Publications by authors named "Alex Burgin"

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Patterns of genomic deletions in monkeypox virus during the 2022 outbreak in the United States.
Crystal M Gigante, Daisy McGrath, Sophia Sukkestad, Hui Zhao, Mengfei Peng, Alex Burgin

Nat Commun· October 2025

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Coagulation factor XII haploinsufficiency is protective against venous thromboembolism in a population-scale multidimensional analysis.
Amelia K Haj, David S Paul, Sean J Jurgens, Harish Eswaran, Lu-Chen Weng, Alex Burgin

Nat Commun· September 2025

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Short-Read and Long-Read Whole Genome Sequencing for SARS-CoV-2 Variants Identification.
Mengfei Peng, Morgan L Davis, Meghan L Bentz, Alex Burgin, Mark Burroughs

Viruses· April 2025

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Sentinel Surveillance reveals phylogenetic diversity and detection of linear plasmids harboring and among enterococci collected in the United States.
Alyssa G Kent, Lori M Spicer, Davina Campbell, Erin Breaker, Gillian A McAllister, Alex Burgin

Antimicrob Agents Chemother· November 2024

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Genomics 2 Proteins portal: a resource and discovery tool for linking genetic screening outputs to protein sequences and structures.
Seulki Kwon, Jordan Safer, Duyen T Nguyen, David Hoksza, Patrick May, Alex Burgin

Nat Methods· October 2024

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Carbapenem-resistant Acinetobacter baumannii complex in the United States-An epidemiological and molecular description of isolates collected through the Emerging Infections Program, 2019.
Sandra N Bulens, Davina Campbell, Susannah L McKay, Nicholas Vlachos, Alex Burgin

Am J Infect Control· September 2024

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The benefits of translating biomedical research at drug discovery institutes.
David J Huggins, Jonathan Baell, Paul E Brennan, Alex Burgin, Duncan E Scott

Nat Rev Drug Discov· September 2024

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Genomics 2 Proteins portal: A resource and discovery tool for linking genetic screening outputs to protein sequences and structures.
Seulki Kwon, Jordan Safer, Duyen T Nguyen, David Hoksza, Patrick May, Alex Burgin

bioRxiv· January 2024

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SARS-CoV-2 viral shedding in vaccinated and unvaccinated persons: A case series.
David W McCormick, Liesl M Hagan, Phillip P Salvatore, Reed Magleby, Christine Lee, Alex Burgin

Vaccine· March 2023

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Effectiveness of two and three mRNA COVID-19 vaccine doses against Omicron- and Delta-Related outpatient illness among adults, October 2021-February 2022.
Sara S Kim, Jessie R Chung, H Keipp Talbot, Carlos G Grijalva, Karen J Wernli, Alex Burgin

Influenza Other Respir Viruses· November 2022

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Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex.
Jason J Kwon, Behnoush Hajian, Yuemin Bian, Lucy C Young, Alvaro J Amor, Alex Burgin

Nature· September 2022

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Genomic Surveillance for SARS-CoV-2 Variants: Predominance of the Delta (B.1.617.2) and Omicron (B.1.1.529) Variants - United States, June 2021-January 2022.
Anastasia S Lambrou, Philip Shirk, Molly K Steele, Prabasaj Paul, Clinton R Paden, Alex Burgin

MMWR Morb Mortal Wkly Rep· February 2022

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Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer.
James O'Connell, John Porter, Boris Kroeplien, Tim Norman, Stephen Rapecki, Alex Burgin

Nat Commun· December 2019

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Phenotypic Characterization of a Comprehensive Set of MAPK1/ERK2 Missense Mutants.
Lisa Brenan, Aleksandr Andreev, Ofir Cohen, Sasha Pantel, Atanas Kamburov, Alex B Burgin

Cell Rep· October 2016

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Some of the most interesting CASP11 targets through the eyes of their authors.
Andriy Kryshtafovych, John Moult, Arnaud Baslé, Alex Burgin, Timothy K Craig

Proteins· September 2016

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Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts.
Giambattista Guaitoli, Francesco Raimondi, Bernd K Gilsbach, Yacob Gómez-Llorente, Egon Deyaert, Alex Burgin

Proc Natl Acad Sci U S A· July 2016

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A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1.
Matthew C Clifton, David M Dranow, Alison Leed, Ben Fulroth, James W Fairman, Alex B Burgin

PLoS One· April 2016

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Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics.
Luc de Waal, Timothy A Lewis, Matthew G Rees, Aviad Tsherniak, Xiaoyun Wu, Alex B Burgin

Nat Chem Biol· February 2016

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Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor.
Thale C Jarvis, Douglas R Davies, Akihiko Hisaminato, Daniel I Resnicow, Shashi Gupta, Alex B Burgin

Structure· July 2015

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Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins.
Savannah E Sanchez, Daniel A Cuevas, Jason E Rostron, Tiffany Y Liang, Cullen G Pivaroff, Alex B Burgin

J Vis Exp· June 2015

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Phosphodiesterase-4 (PDE4) molecular pharmacology and Alzheimer's disease.
Mark E Gurney, Emily C D'Amato, Alex B Burgin

Neurotherapeutics· January 2015

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Discovery of triazines as selective PDE4B versus PDE4D inhibitors.
Timothy J Hagen, Xuesheng Mo, Alex B Burgin, David Fox, Zheng Zhang

Bioorg Med Chem Lett· August 2014

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Structural basis for the design of selective phosphodiesterase 4B inhibitors.
David Fox, Alex B Burgin, Mark E Gurney

Cell Signal· March 2014

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Challenging the state of the art in protein structure prediction: Highlights of experimental target structures for the 10th Critical Assessment of Techniques for Protein Structure Prediction Experiment CASP10.
Andriy Kryshtafovych, John Moult, Patrick Bales, J Fernando Bazan, Marco Biasini, Alex Burgin

Proteins· February 2014

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Structure and function of a cyanophage-encoded peptide deformylase.
Jeremy A Frank, Don Lorimer, Merry Youle, Pam Witte, Tim Craig, Alex B Burgin

ISME J· June 2013

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