

Cardiovasc Diabetol· August 2024

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Hypertension and Kidney Function After Living Kidney Donation.
Amit X Garg, Jennifer B Arnold, Meaghan S Cuerden, Christine Dipchand, Liane S Feldman

JAMA· July 2024

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Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes.
Vlado Perkovic, Katherine R Tuttle, Peter Rossing, Kenneth W Mahaffey, Johannes F E Mann

N Engl J Med· July 2024

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A Minireview on Nanosized Hypericin-Based Inducer of Immune Cell Death Under ROS-Based Therapies.
Chuanshan Xu, Xiaowen Cai, Lingran Du

Int J Nanomedicine· December 2025

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Unlocking Toll-Like Receptors: Targeting Therapeutics for Respiratory Tract Infections and Inflammatory Disorders.
Vishal Pandey, Debasis Sen, Sunny Rathee, Sakshi Soni, Shashank Mishra

Recent Adv Inflamm Allergy Drug Discov· December 2025

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Alantolactone as a Bioactive Sesquiterpene Lactone: Molecular Mechanisms and Anticancer Potential for Pharmaceutical Development.
Alice Njolke Mafe, Lipana Dorcas Bappa, Javad Sharifi-Rad, William N Setzer, Daniela Calina

Arch Pharm (Weinheim)· December 2025

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The Pharmacokinetics, Pharmacological Mechanisms and Clinical Application of Zhenwu Decoction.
Yongan Liao, Beini Lao, Huilian Jiang, Jiayi Ma, Yiwen Cao

Basic Clin Pharmacol Toxicol· January 2026

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First evidence of photoinactivation of rapidly growing mycobacteria by tetra-cationic porphyrins with peripheral cisplatin.
Thaíse D Fussinger, Paulo R de Souza, Bernardo A Iglesias, Marli M A de Campos

Braz J Microbiol· December 2025

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In silico docking yields small molecule negative allosteric modulators targeting the core of Frizzled 7.
Magdalena M Scharf, Julia Kinsolving, Lukas Grätz, Jan Hendrik Voss, David Carrasco-Busturia

Nat Commun· December 2025

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Galectin-1 induces macrophage immunometabolic reprogramming, modulates T cell immunity and attenuates atherosclerotic plaque formation.
Ya Li, Julian Leberzammer, Xavier Blanchet, Rundan Duan, Michael Lacy

Atherosclerosis· December 2025

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GCaMP6f-expressing chromaffin cells in murine adrenal slices exhibit dynamic spontaneous calcium responses that do not require nerve input.
Nicole M Procacci, Gale L Craviso, Normand Leblanc, Josette Zaklit, Jihwan Yoon

Cell Calcium· December 2025

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[Zinc-Dependent Histone Deacetylase (HDAC) Inhibitors: Therapeutic Potential, Pharmacophore Structure, and Methods for Testing Deacylase Activity].
A S Zemskaya, S N Kochetkov, M V Kozlov

Mol Biol (Mosk)· December 2025

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A Tutorial on the Development of a Physiologically Inspired PKRO Model for Monoclonal Antibodies.
Georgi I Kapitanov, David Flowers, Diana H Marcantonio, Timothy R Lezon, Josh F Apgar

CPT Pharmacometrics Syst Pharmacol· December 2025

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Unraveling anti-inflammatory metabolic signatures of Glycyrrhiza uralensis and isoliquiritigenin through multiomics.
Saki Kiuchi, Mi Hwa Chung, Hina Sakai, Taiki Nakaya, Katsuya Ohbuchi

NPJ Syst Biol Appl· December 2025

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Role of Dietary Polyphenols in NAD+-Dependent Deacetylase SIRT 1 in Stress-Induced Depression.
Nicole Less, Fúlvio Rieli Mendes, Giulio Maria Pasinetti

Mol Neurobiol· December 2025

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Constituents of essential oils as modulators of TRP channels: Focus on cognitive functions, neurodegenerative, and psychological diseases.
Olesia F Moroz, Viktoriia I Kravchenko, Alexander V Zholos

J Pharmacol Sci· January 2026

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Gellan gum-based nanocarriers for the delivery of anticancer agents: A review.
Saumyadeep Bora, Bhanu Priya, Deep Pooja, Hitesh Kulhari

