Publications by authors named "Adam Linley"

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Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127.
Skye Montoya, Jessie Bourcier, Mark Noviski, Hao Lu, Meghan C Thompson, Adam Linley

Science· February 2024

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BTK-independent regulation of calcium signalling downstream of the B-cell receptor in malignant B-cells.
Rachael Arthur, Alexander Wathen, Elizabeth A Lemm, Freda K Stevenson, Francesco Forconi, Adam J Linley

Cell Signal· August 2022

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Mechanisms of Resistance to Noncovalent Bruton's Tyrosine Kinase Inhibitors.
Eric Wang, Xiaoli Mi, Meghan C Thompson, Skye Montoya, Ryan Q Notti, Adam J Linley

N Engl J Med· February 2022

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Kinobead Profiling Reveals Reprogramming of BCR Signaling in Response to Therapy within Primary CLL Cells.
Adam J Linley, Laura I Karydis, Anil K Mondru, Annalisa D'Avola, Humood Al Shmrany

Clin Cancer Res· October 2021

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Poor prognosis is ZAP70'ed into focus in CLL.
Adam J Linley, Joseph R Slupsky

Blood· July 2021

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New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome.
Leah J Wilson, Adam Linley, Dean E Hammond, Fiona E Hood, Judy M Coulson

Cancer Res· January 2018

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IL-4 enhances expression and function of surface IgM in CLL cells.
Maria M Aguilar-Hernandez, Matthew D Blunt, Rachel Dobson, Alison Yeomans, Stephen Thirdborough, Adam Linley

Blood· June 2016

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Engagement of the B-cell receptor of chronic lymphocytic leukemia cells drives global and MYC-specific mRNA translation.
Alison Yeomans, Stephen M Thirdborough, Beatriz Valle-Argos, Adam Linley, Sergey Krysov

Blood· January 2016

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Lectin binding to surface Ig variable regions provides a universal persistent activating signal for follicular lymphoma cells.
Adam Linley, Sergey Krysov, Maurilio Ponzoni, Peter W Johnson, Graham Packham

Blood· October 2015

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Higher levels of reactive oxygen species are associated with anergy in chronic lymphocytic leukemia.
Adam Linley, Beatriz Valle-Argos, Andrew J Steele, Freda K Stevenson, Francesco Forconi

Haematologica· July 2015

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Stimulation of surface IgM of chronic lymphocytic leukemia cells induces an unfolded protein response dependent on BTK and SYK.
Sergey Krysov, Andrew J Steele, Vania Coelho, Adam Linley, Marina Sanchez Hidalgo

Blood· November 2014

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The helicase HAGE expressed by malignant melanoma-initiating cells is required for tumor cell proliferation in vivo.
Adam J Linley, Morgan G Mathieu, Amanda K Miles, Robert C Rees, Stephanie E B McArdle

J Biol Chem· April 2012

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Tumour-associated antigens: considerations for their use in tumour immunotherapy.
Adam J Linley, Murrium Ahmad, Robert C Rees

Int J Hematol· March 2011

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HAGE, a cancer/testis antigen expressed at the protein level in a variety of cancers.
Morgan G Mathieu, Adam J Linley, Stephen P Reeder, Cécile Badoual, Eric Tartour

Cancer Immun· January 2010

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