Publications by authors named "Achim Brinker"

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A biochemical screen for GroEL/GroES inhibitors.
Steven M Johnson, Orzala Sharif, Puiying Annie Mak, Hsiao-Ting Wang, Ingo H Engels, Achim Brinker

Bioorg Med Chem Lett· February 2014

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Small molecule inhibitors of trans-translation have broad-spectrum antibiotic activity.
Nitya S Ramadoss, John N Alumasa, Lin Cheng, Yu Wang, Sharon Li, Achim Brinker

Proc Natl Acad Sci U S A· June 2013

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Pan-Src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells.
Judith Staerk, Costas A Lyssiotis, Lea A Medeiro, Michael Bollong, Ruth K Foreman, Achim Brinker

Angew Chem Int Ed Engl· June 2011

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Identification and characterization of small-molecule inducers of fetal hemoglobin.
Tae-gyu Nam, Jongkook Lee, John R Walker, Achim Brinker, Charles Y Cho

ChemMedChem· May 2011

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Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds.
Gregory J Crowther, Alberto J Napuli, James H Gilligan, Kerstin Gagaring, Rachel Borboa, Achim Brinker

Mol Biochem Parasitol· January 2011

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HTS-Compatible Patient-Derived Cell-Based Assay to Identify Small Molecule Modulators of Aberrant Splicing in Myotonic Dystrophy Type 1.
Debra A O'Leary, Leonardo Vargas, Orzala Sharif, Michael E Garcia, Yury J Sigal, Achim Brinker

Curr Chem Genomics· March 2010

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Identification of small molecule and genetic modulators of AON-induced dystrophin exon skipping by high-throughput screening.
Debra A O'Leary, Orzala Sharif, Paul Anderson, Buu Tu, Genevieve Welch, Achim Brinker

PLoS One· December 2009

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Time-resolved fluorescence resonance energy transfer and surface plasmon resonance-based assays for retinoid and transthyretin binding to retinol-binding protein 4.
Orzala Sharif, Huiyong Hu, Heath Klock, Eric N Hampton, Edward Nigoghossian, Achim Brinker

Anal Biochem· September 2009

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A time-resolved fluorescence resonance energy transfer-based assay for DEN1 peptidase activity.
Ingo H Engels, Catherine Daguia, Truc Huynh, Hugo Urbina, Jörg Buddenkotte, Achim Brinker

Anal Biochem· July 2009

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Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4.
Costas A Lyssiotis, Ruth K Foreman, Judith Staerk, Michael Garcia, Divya Mathur, Achim Brinker

Proc Natl Acad Sci U S A· June 2009

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An intracellular conformational sensor assay for Abl T315I.
Vicki Zhou, Xiaoqi Gao, Shulin Han, Achim Brinker, Jeremy S Caldwell

Anal Biochem· February 2009

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Measuring the tyrosine kinase activity: a review of biochemical and cellular assay technologies.
Yong Jia, Xiang-Ju Gu, Achim Brinker, Markus Warmuth

Expert Opin Drug Discov· August 2008

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In vivo incorporation of unnatural amino acids to probe structure, dynamics, and ligand binding in a large protein by nuclear magnetic resonance spectroscopy.
Susan E Cellitti, David H Jones, Leanna Lagpacan, Xueshi Hao, Qiong Zhang, Achim Brinker

J Am Chem Soc· July 2008

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In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
David Plouffe, Achim Brinker, Case McNamara, Kerstin Henson, Nobutaka Kato

Proc Natl Acad Sci U S A· July 2008

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Cellular Ser/Thr-kinase assays using generic peptide substrates.
Deanna G Adams, Yu Wang, Puiying A Mak, Jason Chyba, Orzala Shalizi, Achim Brinker

Curr Chem Genomics· May 2008

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Antibody microarrays using resonance light-scattering particles for detection.
Bernhard H Geierstanger, Petri Saviranta, Achim Brinker

Methods Mol Biol· July 2006

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Immunoassay and antibody microarray analysis of the HUPO Plasma Proteome Project reference specimens: systematic variation between sample types and calibration of mass spectrometry data.
Brian B Haab, Bernhard H Geierstanger, George Michailidis, Frank Vitzthum, Sara Forrester, Achim Brinker

Proteomics· August 2005

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Homogeneous high-throughput screening assays for HIV-1 integrase 3beta-processing and strand transfer activities.
Yu Wang, Heath Klock, Hong Yin, Karen Wolff, Kimberly Bieza, Achim Brinker

J Biomol Screen· August 2005

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Crystal structures of human HSP90alpha-complexed with dihydroxyphenylpyrazoles.
Andreas Kreusch, Shulin Han, Achim Brinker, Vicki Zhou, Ha-soon Choi

Bioorg Med Chem Lett· March 2005

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Evaluating sandwich immunoassays in microarray format in terms of the ambient analyte regime.
Petri Saviranta, Ryan Okon, Achim Brinker, Masaki Warashina, Joerg Eppinger

Clin Chem· October 2004

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A time-resolved fluorescence resonance energy transfer-based HTS assay and a surface plasmon resonance-based binding assay for heat shock protein 90 inhibitors.
Vicki Zhou, Shulin Han, Achim Brinker, Heath Klock, Jeremy Caldwell

Anal Biochem· August 2004

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Synthetic small molecules that control stem cell fate.
Sheng Ding, Tom Y H Wu, Achim Brinker, Eric C Peters, Wooyoung Hur

Proc Natl Acad Sci U S A· June 2003

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Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry.
Arthur R Salomon, Scott B Ficarro, Laurence M Brill, Achim Brinker, Qui T Phung

Proc Natl Acad Sci U S A· January 2003

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Structural plasticity and noncovalent substrate binding in the GroEL apical domain. A study using electrospay ionization mass spectrometry and fluorescence binding studies.
Alison E Ashcroft, Achim Brinker, Joseph E Coyle, Frank Weber, Markus Kaiser

J Biol Chem· September 2002

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The protein import motor of mitochondria: a targeted molecular ratchet driving unfolding and translocation.
Koji Okamoto, Achim Brinker, Stefan A Paschen, Ismail Moarefi, Manajit Hayer-Hartl

EMBO J· July 2002

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