Int J Biol Macromol· December 2025

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Integrative assessment of endocrine disruption: From in vitro mechanisms to species extrapolation - Highlights of the German Pharma-Tox Summit 2025.
Ute Haßmann, Lisa Gölz, René Geci, Konstantinos Stefanidis, Justin Lucky Brandt

Toxicology· December 2025

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Tricyclic antidepressant amitriptyline potentiates brain-derived neurotrophic factor expression mediated by PKC delta-NF-kappa B signaling in primary cultured astrocytes with connexin43-knockdown.
Nozomi Tokunaga, Rikako Fujimoto, Yoki Nakamura, Kazue Hisaoka-Nakashima, Norimitsu Morioka

Neurochem Int· December 2025

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Network pharmacology-based cocktail of four Ginkgo biloba compounds enhances yeast mitochondrial function and longevity.
Yi Ding, Jingjing Li, Junlin Li, Dengke Chen, Feifan Yu

Biochem Biophys Res Commun· December 2025

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Dehydrocostus lactone promotes ferroptosis by regulating the HMOX1/CDK1 axis during liver cancer treatment.
Kui Long, Zhitian Shi, Weiran Liao, Yutao He, Lixin Liu

Bioorg Chem· December 2025

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Synergistic combinations of antimicrobial peptides and conventional antibiotics: A strategy to delay resistance emergence in World Health Organization priority bacteria.
Cesar Augusto Roque-Borda, Qi Zhang, Thi Phuong Truc Nguyen, Thi Thu Hoai Nguyen, Himadri Medhi

Pharmacol Rev· November 2025

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Metformin-mechanisms of its glycemia-reducing effect.
Jürgen Drewe, Marc Foretz, Stephan Krähenbühl

Pharmacol Rev· November 2025

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Multifaceted anticancer mechanisms of tribenzyltin carboxylates: DNA minor groove targeting and inhibition of key enzymes in DNA replication, nucleotide synthesis, and redox homeostasis.
Theebaa Anasamy, Yiing Yee Foo, Wen Shang Saw, Yee Chu Kwa, Chuancheng Wei

Naunyn Schmiedebergs Arch Pharmacol· December 2025

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Visnagin attenuates thioacetamide-induced kidney damage through suppression of renal injury marker, oxidative stress, inflammation, apoptosis, and TGF-β-mediated renal fibrosis.
Akshay Amruta Navghare, Sonu Rajput, Poonam Yadav, Sumeet Kumar Singh, Yogender Goswami

Naunyn Schmiedebergs Arch Pharmacol· December 2025

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Coumarin benzamide scaffold as potential 5-HT inhibitors: a multiparametric investigation and molecular simulation.
Akenaton Onassis Cardoso Viana Gomes, Francisco Nithael Melo Lúcio, Matheus Nunes da Rocha, Victor Moreira de Oliveira, Caio Henrique Alexandre Roberto

J Mol Model· December 2025

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Uro-Protective Role of Lacosamide Against Cyclophosphamide-Induced Cystitis via Notch1/NICD/NF-κB Pathway: Network Pharmacology, Molecular Docking, and Rat Model Validation.
Ahmed S Abdel-Samea, Mohammed R A Ali, Reham H Mohyeldin, Mina Ezzat Attya, Basim A S Messiha

Arch Pharm (Weinheim)· December 2025

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In vitro anti-diabetic activity and molecular docking studies of Amaranthus cruentus, Amaranthus hybridus and isolated compounds.
Nolitha Nkobole, Oluwakemi Ebenezer, Gerhard Prinsloo

BMC Complement Med Ther· December 2025

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Alternate actions of CDK4/6 inhibitors beyond cell cycle blockade: unexplored roles in therapy resistance.
Domenica Scordamaglia, Marianna Talia, Azzurra Zicarelli, Adelina Assunta Mondino, Salvatore De Rosis

Cancer Metastasis Rev· December 2025

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Characterisation of an unusual nicotinic acetylcholine receptor subtype preferentially sensitive to biogenic amines.
Eleanor L Mitchell, Emily B Armstrong, Franco Viscarra, Isabel Bermudez, Philip C Biggin

Commun Biol· December 2025

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